4L1OA

Crystal structure of human aldh3a1 with inhibitor 1-{[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]methyl}-1h-indole-2,3-dione
Total Genus 158
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
158
sequence length
447
structure length
447
Chain Sequence
SKISEAVKRARAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAYYEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNLTIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKERFDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEGQKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFETFSHRRSCLVRPLMNDEGLKVRYPPSPA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of indole-2,3-diones as novel class of inhibitors for ALDH isozymes.
rcsb
molecule tags Oxidoreductase/inhibitor
source organism Homo sapiens
molecule keywords Aldehyde dehydrogenase
total genus 158
structure length 447
sequence length 447
chains with identical sequence B
ec nomenclature ec 1.2.1.5: Aldehyde dehydrogenase (NAD(P)(+)).
pdb deposition date 2013-06-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00171 Aldedh Aldehyde dehydrogenase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.309.10 Alpha Beta 3-Layer(aba) Sandwich Aldehyde Dehydrogenase; Chain A, domain 2 Aldehyde Dehydrogenase; Chain A, domain 2 4l1oA02
3.40.605.10 Alpha Beta 3-Layer(aba) Sandwich Aldehyde Dehydrogenase; Chain A, domain 1 Aldehyde Dehydrogenase; Chain A, domain 1 4l1oA01
2W8NA 4X4LA 1KY8A 3RHMA 4NMJA 4YWVA 5L2MA 4I25A 3SZ9A 2J40A 5DBVA 2EJ6A 1UZBA 2ILUA 1T90A 1CW3A 2OPXA 3K9DA 4LH0A 1NZWA 4ZVWA 4GO3A 2O2QA 4MPBA 4WPNA 1UXTA 4ZWLA 3TY7A 4WJ9A 4QN2A 4FR8A 1UXVA 4I26A 4U3WA 3MY7A 3QANA 5DIBA 2BJKA 5EXFA 4YWEA 4L1OA 3U4JA 2XDRA 5KLLA 4X0TA 4NMKA 4QJEA 4LGZA 3RHLA 2BHPA 3ROSA 3V9GA 3V9HA 1O02A 1O9JA 4LH1A 4MPYA 4QTOA 5EEBA 3SZBA 4PXLA 4E4GA 4NEAA 5KLNA 1UXNA 1WNBA 4K57A 3VZ1A 3EK1A 4ZVYA 3R64A 4GHKA 3RHHA 4ZZ7A 2BHQA 2IY6A 1A4ZA 1NZZA 4KNAA 4I3TA 5J7IA 4ZUKA 5EUYA 3INJA 4QETA 1ZUMA 4YWUA 1UXQA 2QE0A 1O04A 4NU9A 4OU2A 2WMEA 2Y5DA 5KLKA 5FHZA 1AD3A 4GNZA 4IYMA 4KWFA 3IWKA 4QGKA 3JZ4A 3JU8A 2D4EA 4NPIA 