4YKCA

Crystal structure of cerebral cavernous malformation 2 c-terminal adaptor domain
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
148
structure length
104
Chain Sequence
MELSASATELLQDYMLTLRTKLSSQEIQQFAALLHEYRNGASIHEFCINLRQLYGDSRKFLLLGLRPFIPEKDSQHFENFLETIGVKDWDRMISDISSDIEALG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Insights into the Molecular Recognition between Cerebral Cavernous Malformation 2 and Mitogen-Activated Protein Kinase Kinase Kinase 3
pubmed doi rcsb
molecule keywords Malcavernin
molecule tags Protein binding
source organism Homo sapiens
total genus 39
structure length 104
sequence length 148
ec nomenclature
pdb deposition date 2015-03-04
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1160.20 Mainly Alpha Up-down Bundle Paired amphipathic helix 2 (pah2 repeat) Paired amphipathic helix 2 (pah2 repeat) 4ykcA00
3K1RA 2KBRA 5F3XA 4FQNA 2KBQA 4Y5OA 4YKCA 4YKDA 4YL6A 2LSRA
chains in the Genus database with same CATH superfamily
1E91A 4Y5OA 4YKCA 2LSRA 2KBRA 1G1EB 1S5RB 2F05A 1PD7A 2RMRA 2L9SB 2CR7A 2RMSA 3K1RA 5F3XA 4FQNA 2CZYA 4YKDA 2KBQA 2LD7B 4YL6A 1S5QB
chains in the Genus database with same CATH topology
3K1RA 2KBRA 5F3XA 4FQNA 2KBQA 4Y5OA 4YKCA 4YKDA 4YL6A 2LSRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3K1R A;  2KBR A;  5F3X A;  4FQN A;  2KBQ A;  4Y5O A;  4YKC A;  4YKD A;  4YL6 A;  2LSR A; 
#chains in the Genus database with same CATH topology
 1E91 A;  4Y5O A;  4YKC A;  2LSR A;  2KBR A;  1G1E B;  1S5R B;  2F05 A;  1PD7 A;  2RMR A;  2L9S B;  2CR7 A;  2RMS A;  3K1R A;  5F3X A;  4FQN A;  2CZY A;  4YKD A;  2KBQ A;  2LD7 B;  4YL6 A;  1S5Q B; 
#chains in the Genus database with same CATH homology
 3K1R A;  2KBR A;  5F3X A;  4FQN A;  2KBQ A;  4Y5O A;  4YKC A;  4YKD A;  4YL6 A;  2LSR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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