4YKCA

Crystal structure of cerebral cavernous malformation 2 c-terminal adaptor domain
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
148
structure length
104
Chain Sequence
MELSASATELLQDYMLTLRTKLSSQEIQQFAALLHEYRNGASIHEFCINLRQLYGDSRKFLLLGLRPFIPEKDSQHFENFLETIGVKDWDRMISDISSDIEALG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Insights into the Molecular Recognition between Cerebral Cavernous Malformation 2 and Mitogen-Activated Protein Kinase Kinase Kinase 3
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Malcavernin
total genus 39
structure length 104
sequence length 148
ec nomenclature
pdb deposition date 2015-03-04
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1160.20 Mainly Alpha Up-down Bundle Paired amphipathic helix 2 (pah2 repeat) Paired amphipathic helix 2 (pah2 repeat) 4ykcA00
4YL6A 4Y5OA 3K1RA 4FQNA 5F3XA 2KBRA 2KBQA 4YKCA 2LSRA 4YKDA
chains in the Genus database with same CATH superfamily
2RMRA 1PD7A 2L9SB 1S5RB 2KBRA 4YKCA 2LSRA 2LD7B 2CR7A 2RMSA 1G1EB 2KBQA 4Y5OA 4FQNA 5F3XA 1E91A 2CZYA 1S5QB 4YKDA 2F05A 4YL6A 3K1RA
chains in the Genus database with same CATH topology
4YL6A 4Y5OA 3K1RA 4FQNA 5F3XA 2KBRA 2KBQA 4YKCA 2LSRA 4YKDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YL6 A;  4Y5O A;  3K1R A;  4FQN A;  5F3X A;  2KBR A;  2KBQ A;  4YKC A;  2LSR A;  4YKD A; 
#chains in the Genus database with same CATH topology
 2RMR A;  1PD7 A;  2L9S B;  1S5R B;  2KBR A;  4YKC A;  2LSR A;  2LD7 B;  2CR7 A;  2RMS A;  1G1E B;  2KBQ A;  4Y5O A;  4FQN A;  5F3X A;  1E91 A;  2CZY A;  1S5Q B;  4YKD A;  2F05 A;  4YL6 A;  3K1R A; 
#chains in the Genus database with same CATH homology
 4YL6 A;  4Y5O A;  3K1R A;  4FQN A;  5F3X A;  2KBR A;  2KBQ A;  4YKC A;  2LSR A;  4YKD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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