2EJDA 3RHOA 2W8PA 4KWGA 4QYJA 4OE4A 3IWJA 3PQAA 2W8RA 5EYUA 3RJLA 4OE5A 3VZ3A 4C3SA 5AC0A 4I1WA 4L2OA 5DRUA 2J6LA 3RHDA 3N83A 3ETFA 5EK6A 1O01A 3RHJA 4A0MA 2BJAA 4PZ2A 1QI6A 4LEMA 1A4SA 4LIHA 3I44A 3V9JA 4WB9A 2EITA 4I3WA 5AC2A 1O05A 4Q92A 4V3FA 3RH9A 4ITAA 4OE2A 2Y53A 1BI9A 4GO4A 4IDSA 1EUHA 3RHPA 3INLA 1UXRA 4X0UA 4O6RA 3V4CA 2O2PA 2VROA 4I2RA 4JDCA 4JZ6A 2W8QA 3N80A 4NS3A 2EHUA 2WMEC 1O00A 4GO2A 4ITBA 4QJEB 3K2WA 2ONPA 1BXSA 3R31A 2EIWA 2EJLA 2JG7A 2ONNA 4LH3A 4PXLB 4PXNA 3RHQA 5A2DD 4DNGA 4E3XA 5A2DA 2Y52A 1UXPA 3PRLA 1EZ0A 2Y51A 2ID2A 2H5GA 2HG2A 4O5HA 4WP7A 5JRYA 2ONOA 4OUBA 5KLMA 4ZVXA 4IHIA 4CBBA 2W8OA 3SZAA 4H80A 1VLUA 2VLEA 3EFVA 4X2QA 3V9KA 3ZQAA 1QI1A 5AC1A 4I8PA 5KJ5A 4V3FC 2EHQA 1WNDA 4LH2A 5J6BA 1UXUA 3V9IA 1NZXA 4IT9A 4I8QA 4ZXUA 3VZ2A 4FQFA 4V37A 2ONMA 3V9LA 2WOXA 3VZ0A 4I3VA 4H7NA 4IDMA 2IMPA 1O20A 4I9BA 5J78A 1AG8A 2ESDA 3B4WA 3RHRA 5L2OA 3N82A 1BPWA 2EIIA 4OHTA 2EUHA 5A2DC 5L13A 4I3UA 5KLOA 4CAZA 4H73A 4ZULA 4GO0A 5EZ4A 1EYYA 2O2RA 5F2CA 2J5NA 4JBEA 5KF0A 4QF6A 5EKCA 4OGDA 4I3XA 4DALA 4OE6A 3N81A 4F3XA 5L2NA 5ABMA
chains in the Genus database with same CATH superfamily
2W8NA 4X4LA 1KY8A 3RHMA 4NMJA 4YWVA 5L2MA 4I25A 3SZ9A 2J40A 5DBVA 2EJ6A 1UZBA 2ILUA 1T90A 1CW3A 2OPXA 3K9DA 4LH0A 1NZWA 4ZVWA 4GO3A 2O2QA 4MPBA 4WPNA 1UXTA 4ZWLA 3TY7A 4WJ9A 4QN2A 4FR8A 1UXVA 4I26A 4U3WA 3MY7A 3QANA 5DIBA 2BJKA 5EXFA 4YWEA 4L1OA 3U4JA 2XDRA 5KLLA 4X0TA 4NMKA 4QJEA 4LGZA 3RHLA 2BHPA 3ROSA 3V9GA 3V9HA 1O02A 1O9JA 4LH1A 4MPYA 4QTOA 5EEBA 3SZBA 4PXLA 4E4GA 4NEAA 5KLNA 1UXNA 1WNBA 4K57A 3VZ1A 3EK1A 4ZVYA 3R64A 4GHKA 3RHHA 4ZZ7A 2BHQA 2IY6A 1A4ZA 1NZZA 4KNAA 4I3TA 5J7IA 4ZUKA 5EUYA 3INJA 4QETA 1ZUMA 4YWUA 1UXQA 2QE0A 1O04A 4NU9A 4OU2A 2WMEA 2Y5DA 5KLKA 5FHZA 1AD3A 4GNZA 4IYMA 4KWFA 3IWKA 4QGKA 3JZ4A 3JU8A 2D4EA 4NPIA 2EJDA 3RHOA 2W8PA 4KWGA 4QYJA 4OE4A 3IWJA 3PQAA 2W8RA 5EYUA 3RJLA 4OE5A 3VZ3A 4C3SA 5AC0A 4I1WA 4L2OA 5DRUA 2J6LA 3RHDA 3N83A 3ETFA 5EK6A 1O01A 3RHJA 4A0MA 2BJAA 4PZ2A 1QI6A 4LEMA 1A4SA 4LIHA 3I44A 3V9JA 4WB9A 2EITA 4I3WA 5AC2A 1O05A 4Q92A 4V3FA 3RH9A 4ITAA 4OE2A 2Y53A 1BI9A 4GO4A 4IDSA 1EUHA 3RHPA 3INLA 1UXRA 4X0UA 4O6RA 