4Y5OA

Ccm2 hhd in complex with mekk3 npb1
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
78
structure length
78
Chain Sequence
ASATELLQDYMLTLRTKLSSQEIQQFAALLHEYRNGASIHEFCINLRQLYGDSRKFLLLGLRPFIPEKDSQHFENFLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure and vascular function of MEKK3-cerebral cavernous malformations 2 complex.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Malcavernin
total genus 27
structure length 78
sequence length 78
ec nomenclature
pdb deposition date 2015-02-11
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1160.20 Mainly Alpha Up-down Bundle Paired amphipathic helix 2 (pah2 repeat) Paired amphipathic helix 2 (pah2 repeat) 4y5oA00
2LSRA 2KBRA 4YKCA 5F3XA 2KBQA 4Y5OA 4FQNA 3K1RA 4YKDA 4YL6A
chains in the Genus database with same CATH superfamily
1PD7A 4Y5OA 2L9SB 2RMSA 2LD7B 4YL6A 1S5QB 4YKDA 2LSRA 2KBRA 1S5RB 5F3XA 2KBQA 2F05A 3K1RA 2RMRA 1E91A 2CR7A 4YKCA 1G1EB 2CZYA 4FQNA
chains in the Genus database with same CATH topology
2LSRA 2KBRA 4YKCA 5F3XA 2KBQA 4Y5OA 4FQNA 3K1RA 4YKDA 4YL6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LSR A;  2KBR A;  4YKC A;  5F3X A;  2KBQ A;  4Y5O A;  4FQN A;  3K1R A;  4YKD A;  4YL6 A; 
#chains in the Genus database with same CATH topology
 1PD7 A;  4Y5O A;  2L9S B;  2RMS A;  2LD7 B;  4YL6 A;  1S5Q B;  4YKD A;  2LSR A;  2KBR A;  1S5R B;  5F3X A;  2KBQ A;  2F05 A;  3K1R A;  2RMR A;  1E91 A;  2CR7 A;  4YKC A;  1G1E B;  2CZY A;  4FQN A; 
#chains in the Genus database with same CATH homology
 2LSR A;  2KBR A;  4YKC A;  5F3X A;  2KBQ A;  4Y5O A;  4FQN A;  3K1R A;  4YKD A;  4YL6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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