4LH2A

Structure of mouse 1-pyrroline-5-carboxylate dehydrogenase (aldh4a1) complexed with succinate
Total Genus 190
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
190
sequence length
534
structure length
534
Chain Sequence
LKVANEPILAFSQGSPERDALQKALKDLKGQTEAIPCVVGDEEVWTSDIQYQLSPFNHAHKVAKFCYADKALLNRAIDAALAARKEWDLKPMADRAQVFLKAADMLSGPRRAEVLAKTMVGQGKTVIQAEIDAAAELIDFFRFNAKFAVELEGEQPISVPPSTNHTVYRGLEGFVAAISPFNFTAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPADGPTFGDTVTSSEHLCGINFTGSVPTFKHLWRQVAQNLDRFRTFPRLAGECGGKNFHFVHSSADVDSVVSGTLRSAFEYGGQKCSACSRLYVPKSLWPQIKGRLLEEHSRIKVGDPAEDFGTFFSAVIDAKAFARIKKWLEHARSSPSLSILAGGQCNESVGYYVEPCIIESKDPQEPIMKEEIFGPVLTVYVYPDDKYRETLKLVDSTTSYGLTGAVFAQDKAIVQEATRMLRNAAGNFYINDKSTGSVVGQQPFGGARASGTNDKPGGPHYILRWTSPQVIKETHKPLGDWRYSYMQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis of substrate selectivity of Delta (1)-pyrroline-5-carboxylate dehydrogenase (ALDH4A1): Semialdehyde chain length.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Mus musculus
molecule keywords Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial
total genus 190
structure length 534
sequence length 534
chains with identical sequence B
ec nomenclature ec 1.2.1.88: L-glutamate gamma-semialdehyde dehydrogenase.
pdb deposition date 2013-06-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00171 Aldedh Aldehyde dehydrogenase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.309.10 Alpha Beta 3-Layer(aba) Sandwich Aldehyde Dehydrogenase; Chain A, domain 2 Aldehyde Dehydrogenase; Chain A, domain 2 4lh2A02
3.40.605.10 Alpha Beta 3-Layer(aba) Sandwich Aldehyde Dehydrogenase; Chain A, domain 1 Aldehyde Dehydrogenase; Chain A, domain 1 4lh2A01
4CAZA 4NEAA 2EJLA 3V9JA 4PXLA 5EYUA 4ZVWA 4QGKA 1NZZA 5F2CA 1O20A 4MPBA 4O5HA 4A0MA 4LIHA 1AG8A 4ZVYA 3U4JA 4I8QA 4I1WA 5DIBA 2H5GA 3INJA 5AC0A 4Q92A 2JG7A 3SZ9A 1QI6A 2WMEA 4NS3A 4OE4A 4DNGA 5L2MA 4X0UA 5KLMA 4MPYA 4ITAA 3VZ0A 5A2DA 1ZUMA 4E3XA 2VLEA 4QTOA 3RHOA 4KNAA 4F3XA 4JZ6A 4YWUA 4I3VA 2OPXA 4LH1A 2XDRA 3V9GA 5KLNA 2IY6A 1O05A 2EUHA 5J7IA 4QN2A 5EXFA 4CBBA 4H7NA 1BI9A 5EZ4A 1UXNA 