4NODA

Distinct structural features of tfam drive mitochondrial dna packaging versus transcriptional activation
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
190
structure length
190
Chain Sequence
SVLASCPKKPVSSYLRFSKEQLPIFKAQNPDAKTTELIRRIAQRWRELPDSKKKIYQDAYRAEWQVYKEEISRFKEQLTPSQIMSLEKEIMDKHLKRKAMTKKKELTLLGKPKRPRSAYNVYVAERFQEAKGDSPQEKLKTVKENWKNLSDSEKELYIQHAKEDETRYHNEMKSWEEQMIEVGRKDLLRR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation.
pubmed doi rcsb
molecule tags Transcription regulator/dna
source organism Homo sapiens
molecule keywords Transcription factor A, mitochondrial
total genus 69
structure length 190
sequence length 190
chains with identical sequence B, G, H
ec nomenclature
pdb deposition date 2013-11-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00505 HMG_box HMG (high mobility group) box
A PF09011 HMG_box_2 HMG-box domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.30.10 Mainly Alpha Orthogonal Bundle DNA Binding (I), subunit A High mobility group box domain 4nodA02
1.10.30.10 Mainly Alpha Orthogonal Bundle DNA Binding (I), subunit A High mobility group box domain 4nodA01
2LEFA 1HSNA 1WZ6A 2CTOA 2CO9A 3U2BC 2HDZA 2CS1A 1K99A 1HRZA 3FGHA 2LE4A 4EUWA 3TMMA 1J5NA 1WGFA 1HRYA 2LY4A 1HMEA 4NODA 1LWMA 2YULA 1CG7A 1V63A 3F27D 1J3CA 2YUKA 3TQ6A 1L8YA 2E6OA 1GT0D 1QRVA 1NHNA 2YRQA 4S2QD 1J3DA 2CRJA 1J47A 1J46A 4Y60C 1CKTA 1HMAA 1L8ZA 2LHJA 4NNUA 1NHMA 4QR9A 2RTUA 1O4XB 3NM9A 4A3NA 2EQZA 2D7LA 1E7JA 1J3XA 1HMFA 1HSMA 1WXLA 2YQIA 1I11A 1AABA 1V64A 2GZKA
chains in the Genus database with same CATH superfamily
2LEFA 1HSNA 1WZ6A 2CTOA 3ABOB 2CO9A 3U2BC 2HDZA 2VSFA 2CS1A 1K99A 1HRZA 3FGHA 2LE4A 4EUWA 3ABSB 3TMMA 1WGFA 1J5NA 2LY4A 1HMEA 1HRYA 4NODA 1LWMA 2YULA 1CG7A 1V63A 3F27D 5H8WA 3ANYB 1J3CA 2YUKA 3TQ6A 1L8YA 2E6OA 1GT0D 1QRVA 1NHNA 2YRQA 4S2QD 1J3DA 2CRJA 4A15A 1J47A 3ABRB 1J46A 4Y60C 1CKTA 1HMAA 1L8ZA 2LHJA 4NNUA 1NHMA 4QR9A 2RTUA 1O4XB 3NM9A 4A3NA 2EQZA 2D7LA 1E7JA 1J3XA 1HMFA 4KQEA 1HSMA 1WXLA 3AO0B 2YQIA 1I11A 1AABA 1V64A 2GZKA
chains in the Genus database with same CATH topology
