4E2TA

Crystal structures of rada intein from pyrococcus horikoshii
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
172
structure length
172
Chain Sequence
AFARDTEVYYENDTVPHMESIEEMYSKYASMNGELPFDNGYAVPLDNVFVYTLDIASGEIKKTRASYIYREKVEKLIEIKLSSGYSLKVTPSHPVLLFRDGLQWVPAAEVKPGDVVVGVREEVLRRRIISKGELEFHEVSSVRIIDYNNWVYDLVIPETHNFIAPNGLVLHN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title NMR and Crystal Structures of the Pyrococcus horikoshii RadA Intein Guide a Strategy for Engineering a Highly Efficient and Promiscuous Intein.
pubmed doi rcsb
molecule tags Unknown function
source organism Pyrococcus horikoshii
molecule keywords Pho radA intein
total genus 42
structure length 172
sequence length 172
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-03-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF14890 Intein_splicing Intein splicing domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.16.10 Mainly Beta Beta Complex Endonuclease - Pi-scei; Chain A, domain 1 Hedgehog/Intein (Hint) domain 4e2tA00
2KEQA 1AT0A 5K08A 1JVAA 4GIGA 1EF0A 3NZMA 1GPPA 4O1RA 4OZ6A 2CW7A 1UM2A 2LCJA 2JMZA 1ZDEA 3IFJA 1DQ3A 4E2TA 1ZD7A 4KL6A 2LQMA 2IN8A 2IMZA 2L8LA 2LWYA 3IGDA 1LWSA 4E2UA 1MI8A 1DFAA 1VDEA 2CW8A 2JNQA 5I0AA 4KL5A 1LWTA 1AM2A 2IN9A 4O1SA 2IN0A
chains in the Genus database with same CATH superfamily
2KEQA 1AT0A 5K08A 1JVAA 4GIGA 1EF0A 3NZMA 1GPPA 4O1RA 4OZ6A 2CW7A 1UM2A 2LCJA 2JMZA 1ZDEA 3IFJA 1DQ3A 4E2TA 1ZD7A 4KL6A 2LQMA 2IN8A 4QFQA 2IMZA 2L8LA 2LWYA 3IGDA 1LWSA 4E2UA 1MI8A 1DFAA 1VDEA 4LX3A 2CW8A 2JNQA 5I0AA 4KL5A 1LWTA 1AM2A 2IN9A 4O1SA 2IN0A
chains in the Genus database with same CATH topology
2KEQA 1AT0A 5K08A 1JVAA 4GIGA 1EF0A 3NZMA 1GPPA 4O1RA 4OZ6A 2CW7A 1UM2A 2LCJA 2JMZA 1ZDEA 3IFJA 1DQ3A 4E2TA 1ZD7A 4KL6A 2LQMA 2IN8A 2IMZA 2L8LA 2LWYA 3IGDA 1LWSA 4E2UA 1MI8A 1DFAA 1VDEA 2CW8A 2JNQA 5I0AA 4KL5A 1LWTA 1AM2A 2IN9A 4O1SA 2IN0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KEQ A;  1AT0 A;  5K08 A;  1JVA A;  4GIG A;  1EF0 A;  3NZM A;  1GPP A;  4O1R A;  4OZ6 A;  2CW7 A;  1UM2 A;  2LCJ A;  2JMZ A;  1ZDE A;  3IFJ A;  1DQ3 A;  4E2T A;  1ZD7 A;  4KL6 A;  2LQM A;  2IN8 A;  2IMZ A;  2L8L A;  2LWY A;  3IGD A;  1LWS A;  4E2U A;  1MI8 A;  1DFA A;  1VDE A;  2CW8 A;  2JNQ A;  5I0A A;  4KL5 A;  1LWT A;  1AM2 A;  2IN9 A;  4O1S A;  2IN0 A; 
#chains in the Genus database with same CATH topology
 2KEQ A;  1AT0 A;  5K08 A;  1JVA A;  4GIG A;  1EF0 A;  3NZM A;  1GPP A;  4O1R A;  4OZ6 A;  2CW7 A;  1UM2 A;  2LCJ A;  2JMZ A;  1ZDE A;  3IFJ A;  1DQ3 A;  4E2T A;  1ZD7 A;  4KL6 A;  2LQM A;  2IN8 A;  4QFQ A;  2IMZ A;  2L8L A;  2LWY A;  3IGD A;  1LWS A;  4E2U A;  1MI8 A;  1DFA A;  1VDE A;  4LX3 A;  2CW8 A;  2JNQ A;  5I0A A;  4KL5 A;  1LWT A;  1AM2 A;  2IN9 A;  4O1S A;  2IN0 A; 
#chains in the Genus database with same CATH homology
 2KEQ A;  1AT0 A;  5K08 A;  1JVA A;  4GIG A;  1EF0 A;  3NZM A;  1GPP A;  4O1R A;  4OZ6 A;  2CW7 A;  1UM2 A;  2LCJ A;  2JMZ A;  1ZDE A;  3IFJ A;  1DQ3 A;  4E2T A;  1ZD7 A;  4KL6 A;  2LQM A;  2IN8 A;  2IMZ A;  2L8L A;  2LWY A;  3IGD A;  1LWS A;  4E2U A;  1MI8 A;  1DFA A;  1VDE A;  2CW8 A;  2JNQ A;  5I0A A;  4KL5 A;  1LWT A;  1AM2 A;  2IN9 A;  4O1S A;  2IN0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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