3V4CA 2ONOA 4H73A 3VZ2A 4H80A 2ESDA 4IDMA 1O01A 2EIWA 4ZVXA 4GO2A 3VZ3A 4LEMA 5L2NA 3INLA 3RHDA 3RHJA 3R64A 3V9KA 5J78A 1EUHA 4NPIA 2EHUA 2WMEC 1UXTA 3I44A 4GO4A 4L1OA 5A2DC 4WP7A 4X2QA 4I9BA 4LH3A 4GO3A 3V9IA 3ZQAA 3R31A 5DBVA 5AC2A 5DRUA 2W8QA 2W8PA 4KWGA 4LH0A 4O6RA 4OE2A 2ONMA 4OE5A 3N80A 4I3TA 4LH2A 3RHHA 3K2WA 2IMPA 1VLUA 2QE0A 5EUYA 2W8OA 3K9DA 2BJAA 4I2RA 1UZBA 2W8NA 5KLOA 4E4GA 4V3FC 2BHPA 3V9LA 4JBEA 1BXSA 4WB9A 5ABMA 5KJ5A 4QJEB 5EKCA 4I3XA 4I3UA 4GNZA 5FHZA 1CW3A 3JU8A 4OGDA 4K57A 4V3FA 4ZULA 4I3WA 4FQFA 5KLKA 3RHQA 3VZ1A 1NZWA 5EK6A 2BJKA 2Y51A 3PQAA 4YWVA 4PXNA 2ID2A 3QANA 4DALA 3B4WA 4U3WA 4OUBA 2EJ6A 1T90A 3IWJA 2EJDA 4KWFA 4NMJA 3RHMA 3RJLA 3SZBA 2VROA 1A4ZA 2HG2A 3EK1A 2WOXA 3N83A 1WNDA 4NMKA 2J40A 2BHQA 1UXVA 2W8RA 4C3SA 5L13A 2ONNA 4QF6A 3PRLA 4PXLB 1WNBA 5KLLA 2ONPA 4IT9A 4WJ9A 4L2OA 3EFVA 4OHTA 4X0TA 4ZWLA 5JRYA 3V9HA 4QETA 2J6LA 1BPWA 2EITA 3JZ4A 5A2DD 2EHQA 1UXPA 4ZZ7A 5AC1A 4IYMA 1O9JA 1A4SA 1KY8A 1QI1A 4V37A 2Y53A 4GHKA 1O00A 4IHIA 4ZUKA 1O04A 2EIIA 4ZXUA 1UXQA 4IDSA 4OE6A 4FR8A 4I26A 3RHRA 3TY7A 1EYYA 1UXUA 4OU2A 4QJEA 1EZ0A 2J5NA 5EEBA 4I8PA 4WPNA 2Y52A 3SZAA 1NZXA 3IWKA 2O2PA 4X4LA 5L2OA 5KF0A 4JDCA 4LGZA 2D4EA 3RHLA 3ROSA 4I25A 4ITBA 1AD3A 4NU9A 3N82A 4GO0A 3MY7A 5J6BA 2O2QA 3RHPA 3N81A 2ILUA 1O02A 3RH9A 3ETFA 4PZ2A 2O2RA 2Y5DA 4YWEA 1UXRA 4QYJA
chains in the Genus database with same CATH superfamily
4CAZA 4NEAA 2EJLA 3V9JA 4PXLA 5EYUA 4ZVWA 4QGKA 1NZZA 5F2CA 1O20A 4MPBA 4O5HA 4A0MA 4LIHA 1AG8A 4ZVYA 3U4JA 4I8QA 4I1WA 5DIBA 2H5GA 3INJA 5AC0A 4Q92A 2JG7A 3SZ9A 1QI6A 2WMEA 4NS3A 4OE4A 4DNGA 5L2MA 4X0UA 5KLMA 4MPYA 4ITAA 3VZ0A 5A2DA 1ZUMA 4E3XA 2VLEA 4QTOA 3RHOA 4KNAA 4F3XA 4JZ6A 4YWUA 4I3VA 2OPXA 4LH1A 2XDRA 3V9GA 5KLNA 2IY6A 1O05A 2EUHA 5J7IA 4QN2A 5EXFA 4CBBA 4H7NA 1BI9A 5EZ4A 1UXNA 3V4CA 2ONOA 4H73A 3VZ2A 4H80A 2ESDA 4IDMA 1O01A 2EIWA 4ZVXA 4GO2A 3VZ3A 4LEMA 5L2NA 3INLA 3RHDA 3RHJA 3R64A 3V9KA 5J78A 1EUHA 4NPIA 2EHUA 2WMEC 1UXTA 3I44A 4GO4A 4L1OA 5A2DC 4WP7A 4X2QA 4I9BA 4LH3A 4GO3A 3V9IA 3ZQAA 3R31A 5DBVA 5AC2A 5DRUA 2W8QA 2W8PA 4KWGA 4LH0A 4O6RA 4OE2A 2ONMA 4OE5A 3N80A 4I3TA 4LH2A 3RHHA 3K2WA 2IMPA 