3V4CA 2O2PA 2VROA 4I2RA 4JDCA 4JZ6A 2W8QA 3N80A 4NS3A 2EHUA 2WMEC 1O00A 4GO2A 4ITBA 4QJEB 3K2WA 2ONPA 1BXSA 3R31A 2EIWA 2EJLA 2JG7A 2ONNA 4LH3A 4PXLB 4PXNA 3RHQA 5A2DD 4DNGA 4E3XA 5A2DA 2Y52A 1UXPA 3PRLA 1EZ0A 2Y51A 2ID2A 2H5GA 2HG2A 4O5HA 4WP7A 5JRYA 2ONOA 4OUBA 5KLMA 4ZVXA 4IHIA 4CBBA 2W8OA 3SZAA 4H80A 1VLUA 2VLEA 3EFVA 4X2QA 3V9KA 3ZQAA 1QI1A 5AC1A 4I8PA 5KJ5A 4V3FC 2EHQA 1WNDA 4LH2A 5J6BA 1UXUA 3V9IA 1NZXA 4IT9A 4I8QA 4ZXUA 3VZ2A 4FQFA 4V37A 2ONMA 3V9LA 2WOXA 3VZ0A 4I3VA 4H7NA 4IDMA 2IMPA 1O20A 4I9BA 5J78A 1AG8A 2ESDA 3B4WA 3RHRA 5L2OA 3N82A 1BPWA 2EIIA 4OHTA 2EUHA 5A2DC 5L13A 4I3UA 5KLOA 4CAZA 4H73A 4ZULA 4GO0A 5EZ4A 1EYYA 2O2RA 5F2CA 2J5NA 4JBEA 5KF0A 4QF6A 5EKCA 4OGDA 4I3XA 4DALA 4OE6A 3N81A 4F3XA 5L2NA 5ABMA
chains in the Genus database with same CATH topology
2W8NA 4X4LA 1KY8A 3RHMA 4NMJA 4YWVA 5L2MA 4I25A 3SZ9A 2J40A 5DBVA 2EJ6A 1UZBA 2ILUA 1T90A 1CW3A 2OPXA 3K9DA 4LH0A 1NZWA 4ZVWA 4GO3A 2O2QA 4MPBA 4WPNA 1UXTA 4ZWLA 3TY7A 4WJ9A 4QN2A 4FR8A 1UXVA 4I26A 4U3WA 3MY7A 3QANA 5DIBA 2BJKA 5EXFA 4YWEA 4L1OA 3U4JA 2XDRA 5KLLA 4X0TA 4NMKA 4QJEA 4LGZA 3RHLA 2BHPA 3ROSA 3V9GA 3V9HA 1O02A 1O9JA 4LH1A 4MPYA 4QTOA 5EEBA 3SZBA 4PXLA 4E4GA 4NEAA 5KLNA 1UXNA 1WNBA 4K57A 3VZ1A 3EK1A 4ZVYA 3R64A 4GHKA 3RHHA 4ZZ7A 2BHQA 2IY6A 1A4ZA 1NZZA 4KNAA 4I3TA 5J7IA 4ZUKA 5EUYA 3INJA 4QETA 1ZUMA 4YWUA 1UXQA 2QE0A 1O04A 4NU9A 4OU2A 2WMEA 2Y5DA 5KLKA 5FHZA 1AD3A 4GNZA 4IYMA 4KWFA 3IWKA 4QGKA 3JZ4A 3JU8A 2D4EA 4NPIA 2EJDA 3RHOA 2W8PA 4KWGA 4QYJA 4OE4A 3IWJA 3PQAA 2W8RA 5EYUA 3RJLA 4OE5A 3VZ3A 4C3SA 5AC0A 4I1WA 4L2OA 5DRUA 2J6LA 3RHDA 3N83A 3ETFA 5EK6A 1O01A 3RHJA 4A0MA 2BJAA 4PZ2A 1QI6A 4LEMA 1A4SA 4LIHA 3I44A 3V9JA 4WB9A 2EITA 4I3WA 5AC2A 1O05A 4Q92A 4V3FA 3RH9A 4ITAA 4OE2A 2Y53A 1BI9A 4GO4A 4IDSA 1EUHA 3RHPA 3INLA 1UXRA 4X0UA 4O6RA 3V4CA 2O2PA 2VROA 4I2RA 4JDCA 4JZ6A 2W8QA 3N80A 4NS3A 2EHUA 2WMEC 1O00A 4GO2A 4ITBA 4QJEB 3K2WA 2ONPA 1BXSA 3R31A 2EIWA 2EJLA 2JG7A 2ONNA 4LH3A 4PXLB 4PXNA 3RHQA 5A2DD 4DNGA 4E3XA 5A2DA 2Y52A 1UXPA 3PRLA 1EZ0A 2Y51A 2ID2A 2H5GA 2HG2A 4O5HA 4WP7A 5JRYA 2ONOA 4OUBA 5KLMA 4ZVXA 4IHIA 4CBBA 2W8OA 3SZAA 4H80A 1VLUA 2VLEA 3EFVA 