4R5QA

Crystal structure and nuclease activity of the crispr-associated cas4 protein pcal_0546 from pyrobaculum calidifontis containing a [2fe-2s] cluster
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
215
structure length
215
Chain Sequence
FNGMELLSPKPLCSVVNCEDLEKLDHVSALNELRREQEIFKLLPGIYAHRYDFRRVSPSIINDFEYCPRLLWVQHKLGLKLLSEKSVVSIIRGRILHERYERLLSQYENVVAEYKVEIGDLVGVVDLVIKRGGEYIPVEIKTGFSKEAHKTQLQIYISMLKARFGYLVYRNHVEVVHRNDAALDVLKKIREILSAREAPPAKCNSCIFKPICKNL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure and nuclease activity of the CRISPR-associated Cas4 protein Pcal_0546 from Pyrobaculum calidifontis containing a [2Fe-2S] cluster
rcsb
molecule tags Hydrolase
source organism Pyrobaculum calidifontis jcm 11548
molecule keywords CRISPR-associated exonuclease, Cas4 family
total genus 58
structure length 215
sequence length 215
ec nomenclature ec 3.1.12.1: 5' to 3' exodeoxyribonuclease (nucleoside 3'-phosphate-forming).
pdb deposition date 2014-08-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01930 Cas_Cas4 Domain of unknown function DUF83
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.320.10 Alpha Beta Alpha-Beta Complex Lambda Exonuclease; Chain A Lambda Exonuclease; Chain A 4r5qA00
5LD2B 1AVQA 3SYYA 3SM4A 3SZ5A 1W36B 3SZ4A 4WUZA 3K70B 3H4RA 3L0AA 4IC1A 4CEIA 3U44A 4R5QA 4CEJA 3K93A 3U4QA 3SLPA 4CEHA
chains in the Genus database with same CATH superfamily
5LD2B 1MROC 3POTC 1E6VC 3SQGC 1AVQA 1HBOC 3SYYA 3SM4A 3M32C 5A0YC 3SZ5A 1HBMC 1E6YC 1W36B 3SZ4A 4WUZA 3K70B 3H4RA 3L0AA 3M2UC 4IC1A 5A8WC 4CEIA 1HBUC 5G0RC 3U44A 4R5QA 4CEJA 3K93A 1HBNC 3M30C 5A8KC 3M2RC 3U4QA 3M1VC 3SLPA 4CEHA 3M2VC 5A8RC
chains in the Genus database with same CATH topology
5LD2B 1AVQA 3SYYA 3SM4A 3SZ5A 1W36B 3SZ4A 4WUZA 3K70B 3H4RA 3L0AA 4IC1A 4CEIA 3U44A 4R5QA 4CEJA 3K93A 3U4QA 3SLPA 4CEHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5LD2 B;  1AVQ A;  3SYY A;  3SM4 A;  3SZ5 A;  1W36 B;  3SZ4 A;  4WUZ A;  3K70 B;  3H4R A;  3L0A A;  4IC1 A;  4CEI A;  3U44 A;  4R5Q A;  4CEJ A;  3K93 A;  3U4Q A;  3SLP A;  4CEH A; 
#chains in the Genus database with same CATH topology
 5LD2 B;  1MRO C;  3POT C;  1E6V C;  3SQG C;  1AVQ A;  1HBO C;  3SYY A;  3SM4 A;  3M32 C;  5A0Y C;  3SZ5 A;  1HBM C;  1E6Y C;  1W36 B;  3SZ4 A;  4WUZ A;  3K70 B;  3H4R A;  3L0A A;  3M2U C;  4IC1 A;  5A8W C;  4CEI A;  1HBU C;  5G0R C;  3U44 A;  4R5Q A;  4CEJ A;  3K93 A;  1HBN C;  3M30 C;  5A8K C;  3M2R C;  3U4Q A;  3M1V C;  3SLP A;  4CEH A;  3M2V C;  5A8R C; 
#chains in the Genus database with same CATH homology
 5LD2 B;  1AVQ A;  3SYY A;  3SM4 A;  3SZ5 A;  1W36 B;  3SZ4 A;  4WUZ A;  3K70 B;  3H4R A;  3L0A A;  4IC1 A;  4CEI A;  3U44 A;  4R5Q A;  4CEJ A;  3K93 A;  3U4Q A;  3SLP A;  4CEH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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