4KK9A

Structure of the e148a mutant of clc-ec1 deltanc construct in 100mm fluoride and 2mm bromide
Total Genus 181
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
181
sequence length
443
structure length
443
Chain Sequence
RRRQLIRQLLERDKTPLAILFMAAVVGTLVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAPEAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGRAGPTVQIGGNIGRMVLDIFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAVFIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGMQDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLVFIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIAGMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILARTLAKQEAE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter.
pubmed doi rcsb
molecule tags Transport protein
source organism Escherichia coli
molecule keywords H(+)/Cl(-) exchange transporter ClcA
total genus 181
structure length 443
sequence length 443
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-05-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00654 Voltage_CLC Voltage gated chloride channel
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3080.10 Mainly Alpha Orthogonal Bundle Clc chloride channel Clc chloride channel 4kk9A00
4KKAA 2H2SA 4KK6A 1KPKA 3DETA 3ND0A 2EZ0A 4KJWA 3Q17A 5HD8A 3ORGA 3EJYA 2HTLA 2HT2A 3NMOA 4FG6A 4KKCA 2H2PA 2HTKA 2R9HA 2FEEA 4KJPA 4KK5A 1KPLA 4MQXA 4LOUA 2EXYA 4ENEA 4KJQA 2FEDA 4KKBA 2HT3A 2EXWA 4KK9A 1OTTA 4KKLA 2FECA 3EJZA 2HT4A 1OTUA 1OTSA 4KK8A 2HLFA 4FTPA
chains in the Genus database with same CATH superfamily
4KKAA 2H2SA 4KK6A 1KPKA 3DETA 3ND0A 2EZ0A 4KJWA 3Q17A 5HD8A 3ORGA 3EJYA 2HTLA 2HT2A 3NMOA 4FG6A 4KKCA 2H2PA 2HTKA 2R9HA 2FEEA 4KJPA 4KK5A 1KPLA 4MQXA 4LOUA 2EXYA 4ENEA 4KJQA 2FEDA 4KKBA 2HT3A 2EXWA 4KK9A 1OTTA 4KKLA 2FECA 3EJZA 2HT4A 1OTUA 1OTSA 4KK8A 2HLFA 4FTPA
chains in the Genus database with same CATH topology
4KKAA 2H2SA 4KK6A 1KPKA 3DETA 3ND0A 2EZ0A 4KJWA 3Q17A 5HD8A 3ORGA 3EJYA 2HTLA 2HT2A 3NMOA 4FG6A 4KKCA 2H2PA 2HTKA 2R9HA 2FEEA 4KJPA 4KK5A 1KPLA 4MQXA 4LOUA 2EXYA 4ENEA 4KJQA 2FEDA 4KKBA 2HT3A 2EXWA 4KK9A 1OTTA 4KKLA 2FECA 3EJZA 2HT4A 1OTUA 1OTSA 4KK8A 2HLFA 4FTPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4KKA A;  2H2S A;  4KK6 A;  1KPK A;  3DET A;  3ND0 A;  2EZ0 A;  4KJW A;  3Q17 A;  5HD8 A;  3ORG A;  3EJY A;  2HTL A;  2HT2 A;  3NMO A;  4FG6 A;  4KKC A;  2H2P A;  2HTK A;  2R9H A;  2FEE A;  4KJP A;  4KK5 A;  1KPL A;  4MQX A;  4LOU A;  2EXY A;  4ENE A;  4KJQ A;  2FED A;  4KKB A;  2HT3 A;  2EXW A;  4KK9 A;  1OTT A;  4KKL A;  2FEC A;  3EJZ A;  2HT4 A;  1OTU A;  1OTS A;  4KK8 A;  2HLF A;  4FTP A; 
#chains in the Genus database with same CATH topology
 4KKA A;  2H2S A;  4KK6 A;  1KPK A;  3DET A;  3ND0 A;  2EZ0 A;  4KJW A;  3Q17 A;  5HD8 A;  3ORG A;  3EJY A;  2HTL A;  2HT2 A;  3NMO A;  4FG6 A;  4KKC A;  2H2P A;  2HTK A;  2R9H A;  2FEE A;  4KJP A;  4KK5 A;  1KPL A;  4MQX A;  4LOU A;  2EXY A;  4ENE A;  4KJQ A;  2FED A;  4KKB A;  2HT3 A;  2EXW A;  4KK9 A;  1OTT A;  4KKL A;  2FEC A;  3EJZ A;  2HT4 A;  1OTU A;  1OTS A;  4KK8 A;  2HLF A;  4FTP A; 
#chains in the Genus database with same CATH homology
 4KKA A;  2H2S A;  4KK6 A;  1KPK A;  3DET A;  3ND0 A;  2EZ0 A;  4KJW A;  3Q17 A;  5HD8 A;  3ORG A;  3EJY A;  2HTL A;  2HT2 A;  3NMO A;  4FG6 A;  4KKC A;  2H2P A;  2HTK A;  2R9H A;  2FEE A;  4KJP A;  4KK5 A;  1KPL A;  4MQX A;  4LOU A;  2EXY A;  4ENE A;  4KJQ A;  2FED A;  4KKB A;  2HT3 A;  2EXW A;  4KK9 A;  1OTT A;  4KKL A;  2FEC A;  3EJZ A;  2HT4 A;  1OTU A;  1OTS A;  4KK8 A;  2HLF A;  4FTP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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