4QR9A

Crystal structure of two hmgb1 box a domains cooperating to underwind and kink a dna
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
75
structure length
75
Chain Sequence
GSKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Two high-mobility group box domains act together to underwind and kink DNA.
pubmed doi rcsb
molecule tags Dna binding protein
source organism Rattus norvegicus
molecule keywords High mobility group protein B1
total genus 27
structure length 75
sequence length 75
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-06-30
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.30.10 Mainly Alpha Orthogonal Bundle DNA Binding (I), subunit A High mobility group box domain 4qr9A00
1HMAA 1L8ZA 2CS1A 2YUKA 2GZKA 1V64A 2LE4A 1AABA 2D7LA 1HRZA 1WZ6A 1O4XB 1WXLA 4S2QD 2LHJA 3TQ6A 1QRVA 2CO9A 2HDZA 2RTUA 1HMFA 1CG7A 1GT0D 4A3NA 2CTOA 1J46A 4NNUA 2LEFA 1J3XA 1J47A 2CRJA 1NHNA 2YQIA 1E7JA 3F27D 4EUWA 2YULA 1L8YA 1V63A 1WGFA 2EQZA 2E6OA 3TMMA 1J3CA 1J3DA 2YRQA 1I11A 1HSNA 1HSMA 4QR9A 3FGHA 1K99A 3U2BC 1HMEA 3NM9A 2LY4A 1HRYA 1CKTA 4Y60C 1LWMA 1NHMA 4NODA 1J5NA
chains in the Genus database with same CATH superfamily
1HMAA 3ANYB 1L8ZA 2CS1A 2YUKA 2GZKA 1V64A 2LE4A 3ABOB 2D7LA 1AABA 1HRZA 1WZ6A 1O4XB 1WXLA 4S2QD 2LHJA 3TQ6A 5H8WA 1QRVA 1J3DA 2CO9A 2HDZA 2RTUA 4KQEA 1HMFA 2VSFA 3ABRB 3AO0B 1CG7A 1GT0D 4A3NA 2CTOA 1J46A 4NNUA 4A15A 2LEFA 1J3XA 1J47A 2CRJA 1NHNA 2YQIA 1E7JA 3F27D 4EUWA 2YULA 1L8YA 1V63A 1WGFA 2EQZA 2E6OA 3ABSB 3TMMA 1J3CA 2YRQA 1I11A 1HSNA 1HSMA 4QR9A 3FGHA 1K99A 3U2BC 1HMEA 3NM9A 2LY4A 1HRYA 1CKTA 4Y60C 1LWMA 1NHMA 4NODA 1J5NA
chains in the Genus database with same CATH topology
1HMAA 1L8ZA 2CS1A 2YUKA 2GZKA 1V64A 2LE4A 1AABA 2D7LA 1HRZA 1WZ6A 1O4XB 1WXLA 4S2QD 2LHJA 3TQ6A 1QRVA 2CO9A 2HDZA 2RTUA 1HMFA 1CG7A 1GT0D 4A3NA 2CTOA 1J46A 4NNUA 2LEFA 1J3XA 1J47A 2CRJA 1NHNA 2YQIA 1E7JA 3F27D 4EUWA 2YULA 1L8YA 1V63A 1WGFA 2EQZA 2E6OA 3TMMA 1J3CA 1J3DA 2YRQA 1I11A 1HSNA 1HSMA 4QR9A 3FGHA 1K99A 3U2BC 1HMEA 3NM9A 2LY4A 1HRYA 1CKTA 4Y60C 1LWMA 1NHMA 4NODA 1J5NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HMA A;  1L8Z A;  2CS1 A;  2YUK A;  2GZK A;  1V64 A;  2LE4 A;  1AAB A;  2D7L A;  1HRZ A;  1WZ6 A;  1O4X B;  1WXL A;  4S2Q D;  2LHJ A;  3TQ6 A;  1QRV A;  2CO9 A;  2HDZ A;  2RTU A;  1HMF A;  1CG7 A;  1GT0 D;  4A3N A;  2CTO A;  1J46 A;  4NNU A;  2LEF A;  1J3X A;  1J47 A;  2CRJ A;  1NHN A;  2YQI A;  1E7J A;  3F27 D;  4EUW A;  2YUL A;  1L8Y A;  1V63 A;  1WGF A;  2EQZ A;  2E6O A;  3TMM A;  1J3C A;  1J3D A;  2YRQ A;  1I11 A;  1HSN A;  1HSM A;  4QR9 A;  3FGH A;  1K99 A;  3U2B C;  1HME A;  3NM9 A;  2LY4 A;  1HRY A;  1CKT A;  4Y60 C;  1LWM A;  1NHM A;  4NOD A;  1J5N A; 
#chains in the Genus database with same CATH topology
 1HMA A;  3ANY B;  1L8Z A;  2CS1 A;  2YUK A;  2GZK A;  1V64 A;  2LE4 A;  3ABO B;  2D7L A;  1AAB A;  1HRZ A;  1WZ6 A;  1O4X B;  1WXL A;  4S2Q D;  2LHJ A;  3TQ6 A;  5H8W A;  1QRV A;  1J3D A;  2CO9 A;  2HDZ A;  2RTU A;  4KQE A;  1HMF A;  2VSF A;  3ABR B;  3AO0 B;  1CG7 A;  1GT0 D;  4A3N A;  2CTO A;  1J46 A;  4NNU A;  4A15 A;  2LEF A;  1J3X A;  1J47 A;  2CRJ A;  1NHN A;  2YQI A;  1E7J A;  3F27 D;  4EUW A;  2YUL A;  1L8Y A;  1V63 A;  1WGF A;  2EQZ A;  2E6O A;  3ABS B;  3TMM A;  1J3C A;  2YRQ A;  1I11 A;  1HSN A;  1HSM A;  4QR9 A;  3FGH A;  1K99 A;  3U2B C;  1HME A;  3NM9 A;  2LY4 A;  1HRY A;  1CKT A;  4Y60 C;  1LWM A;  1NHM A;  4NOD A;  1J5N A; 
#chains in the Genus database with same CATH homology
 1HMA A;  1L8Z A;  2CS1 A;  2YUK A;  2GZK A;  1V64 A;  2LE4 A;  1AAB A;  2D7L A;  1HRZ A;  1WZ6 A;  1O4X B;  1WXL A;  4S2Q D;  2LHJ A;  3TQ6 A;  1QRV A;  2CO9 A;  2HDZ A;  2RTU A;  1HMF A;  1CG7 A;  1GT0 D;  4A3N A;  2CTO A;  1J46 A;  4NNU A;  2LEF A;  1J3X A;  1J47 A;  2CRJ A;  1NHN A;  2YQI A;  1E7J A;  3F27 D;  4EUW A;  2YUL A;  1L8Y A;  1V63 A;  1WGF A;  2EQZ A;  2E6O A;  3TMM A;  1J3C A;  1J3D A;  2YRQ A;  1I11 A;  1HSN A;  1HSM A;  4QR9 A;  3FGH A;  1K99 A;  3U2B C;  1HME A;  3NM9 A;  2LY4 A;  1HRY A;  1CKT A;  4Y60 C;  1LWM A;  1NHM A;  4NOD A;  1J5N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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