4R5QA

Crystal structure and nuclease activity of the crispr-associated cas4 protein pcal_0546 from pyrobaculum calidifontis containing a [2fe-2s] cluster
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
215
structure length
215
Chain Sequence
FNGMELLSPKPLCSVVNCEDLEKLDHVSALNELRREQEIFKLLPGIYAHRYDFRRVSPSIINDFEYCPRLLWVQHKLGLKLLSEKSVVSIIRGRILHERYERLLSQYENVVAEYKVEIGDLVGVVDLVIKRGGEYIPVEIKTGFSKEAHKTQLQIYISMLKARFGYLVYRNHVEVVHRNDAALDVLKKIREILSAREAPPAKCNSCIFKPICKNL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure and nuclease activity of the CRISPR-associated Cas4 protein Pcal_0546 from Pyrobaculum calidifontis containing a [2Fe-2S] cluster
rcsb
molecule tags Hydrolase
source organism Pyrobaculum calidifontis jcm 11548
molecule keywords CRISPR-associated exonuclease, Cas4 family
total genus 58
structure length 215
sequence length 215
ec nomenclature ec 3.1.12.1: 5' to 3' exodeoxyribonuclease (nucleoside 3'-phosphate-forming).
pdb deposition date 2014-08-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01930 Cas_Cas4 Domain of unknown function DUF83
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.320.10 Alpha Beta Alpha-Beta Complex Lambda Exonuclease; Chain A Lambda Exonuclease; Chain A 4r5qA00
3SLPA 3K93A 4R5QA 3SYYA 3H4RA 3SZ4A 3U44A 3SZ5A 4CEJA 4CEIA 1W36B 4IC1A 3L0AA 5LD2B 4WUZA 3U4QA 3SM4A 3K70B 1AVQA 4CEHA
chains in the Genus database with same CATH superfamily
3M1VC 5A0YC 1E6YC 3SLPA 1E6VC 3K93A 5A8RC 4R5QA 3SYYA 3U4QA 4CEHA 1HBOC 3M30C 3SQGC 3M2UC 3H4RA 3SZ4A 3U44A 3POTC 3SZ5A 5A8WC 1HBNC 4CEJA 3M32C 4CEIA 1MROC 3M2VC 5A8KC 1W36B 4IC1A 3L0AA 5LD2B 1HBMC 4WUZA 1HBUC 3SM4A 3K70B 1AVQA 3M2RC 5G0RC
chains in the Genus database with same CATH topology
3SLPA 3K93A 4R5QA 3SYYA 3H4RA 3SZ4A 3U44A 3SZ5A 4CEJA 4CEIA 1W36B 4IC1A 3L0AA 5LD2B 4WUZA 3U4QA 3SM4A 3K70B 1AVQA 4CEHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3SLP A;  3K93 A;  4R5Q A;  3SYY A;  3H4R A;  3SZ4 A;  3U44 A;  3SZ5 A;  4CEJ A;  4CEI A;  1W36 B;  4IC1 A;  3L0A A;  5LD2 B;  4WUZ A;  3U4Q A;  3SM4 A;  3K70 B;  1AVQ A;  4CEH A; 
#chains in the Genus database with same CATH topology
 3M1V C;  5A0Y C;  1E6Y C;  3SLP A;  1E6V C;  3K93 A;  5A8R C;  4R5Q A;  3SYY A;  3U4Q A;  4CEH A;  1HBO C;  3M30 C;  3SQG C;  3M2U C;  3H4R A;  3SZ4 A;  3U44 A;  3POT C;  3SZ5 A;  5A8W C;  1HBN C;  4CEJ A;  3M32 C;  4CEI A;  1MRO C;  3M2V C;  5A8K C;  1W36 B;  4IC1 A;  3L0A A;  5LD2 B;  1HBM C;  4WUZ A;  1HBU C;  3SM4 A;  3K70 B;  1AVQ A;  3M2R C;  5G0R C; 
#chains in the Genus database with same CATH homology
 3SLP A;  3K93 A;  4R5Q A;  3SYY A;  3H4R A;  3SZ4 A;  3U44 A;  3SZ5 A;  4CEJ A;  4CEI A;  1W36 B;  4IC1 A;  3L0A A;  5LD2 B;  4WUZ A;  3U4Q A;  3SM4 A;  3K70 B;  1AVQ A;  4CEH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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