4X2QA 3V9KA 3ZQAA 1QI1A 5AC1A 4I8PA 5KJ5A 4V3FC 2EHQA 1WNDA 4LH2A 5J6BA 1UXUA 3V9IA 1NZXA 4IT9A 4I8QA 4ZXUA 3VZ2A 4FQFA 4V37A 2ONMA 3V9LA 2WOXA 3VZ0A 4I3VA 4H7NA 4IDMA 2IMPA 1O20A 4I9BA 5J78A 1AG8A 2ESDA 3B4WA 3RHRA 5L2OA 3N82A 1BPWA 2EIIA 4OHTA 2EUHA 5A2DC 5L13A 4I3UA 5KLOA 4CAZA 4H73A 4ZULA 4GO0A 5EZ4A 1EYYA 2O2RA 5F2CA 2J5NA 4JBEA 5KF0A 4QF6A 5EKCA 4OGDA 4I3XA 4DALA 4OE6A 3N81A 4F3XA 5L2NA 5ABMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2W8N A;  4X4L A;  1KY8 A;  3RHM A;  4NMJ A;  4YWV A;  5L2M A;  4I25 A;  3SZ9 A;  2J40 A;  5DBV A;  2EJ6 A;  1UZB A;  2ILU A;  1T90 A;  1CW3 A;  2OPX A;  3K9D A;  4LH0 A;  1NZW A;  4ZVW A;  4GO3 A;  2O2Q A;  4MPB A;  4WPN A;  1UXT A;  4ZWL A;  3TY7 A;  4WJ9 A;  4QN2 A;  4FR8 A;  1UXV A;  4I26 A;  4U3W A;  3MY7 A;  3QAN A;  5DIB A;  2BJK A;  5EXF A;  4YWE A;  4L1O A;  3U4J A;  2XDR A;  5KLL A;  4X0T A;  4NMK A;  4QJE A;  4LGZ A;  3RHL A;  2BHP A;  3ROS A;  3V9G A;  3V9H A;  1O02 A;  1O9J A;  4LH1 A;  4MPY A;  4QTO A;  5EEB A;  3SZB A;  4PXL A;  4E4G A;  4NEA A;  5KLN A;  1UXN A;  1WNB A;  4K57 A;  3VZ1 A;  3EK1 A;  4ZVY A;  3R64 A;  4GHK A;  3RHH A;  4ZZ7 A;  2BHQ A;  2IY6 A;  1A4Z A;  1NZZ A;  4KNA A;  4I3T A;  5J7I A;  4ZUK A;  5EUY A;  3INJ A;  4QET A;  1ZUM A;  4YWU A;  1UXQ A;  2QE0 A;  1O04 A;  4NU9 A;  4OU2 A;  2WME A;  2Y5D A;  5KLK A;  5FHZ A;  1AD3 A;  4GNZ A;  4IYM A;  4KWF A;  3IWK A;  4QGK A;  3JZ4 A;  3JU8 A;  2D4E A;  4NPI A;  2EJD A;  3RHO A;  2W8P A;  4KWG A;  4QYJ A;  4OE4 A;  3IWJ A;  3PQA A;  2W8R A;  5EYU A;  3RJL A;  4OE5 A;  3VZ3 A;  4C3S A;  5AC0 A;  4I1W A;  4L2O A;  5DRU A;  2J6L A;  3RHD A;  3N83 A;  3ETF A;  5EK6 A;  1O01 A;  3RHJ A;  4A0M A;  2BJA A;  4PZ2 A;  1QI6 A;  4LEM A;  1A4S A;  4LIH A;  3I44 A;  3V9J A;  4WB9 A;  2EIT A;  4I3W A;  5AC2 A;  1O05 A;  4Q92 A;  4V3F A;  3RH9 A;  4ITA A;  4OE2 A;  2Y53 A;  1BI9 A;  4GO4 A;  4IDS A;  1EUH A;  3RHP A;  3INL A;  1UXR A;  4X0U A;  4O6R A;  3V4C A;  2O2P A;  2VRO A;  4I2R A;  4JDC A;  4JZ6 A;  2W8Q A;  3N80 A;  4NS3 A;  2EHU A;  2WME C;  1O00 A;  4GO2 A;  4ITB A;  4QJE B;  3K2W A;  2ONP A;  1BXS A;  3R31 