4KK9A

Structure of the e148a mutant of clc-ec1 deltanc construct in 100mm fluoride and 2mm bromide
Total Genus 181
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
181
sequence length
443
structure length
443
Chain Sequence
RRRQLIRQLLERDKTPLAILFMAAVVGTLVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAPEAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGRAGPTVQIGGNIGRMVLDIFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAVFIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGMQDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLVFIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIAGMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILARTLAKQEAE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter.
pubmed doi rcsb
molecule keywords H(+)/Cl(-) exchange transporter ClcA
molecule tags Transport protein
source organism Escherichia coli
total genus 181
structure length 443
sequence length 443
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-05-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00654 Voltage_CLC Voltage gated chloride channel
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3080.10 Mainly Alpha Orthogonal Bundle Clc chloride channel Clc chloride channel 4kk9A00
1OTUA 2FEEA 4KK5A 2EZ0A 1OTTA 2HTLA 4KK8A 3DETA 2EXWA 4LOUA 4KK6A 4KKAA 2HTKA 3EJYA 2FECA 2HT2A 3ORGA 3EJZA 4KKBA 2FEDA 4ENEA 2H2SA 4MQXA 5HD8A 4KKLA 2HT3A 4FTPA 4KJWA 2HLFA 2H2PA 4KK9A 2HT4A 4KJQA 3Q17A 4KKCA 1OTSA 4KJPA 3ND0A 3NMOA 1KPLA 2R9HA 4FG6A 1KPKA 2EXYA
chains in the Genus database with same CATH superfamily
1OTUA 2FEEA 4KK5A 2EZ0A 1OTTA 2HTLA 4KK8A 3DETA 2EXWA 4LOUA 4KK6A 4KKAA 2HTKA 3EJYA 2FECA 2HT2A 3ORGA 3EJZA 4KKBA 2FEDA 4ENEA 2H2SA 4MQXA 5HD8A 4KKLA 2HT3A 4FTPA 4KJWA 2HLFA 2H2PA 4KK9A 2HT4A 4KJQA 3Q17A 4KKCA 1OTSA 4KJPA 3ND0A 3NMOA 1KPLA 2R9HA 4FG6A 1KPKA 2EXYA
chains in the Genus database with same CATH topology
1OTUA 2FEEA 4KK5A 2EZ0A 1OTTA 2HTLA 4KK8A 3DETA 2EXWA 4LOUA 4KK6A 4KKAA 2HTKA 3EJYA 2FECA 2HT2A 3ORGA 3EJZA 4KKBA 2FEDA 4ENEA 2H2SA 4MQXA 5HD8A 4KKLA 2HT3A 4FTPA 4KJWA 2HLFA 2H2PA 4KK9A 2HT4A 4KJQA 3Q17A 4KKCA 1OTSA 4KJPA 3ND0A 3NMOA 1KPLA 2R9HA 4FG6A 1KPKA 2EXYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1OTU A;  2FEE A;  4KK5 A;  2EZ0 A;  1OTT A;  2HTL A;  4KK8 A;  3DET A;  2EXW A;  4LOU A;  4KK6 A;  4KKA A;  2HTK A;  3EJY A;  2FEC A;  2HT2 A;  3ORG A;  3EJZ A;  4KKB A;  2FED A;  4ENE A;  2H2S A;  4MQX A;  5HD8 A;  4KKL A;  2HT3 A;  4FTP A;  4KJW A;  2HLF A;  2H2P A;  4KK9 A;  2HT4 A;  4KJQ A;  3Q17 A;  4KKC A;  1OTS A;  4KJP A;  3ND0 A;  3NMO A;  1KPL A;  2R9H A;  4FG6 A;  1KPK A;  2EXY A; 
#chains in the Genus database with same CATH topology
 1OTU A;  2FEE A;  4KK5 A;  2EZ0 A;  1OTT A;  2HTL A;  4KK8 A;  3DET A;  2EXW A;  4LOU A;  4KK6 A;  4KKA A;  2HTK A;  3EJY A;  2FEC A;  2HT2 A;  3ORG A;  3EJZ A;  4KKB A;  2FED A;  4ENE A;  2H2S A;  4MQX A;  5HD8 A;  4KKL A;  2HT3 A;  4FTP A;  4KJW A;  2HLF A;  2H2P A;  4KK9 A;  2HT4 A;  4KJQ A;  3Q17 A;  4KKC A;  1OTS A;  4KJP A;  3ND0 A;  3NMO A;  1KPL A;  2R9H A;  4FG6 A;  1KPK A;  2EXY A; 
#chains in the Genus database with same CATH homology
 1OTU A;  2FEE A;  4KK5 A;  2EZ0 A;  1OTT A;  2HTL A;  4KK8 A;  3DET A;  2EXW A;  4LOU A;  4KK6 A;  4KKA A;  2HTK A;  3EJY A;  2FEC A;  2HT2 A;  3ORG A;  3EJZ A;  4KKB A;  2FED A;  4ENE A;  2H2S A;  4MQX A;  5HD8 A;  4KKL A;  2HT3 A;  4FTP A;  4KJW A;  2HLF A;  2H2P A;  4KK9 A;  2HT4 A;  4KJQ A;  3Q17 A;  4KKC A;  1OTS A;  4KJP A;  3ND0 A;  3NMO A;  1KPL A;  2R9H A;  4FG6 A;  1KPK A;  2EXY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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