4KK9A

Structure of the e148a mutant of clc-ec1 deltanc construct in 100mm fluoride and 2mm bromide
Total Genus 181
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
181
sequence length
443
structure length
443
Chain Sequence
RRRQLIRQLLERDKTPLAILFMAAVVGTLVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAPEAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGRAGPTVQIGGNIGRMVLDIFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAVFIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGMQDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLVFIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIAGMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILARTLAKQEAE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter.
pubmed doi rcsb
molecule keywords H(+)/Cl(-) exchange transporter ClcA
molecule tags Transport protein
source organism Escherichia coli
total genus 181
structure length 443
sequence length 443
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-05-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00654 Voltage_CLC Voltage gated chloride channel
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3080.10 Mainly Alpha Orthogonal Bundle Clc chloride channel Clc chloride channel 4kk9A00
1KPKA 3ND0A 3Q17A 2FEEA 3EJZA 2H2SA 2EXWA 2HT4A 4KKLA 2R9HA 4KK5A 4KKCA 2FEDA 4KJQA 4FG6A 2HTKA 4KK9A 2HT2A 4KKAA 2HT3A 3NMOA 4KJWA 4ENEA 2HTLA 3EJYA 2FECA 3ORGA 4LOUA 4FTPA 4KK6A 1KPLA 2HLFA 2H2PA 3DETA 1OTSA 1OTUA 4KK8A 2EXYA 4MQXA 5HD8A 1OTTA 4KKBA 4KJPA 2EZ0A
chains in the Genus database with same CATH superfamily
1KPKA 3ND0A 3Q17A 2FEEA 3EJZA 2H2SA 2EXWA 2HT4A 4KKLA 2R9HA 4KK5A 4KKCA 2FEDA 4KJQA 4FG6A 2HTKA 4KK9A 2HT2A 4KKAA 2HT3A 3NMOA 4KJWA 4ENEA 2HTLA 3EJYA 2FECA 3ORGA 4LOUA 4FTPA 4KK6A 1KPLA 2HLFA 2H2PA 3DETA 1OTSA 1OTUA 4KK8A 2EXYA 4MQXA 5HD8A 1OTTA 4KKBA 4KJPA 2EZ0A
chains in the Genus database with same CATH topology
1KPKA 3ND0A 3Q17A 2FEEA 3EJZA 2H2SA 2EXWA 2HT4A 4KKLA 2R9HA 4KK5A 4KKCA 2FEDA 4KJQA 4FG6A 2HTKA 4KK9A 2HT2A 4KKAA 2HT3A 3NMOA 4KJWA 4ENEA 2HTLA 3EJYA 2FECA 3ORGA 4LOUA 4FTPA 4KK6A 1KPLA 2HLFA 2H2PA 3DETA 1OTSA 1OTUA 4KK8A 2EXYA 4MQXA 5HD8A 1OTTA 4KKBA 4KJPA 2EZ0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KPK A;  3ND0 A;  3Q17 A;  2FEE A;  3EJZ A;  2H2S A;  2EXW A;  2HT4 A;  4KKL A;  2R9H A;  4KK5 A;  4KKC A;  2FED A;  4KJQ A;  4FG6 A;  2HTK A;  4KK9 A;  2HT2 A;  4KKA A;  2HT3 A;  3NMO A;  4KJW A;  4ENE A;  2HTL A;  3EJY A;  2FEC A;  3ORG A;  4LOU A;  4FTP A;  4KK6 A;  1KPL A;  2HLF A;  2H2P A;  3DET A;  1OTS A;  1OTU A;  4KK8 A;  2EXY A;  4MQX A;  5HD8 A;  1OTT A;  4KKB A;  4KJP A;  2EZ0 A; 
#chains in the Genus database with same CATH topology
 1KPK A;  3ND0 A;  3Q17 A;  2FEE A;  3EJZ A;  2H2S A;  2EXW A;  2HT4 A;  4KKL A;  2R9H A;  4KK5 A;  4KKC A;  2FED A;  4KJQ A;  4FG6 A;  2HTK A;  4KK9 A;  2HT2 A;  4KKA A;  2HT3 A;  3NMO A;  4KJW A;  4ENE A;  2HTL A;  3EJY A;  2FEC A;  3ORG A;  4LOU A;  4FTP A;  4KK6 A;  1KPL A;  2HLF A;  2H2P A;  3DET A;  1OTS A;  1OTU A;  4KK8 A;  2EXY A;  4MQX A;  5HD8 A;  1OTT A;  4KKB A;  4KJP A;  2EZ0 A; 
#chains in the Genus database with same CATH homology
 1KPK A;  3ND0 A;  3Q17 A;  2FEE A;  3EJZ A;  2H2S A;  2EXW A;  2HT4 A;  4KKL A;  2R9H A;  4KK5 A;  4KKC A;  2FED A;  4KJQ A;  4FG6 A;  2HTK A;  4KK9 A;  2HT2 A;  4KKA A;  2HT3 A;  3NMO A;  4KJW A;  4ENE A;  2HTL A;  3EJY A;  2FEC A;  3ORG A;  4LOU A;  4FTP A;  4KK6 A;  1KPL A;  2HLF A;  2H2P A;  3DET A;  1OTS A;  1OTU A;  4KK8 A;  2EXY A;  4MQX A;  5HD8 A;  1OTT A;  4KKB A;  4KJP A;  2EZ0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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