A;  2EIW A;  2EJL A;  2JG7 A;  2ONN A;  4LH3 A;  4PXL B;  4PXN A;  3RHQ A;  5A2D D;  4DNG A;  4E3X A;  5A2D A;  2Y52 A;  1UXP A;  3PRL A;  1EZ0 A;  2Y51 A;  2ID2 A;  2H5G A;  2HG2 A;  4O5H A;  4WP7 A;  5JRY A;  2ONO A;  4OUB A;  5KLM A;  4ZVX A;  4IHI A;  4CBB A;  2W8O A;  3SZA A;  4H80 A;  1VLU A;  2VLE A;  3EFV A;  4X2Q A;  3V9K A;  3ZQA A;  1QI1 A;  5AC1 A;  4I8P A;  5KJ5 A;  4V3F C;  2EHQ A;  1WND A;  4LH2 A;  5J6B A;  1UXU A;  3V9I A;  1NZX A;  4IT9 A;  4I8Q A;  4ZXU A;  3VZ2 A;  4FQF A;  4V37 A;  2ONM A;  3V9L A;  2WOX A;  3VZ0 A;  4I3V A;  4H7N A;  4IDM A;  2IMP A;  1O20 A;  4I9B A;  5J78 A;  1AG8 A;  2ESD A;  3B4W A;  3RHR A;  5L2O A;  3N82 A;  1BPW A;  2EII A;  4OHT A;  2EUH A;  5A2D C;  5L13 A;  4I3U A;  5KLO A;  4CAZ A;  4H73 A;  4ZUL A;  4GO0 A;  5EZ4 A;  1EYY A;  2O2R A;  5F2C A;  2J5N A;  4JBE A;  5KF0 A;  4QF6 A;  5EKC A;  4OGD A;  4I3X A;  4DAL A;  4OE6 A;  3N81 A;  4F3X A;  5L2N A;  5ABM A; 
#chains in the Genus database with same CATH topology
 2W8N A;  4X4L A;  1KY8 A;  3RHM A;  4NMJ A;  4YWV A;  5L2M A;  4I25 A;  3SZ9 A;  2J40 A;  5DBV A;  2EJ6 A;  1UZB A;  2ILU A;  1T90 A;  1CW3 A;  2OPX A;  3K9D A;  4LH0 A;  1NZW A;  4ZVW A;  4GO3 A;  2O2Q A;  4MPB A;  4WPN A;  1UXT A;  4ZWL A;  3TY7 A;  4WJ9 A;  4QN2 A;  4FR8 A;  1UXV A;  4I26 A;  4U3W A;  3MY7 A;  3QAN A;  5DIB A;  2BJK A;  5EXF A;  4YWE A;  4L1O A;  3U4J A;  2XDR A;  5KLL A;  4X0T A;  4NMK A;  4QJE A;  4LGZ A;  3RHL A;  2BHP A;  3ROS A;  3V9G A;  3V9H A;  1O02 A;  1O9J A;  4LH1 A;  4MPY A;  4QTO A;  5EEB A;  3SZB A;  4PXL A;  4E4G A;  4NEA A;  5KLN A;  1UXN A;  1WNB A;  4K57 A;  3VZ1 A;  3EK1 A;  4ZVY A;  3R64 A;  4GHK A;  3RHH A;  4ZZ7 A;  2BHQ A;  2IY6 A;  1A4Z A;  1NZZ A;  4KNA A;  4I3T A;  5J7I A;  4ZUK A;  5EUY A;  3INJ A;  4QET A;  1ZUM A;  4YWU A;  1UXQ A;  2QE0 A;  1O04 A;  4NU9 A;  4OU2 A;  2WME A;  2Y5D A;  5KLK A;  5FHZ A;  1AD3 A;  4GNZ A;  4IYM A;  4KWF A;  3IWK A;  4QGK A;  3JZ4 A;  3JU8 A;  2D4E A;  4NPI A;  2EJD A;  3RHO A;  2W8P A;  4KWG A;  4QYJ A;  4OE4 A;  3IWJ A;  3PQA A;  2W8R A;  5EYU A;  3RJL A;  4OE5 A;  3VZ3 A;  4C3S A;  5AC0 A;  