4S2QD

Crystal structure of hmg domain of the chondrogenesis master regulator, sox9 in complex with chip-seq identified dna element
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
76
structure length
76
Chain Sequence
PHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPRR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal Structure of HMG domain of the chondrogenesis master regulator, Sox9 in complex with ChIP-Seq identified DNA element
rcsb
molecule tags Dna binding protein/dna
source organism Mus musculus
molecule keywords DNA (5'-D(P*AP*GP*GP*CP*TP*TP*TP*GP*TP*TP*CP*TP*CP*CP*TP*G)-
total genus 22
structure length 76
sequence length 76
ec nomenclature
pdb deposition date 2015-01-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00505 HMG_box HMG (high mobility group) box
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.30.10 Mainly Alpha Orthogonal Bundle DNA Binding (I), subunit A High mobility group box domain 4s2qD00
1LWMA 1WGFA 3FGHA 1K99A 1J47A 2HDZA 4EUWA 1O4XB 1GT0D 1J3CA 1J3XA 3NM9A 2LEFA 2YRQA 2D7LA 1HRYA 2LHJA 4NODA 3TQ6A 1J3DA 2CTOA 1V63A 1HMAA 1L8YA 2YUKA 1HMEA 2CRJA 1CG7A 1J46A 2CS1A 1I11A 1V64A 2YULA 3TMMA 3F27D 4Y60C 1HMFA 4S2QD 3U2BC 1J5NA 1WXLA 1L8ZA 1HSNA 1WZ6A 1QRVA 2LY4A 1NHMA 2E6OA 2EQZA 4A3NA 1HRZA 1AABA 1CKTA 2LE4A 4NNUA 2GZKA 1E7JA 2CO9A 1HSMA 4QR9A 2RTUA 2YQIA 1NHNA
chains in the Genus database with same CATH superfamily
1LWMA 1WGFA 3FGHA 3ABRB 1K99A 1J47A 2HDZA 4EUWA 1O4XB 1GT0D 1J3CA 1J3XA 3NM9A 2LEFA 2YRQA 2D7LA 1HRYA 2LHJA 4NODA 3TQ6A 1J3DA 2CTOA 1V63A 1HMAA 3AO0B 3ANYB 1L8YA 2YUKA 1HMEA 4QR9A 2CRJA 1CG7A 1J46A 2CS1A 4KQEA 1I11A 1V64A 2YULA 3TMMA 3ABSB 3F27D 4Y60C 1HMFA 4S2QD 3U2BC 1J5NA 1WXLA 1L8ZA 1HSNA 3ABOB 1WZ6A 1QRVA 2LY4A 1NHMA 2E6OA 2EQZA 4A3NA 1HRZA 4A15A 1AABA 1CKTA 2LE4A 4NNUA 2GZKA 1E7JA 2CO9A 1HSMA 5H8WA 2YQIA 2RTUA 2VSFA 1NHNA
chains in the Genus database with same CATH topology
1LWMA 1WGFA 3FGHA 1K99A 1J47A 2HDZA 4EUWA 1O4XB 1GT0D 1J3CA 1J3XA 3NM9A 2LEFA 2YRQA 2D7LA 1HRYA 2LHJA 4NODA 3TQ6A 1J3DA 2CTOA 1V63A 1HMAA 1L8YA 2YUKA 1HMEA 2CRJA 1CG7A 1J46A 2CS1A 1I11A 1V64A 2YULA 3TMMA 3F27D 4Y60C 1HMFA 4S2QD 3U2BC 1J5NA 1WXLA 1L8ZA 1HSNA 1WZ6A 1QRVA 2LY4A 1NHMA 2E6OA 2EQZA 4A3NA 1HRZA 1AABA 1CKTA 2LE4A 4NNUA 2GZKA 1E7JA 2CO9A 1HSMA 4QR9A 2RTUA 2YQIA 1NHNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LWM A;  1WGF A;  3FGH A;  1K99 A;  1J47 A;  2HDZ A;  4EUW A;  1O4X B;  1GT0 D;  1J3C A;  1J3X A;  3NM9 A;  2LEF A;  2YRQ A;  2D7L A;  1HRY A;  2LHJ A;  4NOD A;  3TQ6 A;  1J3D A;  2CTO A;  1V63 A;  1HMA A;  1L8Y A;  2YUK A;  1HME A;  2CRJ A;  1CG7 A;  1J46 A;  2CS1 A;  1I11 A;  1V64 A;  2YUL A;  3TMM A;  3F27 D;  4Y60 C;  1HMF A;  4S2Q D;  3U2B C;  1J5N A;  1WXL A;  1L8Z A;  1HSN A;  1WZ6 A;  1QRV A;  2LY4 A;  1NHM A;  2E6O A;  2EQZ A;  4A3N A;  1HRZ A;  1AAB A;  1CKT A;  2LE4 A;  4NNU A;  2GZK A;  1E7J A;  2CO9 A;  1HSM A;  4QR9 A;  2RTU A;  2YQI A;  1NHN A; 
#chains in the Genus database with same CATH topology
 1LWM A;  1WGF A;  3FGH A;  3ABR B;  1K99 A;  1J47 A;  2HDZ A;  4EUW A;  1O4X B;  1GT0 D;  1J3C A;  1J3X A;  3NM9 A;  2LEF A;  2YRQ A;  2D7L A;  1HRY A;  2LHJ A;  4NOD A;  3TQ6 A;  1J3D A;  2CTO A;  1V63 A;  1HMA A;  3AO0 B;  3ANY B;  1L8Y A;  2YUK A;  1HME A;  4QR9 A;  2CRJ A;  1CG7 A;  1J46 A;  2CS1 A;  4KQE A;  1I11 A;  1V64 A;  2YUL A;  3TMM A;  3ABS B;  3F27 D;  4Y60 C;  1HMF A;  4S2Q D;  3U2B C;  1J5N A;  1WXL A;  1L8Z A;  1HSN A;  3ABO B;  1WZ6 A;  1QRV A;  2LY4 A;  1NHM A;  2E6O A;  2EQZ A;  4A3N A;  1HRZ A;  4A15 A;  1AAB A;  1CKT A;  2LE4 A;  4NNU A;  2GZK A;  1E7J A;  2CO9 A;  1HSM A;  5H8W A;  2YQI A;  2RTU A;  2VSF A;  1NHN A; 
#chains in the Genus database with same CATH homology
 1LWM A;  1WGF A;  3FGH A;  1K99 A;  1J47 A;  2HDZ A;  4EUW A;  1O4X B;  1GT0 D;  1J3C A;  1J3X A;  3NM9 A;  2LEF A;  2YRQ A;  2D7L A;  1HRY A;  2LHJ A;  4NOD A;  3TQ6 A;  1J3D A;  2CTO A;  1V63 A;  1HMA A;  1L8Y A;  2YUK A;  1HME A;  2CRJ A;  1CG7 A;  1J46 A;  2CS1 A;  1I11 A;  1V64 A;  2YUL A;  3TMM A;  3F27 D;  4Y60 C;  1HMF A;  4S2Q D;  3U2B C;  1J5N A;  1WXL A;  1L8Z A;  1HSN A;  1WZ6 A;  1QRV A;  2LY4 A;  1NHM A;  2E6O A;  2EQZ A;  4A3N A;  1HRZ A;  1AAB A;  1CKT A;  2LE4 A;  4NNU A;  2GZK A;  1E7J A;  2CO9 A;  1HSM A;  4QR9 A;  2RTU A;  2YQI A;  1NHN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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