4YKDA

Crystal structure of truncated cerebral cavernous malformation 2 c-terminal adaptor domain
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
84
structure length
84
Chain Sequence
ASATELLQDYMLTLRTKLSSQEIQQFAALLHEYRNGASIHEFCINLRQLYGDSRKFLLLGLRPFIPEKDSQHFENFLETIGVKD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Insights into the Molecular Recognition between Cerebral Cavernous Malformation 2 and Mitogen-Activated Protein Kinase Kinase Kinase 3
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Malcavernin
total genus 33
structure length 84
sequence length 84
ec nomenclature
pdb deposition date 2015-03-04
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1160.20 Mainly Alpha Up-down Bundle Paired amphipathic helix 2 (pah2 repeat) Paired amphipathic helix 2 (pah2 repeat) 4ykdA00
4Y5OA 5F3XA 4YL6A 3K1RA 4YKCA 4YKDA 2KBQA 2LSRA 2KBRA 4FQNA
chains in the Genus database with same CATH superfamily
2RMRA 4Y5OA 2KBQA 2LSRA 2CZYA 4YKCA 2KBRA 2LD7B 5F3XA 1PD7A 4YKDA 2CR7A 2RMSA 4YL6A 1G1EB 1S5QB 3K1RA 2L9SB 1S5RB 1E91A 4FQNA 2F05A
chains in the Genus database with same CATH topology
4Y5OA 5F3XA 4YL6A 3K1RA 4YKCA 4YKDA 2KBQA 2LSRA 2KBRA 4FQNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4Y5O A;  5F3X A;  4YL6 A;  3K1R A;  4YKC A;  4YKD A;  2KBQ A;  2LSR A;  2KBR A;  4FQN A; 
#chains in the Genus database with same CATH topology
 2RMR A;  4Y5O A;  2KBQ A;  2LSR A;  2CZY A;  4YKC A;  2KBR A;  2LD7 B;  5F3X A;  1PD7 A;  4YKD A;  2CR7 A;  2RMS A;  4YL6 A;  1G1E B;  1S5Q B;  3K1R A;  2L9S B;  1S5R B;  1E91 A;  4FQN A;  2F05 A; 
#chains in the Genus database with same CATH homology
 4Y5O A;  5F3X A;  4YL6 A;  3K1R A;  4YKC A;  4YKD A;  2KBQ A;  2LSR A;  2KBR A;  4FQN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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