4I1W A;  4L2O A;  5DRU A;  2J6L A;  3RHD A;  3N83 A;  3ETF A;  5EK6 A;  1O01 A;  3RHJ A;  4A0M A;  2BJA A;  4PZ2 A;  1QI6 A;  4LEM A;  1A4S A;  4LIH A;  3I44 A;  3V9J A;  4WB9 A;  2EIT A;  4I3W A;  5AC2 A;  1O05 A;  4Q92 A;  4V3F A;  3RH9 A;  4ITA A;  4OE2 A;  2Y53 A;  1BI9 A;  4GO4 A;  4IDS A;  1EUH A;  3RHP A;  3INL A;  1UXR A;  4X0U A;  4O6R A;  3V4C A;  2O2P A;  2VRO A;  4I2R A;  4JDC A;  4JZ6 A;  2W8Q A;  3N80 A;  4NS3 A;  2EHU A;  2WME C;  1O00 A;  4GO2 A;  4ITB A;  4QJE B;  3K2W A;  2ONP A;  1BXS A;  3R31 A;  2EIW A;  2EJL A;  2JG7 A;  2ONN A;  4LH3 A;  4PXL B;  4PXN A;  3RHQ A;  5A2D D;  4DNG A;  4E3X A;  5A2D A;  2Y52 A;  1UXP A;  3PRL A;  1EZ0 A;  2Y51 A;  2ID2 A;  2H5G A;  2HG2 A;  4O5H A;  4WP7 A;  5JRY A;  2ONO A;  4OUB A;  5KLM A;  4ZVX A;  4IHI A;  4CBB A;  2W8O A;  3SZA A;  4H80 A;  1VLU A;  2VLE A;  3EFV A;  4X2Q A;  3V9K A;  3ZQA A;  1QI1 A;  5AC1 A;  4I8P A;  5KJ5 A;  4V3F C;  2EHQ A;  1WND A;  4LH2 A;  5J6B A;  1UXU A;  3V9I A;  1NZX A;  4IT9 A;  4I8Q A;  4ZXU A;  3VZ2 A;  4FQF A;  4V37 A;  2ONM A;  3V9L A;  2WOX A;  3VZ0 A;  4I3V A;  4H7N A;  4IDM A;  2IMP A;  1O20 A;  4I9B A;  5J78 A;  1AG8 A;  2ESD A;  3B4W A;  3RHR A;  5L2O A;  3N82 A;  1BPW A;  2EII A;  4OHT A;  2EUH A;  5A2D C;  5L13 A;  4I3U A;  5KLO A;  4CAZ A;  4H73 A;  4ZUL A;  4GO0 A;  5EZ4 A;  1EYY A;  2O2R A;  5F2C A;  2J5N A;  4JBE A;  5KF0 A;  4QF6 A;  5EKC A;  4OGD A;  4I3X A;  4DAL A;  4OE6 A;  3N81 A;  4F3X A;  5L2N A;  5ABM A; 
#chains in the Genus database with same CATH homology
 2W8N A;  4X4L A;  1KY8 A;  3RHM A;  4NMJ A;  4YWV A;  5L2M A;  4I25 A;  3SZ9 A;  2J40 A;  5DBV A;  2EJ6 A;  1UZB A;  2ILU A;  1T90 A;  1CW3 A;  2OPX A;  3K9D A;  4LH0 A;  1NZW A;  4ZVW A;  4GO3 A;  2O2Q A;  4MPB A;  4WPN A;  1UXT A;  4ZWL A;  3TY7 A;  4WJ9 A;  4QN2 A;  4FR8 A;  1UXV A;  4I26 A;  4U3W A;  3MY7 A;  3QAN A;  5DIB A;  2BJK A;  5EXF A;  4YWE A;  4L1O A;  3U4J A;  2XDR A;  5KLL A;  4X0T A;  4NMK A;  4QJE A;  4LGZ A;  3RHL A;  2BHP A;  3ROS A;  3V9G A;  3V9H A;  1O02 A;  1O9J A;  4LH1 A;  4MPY A;  4QTO A;  5EEB A;  3SZB A;  4PXL A;  4E4G A;  4NEA A;  