2LEFA 1HSNA 1WZ6A 2CTOA 2CO9A 3U2BC 2HDZA 2CS1A 1K99A 1HRZA 3FGHA 2LE4A 4EUWA 3TMMA 1J5NA 1WGFA 1HRYA 2LY4A 1HMEA 4NODA 1LWMA 2YULA 1CG7A 1V63A 3F27D 1J3CA 2YUKA 3TQ6A 1L8YA 2E6OA 1GT0D 1QRVA 1NHNA 2YRQA 4S2QD 1J3DA 2CRJA 1J47A 1J46A 4Y60C 1CKTA 1HMAA 1L8ZA 2LHJA 4NNUA 1NHMA 4QR9A 2RTUA 1O4XB 3NM9A 4A3NA 2EQZA 2D7LA 1E7JA 1J3XA 1HMFA 1HSMA 1WXLA 2YQIA 1I11A 1AABA 1V64A 2GZKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LEF A;  1HSN A;  1WZ6 A;  2CTO A;  2CO9 A;  3U2B C;  2HDZ A;  2CS1 A;  1K99 A;  1HRZ A;  3FGH A;  2LE4 A;  4EUW A;  3TMM A;  1J5N A;  1WGF A;  1HRY A;  2LY4 A;  1HME A;  4NOD A;  1LWM A;  2YUL A;  1CG7 A;  1V63 A;  3F27 D;  1J3C A;  2YUK A;  3TQ6 A;  1L8Y A;  2E6O A;  1GT0 D;  1QRV A;  1NHN A;  2YRQ A;  4S2Q D;  1J3D A;  2CRJ A;  1J47 A;  1J46 A;  4Y60 C;  1CKT A;  1HMA A;  1L8Z A;  2LHJ A;  4NNU A;  1NHM A;  4QR9 A;  2RTU A;  1O4X B;  3NM9 A;  4A3N A;  2EQZ A;  2D7L A;  1E7J A;  1J3X A;  1HMF A;  1HSM A;  1WXL A;  2YQI A;  1I11 A;  1AAB A;  1V64 A;  2GZK A; 
#chains in the Genus database with same CATH topology
 2LEF A;  1HSN A;  1WZ6 A;  2CTO A;  3ABO B;  2CO9 A;  3U2B C;  2HDZ A;  2VSF A;  2CS1 A;  1K99 A;  1HRZ A;  3FGH A;  2LE4 A;  4EUW A;  3ABS B;  3TMM A;  1WGF A;  1J5N A;  2LY4 A;  1HME A;  1HRY A;  4NOD A;  1LWM A;  2YUL A;  1CG7 A;  1V63 A;  3F27 D;  5H8W A;  3ANY B;  1J3C A;  2YUK A;  3TQ6 A;  1L8Y A;  2E6O A;  1GT0 D;  1QRV A;  1NHN A;  2YRQ A;  4S2Q D;  1J3D A;  2CRJ A;  4A15 A;  1J47 A;  3ABR B;  1J46 A;  4Y60 C;  1CKT A;  1HMA A;  1L8Z A;  2LHJ A;  4NNU A;  1NHM A;  4QR9 A;  2RTU A;  1O4X B;  3NM9 A;  4A3N A;  2EQZ A;  2D7L A;  1E7J A;  1J3X A;  1HMF A;  4KQE A;  1HSM A;  1WXL A;  3AO0 B;  2YQI A;  1I11 A;  1AAB A;  1V64 A;  2GZK A; 
#chains in the Genus database with same CATH homology
 2LEF A;  1HSN A;  1WZ6 A;  2CTO A;  2CO9 A;  3U2B C;  2HDZ A;  2CS1 A;  1K99 A;  1HRZ A;  3FGH A;  2LE4 A;  4EUW A;  3TMM A;  1J5N A;  1WGF A;  1HRY A;  2LY4 A;  1HME A;  4NOD A;  1LWM A;  2YUL A;  1CG7 A;  1V63 A;  3F27 D;  1J3C A;  2YUK A;  3TQ6 A;  1L8Y A;  2E6O A;  1GT0 D;  1QRV A;  1NHN A;  2YRQ A;  4S2Q D;  1J3D A;  2CRJ A;  1J47 A;  1J46 A;  4Y60 C;  1CKT A;  1HMA A;  1L8Z A;  2LHJ A;  4NNU A;  1NHM A;  4QR9 A;  2RTU A;  1O4X B;  3NM9 A;  4A3N A;  2EQZ A;  2D7L A;  1E7J A;  1J3X A;  1HMF A;  1HSM A;  1WXL A;  2YQI A;  1I11 A;  1AAB A;  1V64 A;  2GZK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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