4YL6A

Crystal structure of truncated cerebral cavernous malformation 2 c-terminal adaptor domain in complex with an internal helix of mitogen-activated protein kinase kinase kinase 3
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
88
structure length
88
Chain Sequence
LSASATELLQDYMLTLRTKLSSQEIQQFAALLHEYRNGASIHEFCINLRQLYGDSRKFLLLGLRPFIPEKDSQHFENFLETIGVKDLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Insights into the Molecular Recognition between Cerebral Cavernous Malformation 2 and Mitogen-Activated Protein Kinase Kinase Kinase 3
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Malcavernin
total genus 33
structure length 88
sequence length 88
ec nomenclature
pdb deposition date 2015-03-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1160.20 Mainly Alpha Up-down Bundle Paired amphipathic helix 2 (pah2 repeat) Paired amphipathic helix 2 (pah2 repeat) 4yl6A00
4FQNA 2KBRA 4YKCA 3K1RA 4Y5OA 4YL6A 5F3XA 4YKDA 2KBQA 2LSRA
chains in the Genus database with same CATH superfamily
2CZYA 2L9SB 1G1EB 4Y5OA 4YKDA 1E91A 2LSRA 4FQNA 4YKCA 1S5QB 2CR7A 2F05A 3K1RA 4YL6A 2KBQA 2KBRA 2RMRA 2LD7B 1S5RB 2RMSA 1PD7A 5F3XA
chains in the Genus database with same CATH topology
4FQNA 2KBRA 4YKCA 3K1RA 4Y5OA 4YL6A 5F3XA 4YKDA 2KBQA 2LSRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FQN A;  2KBR A;  4YKC A;  3K1R A;  4Y5O A;  4YL6 A;  5F3X A;  4YKD A;  2KBQ A;  2LSR A; 
#chains in the Genus database with same CATH topology
 2CZY A;  2L9S B;  1G1E B;  4Y5O A;  4YKD A;  1E91 A;  2LSR A;  4FQN A;  4YKC A;  1S5Q B;  2CR7 A;  2F05 A;  3K1R A;  4YL6 A;  2KBQ A;  2KBR A;  2RMR A;  2LD7 B;  1S5R B;  2RMS A;  1PD7 A;  5F3X A; 
#chains in the Genus database with same CATH homology
 4FQN A;  2KBR A;  4YKC A;  3K1R A;  4Y5O A;  4YL6 A;  5F3X A;  4YKD A;  2KBQ A;  2LSR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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