5KLN A;  1UXN A;  1WNB A;  4K57 A;  3VZ1 A;  3EK1 A;  4ZVY A;  3R64 A;  4GHK A;  3RHH A;  4ZZ7 A;  2BHQ A;  2IY6 A;  1A4Z A;  1NZZ A;  4KNA A;  4I3T A;  5J7I A;  4ZUK A;  5EUY A;  3INJ A;  4QET A;  1ZUM A;  4YWU A;  1UXQ A;  2QE0 A;  1O04 A;  4NU9 A;  4OU2 A;  2WME A;  2Y5D A;  5KLK A;  5FHZ A;  1AD3 A;  4GNZ A;  4IYM A;  4KWF A;  3IWK A;  4QGK A;  3JZ4 A;  3JU8 A;  2D4E A;  4NPI A;  2EJD A;  3RHO A;  2W8P A;  4KWG A;  4QYJ A;  4OE4 A;  3IWJ A;  3PQA A;  2W8R A;  5EYU A;  3RJL A;  4OE5 A;  3VZ3 A;  4C3S A;  5AC0 A;  4I1W A;  4L2O A;  5DRU A;  2J6L A;  3RHD A;  3N83 A;  3ETF A;  5EK6 A;  1O01 A;  3RHJ A;  4A0M A;  2BJA A;  4PZ2 A;  1QI6 A;  4LEM A;  1A4S A;  4LIH A;  3I44 A;  3V9J A;  4WB9 A;  2EIT A;  4I3W A;  5AC2 A;  1O05 A;  4Q92 A;  4V3F A;  3RH9 A;  4ITA A;  4OE2 A;  2Y53 A;  1BI9 A;  4GO4 A;  4IDS A;  1EUH A;  3RHP A;  3INL A;  1UXR A;  4X0U A;  4O6R A;  3V4C A;  2O2P A;  2VRO A;  4I2R A;  4JDC A;  4JZ6 A;  2W8Q A;  3N80 A;  4NS3 A;  2EHU A;  2WME C;  1O00 A;  4GO2 A;  4ITB A;  4QJE B;  3K2W A;  2ONP A;  1BXS A;  3R31 A;  2EIW A;  2EJL A;  2JG7 A;  2ONN A;  4LH3 A;  4PXL B;  4PXN A;  3RHQ A;  5A2D D;  4DNG A;  4E3X A;  5A2D A;  2Y52 A;  1UXP A;  3PRL A;  1EZ0 A;  2Y51 A;  2ID2 A;  2H5G A;  2HG2 A;  4O5H A;  4WP7 A;  5JRY A;  2ONO A;  4OUB A;  5KLM A;  4ZVX A;  4IHI A;  4CBB A;  2W8O A;  3SZA A;  4H80 A;  1VLU A;  2VLE A;  3EFV A;  4X2Q A;  3V9K A;  3ZQA A;  1QI1 A;  5AC1 A;  4I8P A;  5KJ5 A;  4V3F C;  2EHQ A;  1WND A;  4LH2 A;  5J6B A;  1UXU A;  3V9I A;  1NZX A;  4IT9 A;  4I8Q A;  4ZXU A;  3VZ2 A;  4FQF A;  4V37 A;  2ONM A;  3V9L A;  2WOX A;  3VZ0 A;  4I3V A;  4H7N A;  4IDM A;  2IMP A;  1O20 A;  4I9B A;  5J78 A;  1AG8 A;  2ESD A;  3B4W A;  3RHR A;  5L2O A;  3N82 A;  1BPW A;  2EII A;  4OHT A;  2EUH A;  5A2D C;  5L13 A;  4I3U A;  5KLO A;  4CAZ A;  4H73 A;  4ZUL A;  4GO0 A;  5EZ4 A;  1EYY A;  2O2R A;  5F2C A;  2J5N A;  4JBE A;  5KF0 A;  4QF6 A;  5EKC A;  4OGD A;  4I3X A;  4DAL A;  4OE6 A;  3N81 A;  4F3X A;  5L2N A;  5ABM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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