1VLUA 2QE0A 5EUYA 2W8OA 3K9DA 2BJAA 4I2RA 1UZBA 2W8NA 5KLOA 4E4GA 4V3FC 2BHPA 3V9LA 4JBEA 1BXSA 4WB9A 5ABMA 5KJ5A 4QJEB 5EKCA 4I3XA 4I3UA 4GNZA 5FHZA 1CW3A 3JU8A 4OGDA 4K57A 4V3FA 4ZULA 4I3WA 4FQFA 5KLKA 3RHQA 3VZ1A 1NZWA 5EK6A 2BJKA 2Y51A 3PQAA 4YWVA 4PXNA 2ID2A 3QANA 4DALA 3B4WA 4U3WA 4OUBA 2EJ6A 1T90A 3IWJA 2EJDA 4KWFA 4NMJA 3RHMA 3RJLA 3SZBA 2VROA 1A4ZA 2HG2A 3EK1A 2WOXA 3N83A 1WNDA 4NMKA 2J40A 2BHQA 1UXVA 2W8RA 4C3SA 5L13A 2ONNA 4QF6A 3PRLA 4PXLB 1WNBA 5KLLA 2ONPA 4IT9A 4WJ9A 4L2OA 3EFVA 4OHTA 4X0TA 4ZWLA 5JRYA 3V9HA 4QETA 2J6LA 1BPWA 2EITA 3JZ4A 5A2DD 2EHQA 1UXPA 4ZZ7A 5AC1A 4IYMA 1O9JA 1A4SA 1KY8A 1QI1A 4V37A 2Y53A 4GHKA 1O00A 4IHIA 4ZUKA 1O04A 2EIIA 4ZXUA 1UXQA 4IDSA 4OE6A 4FR8A 4I26A 3RHRA 3TY7A 1EYYA 1UXUA 4OU2A 4QJEA 1EZ0A 2J5NA 5EEBA 4I8PA 4WPNA 2Y52A 3SZAA 1NZXA 3IWKA 2O2PA 4X4LA 5L2OA 5KF0A 4JDCA 4LGZA 2D4EA 3RHLA 3ROSA 4I25A 4ITBA 1AD3A 4NU9A 3N82A 4GO0A 3MY7A 5J6BA 2O2QA 3RHPA 3N81A 2ILUA 1O02A 3RH9A 3ETFA 4PZ2A 2O2RA 2Y5DA 4YWEA 1UXRA 4QYJA
chains in the Genus database with same CATH topology
4CAZA 4NEAA 2EJLA 3V9JA 4PXLA 5EYUA 4ZVWA 4QGKA 1NZZA 5F2CA 1O20A 4MPBA 4O5HA 4A0MA 4LIHA 1AG8A 4ZVYA 3U4JA 4I8QA 4I1WA 5DIBA 2H5GA 3INJA 5AC0A 4Q92A 2JG7A 3SZ9A 1QI6A 2WMEA 4NS3A 4OE4A 4DNGA 5L2MA 4X0UA 5KLMA 4MPYA 4ITAA 3VZ0A 5A2DA 1ZUMA 4E3XA 2VLEA 4QTOA 3RHOA 4KNAA 4F3XA 4JZ6A 4YWUA 4I3VA 2OPXA 4LH1A 2XDRA 3V9GA 5KLNA 2IY6A 1O05A 2EUHA 5J7IA 4QN2A 5EXFA 4CBBA 4H7NA 1BI9A 5EZ4A 1UXNA 3V4CA 2ONOA 4H73A 3VZ2A 4H80A 2ESDA 4IDMA 1O01A 2EIWA 4ZVXA 4GO2A 3VZ3A 4LEMA 5L2NA 3INLA 3RHDA 3RHJA 3R64A 3V9KA 5J78A 1EUHA 4NPIA 2EHUA 2WMEC 1UXTA 3I44A 4GO4A 4L1OA 5A2DC 4WP7A 4X2QA 4I9BA 4LH3A 4GO3A 3V9IA 3ZQAA 3R31A 5DBVA 5AC2A 5DRUA 2W8QA 2W8PA 4KWGA 4LH0A 4O6RA 4OE2A 2ONMA 4OE5A 3N80A 4I3TA 4LH2A 3RHHA 3K2WA 2IMPA 1VLUA 2QE0A 5EUYA 2W8OA 3K9DA 2BJAA 4I2RA 1UZBA 2W8NA 5KLOA 4E4GA 4V3FC 2BHPA 3V9LA 4JBEA 1BXSA 4WB9A 5ABMA 5KJ5A 4QJEB 5EKCA 4I3XA 4I3UA 4GNZA 5FHZA 1CW3A 3JU8A 4OGDA 4K57A 4V3FA 4ZULA 4I3WA 4FQFA 5KLKA 3RHQA 3VZ1A 1NZWA 5EK6A 2BJKA 2Y51A 3PQAA 4YWVA 4PXNA 2ID2A 3QANA 4DALA 3B4WA 4U3WA 4OUBA 2EJ6A 1T90A 3IWJA 2EJDA 4KWFA 4NMJA 3RHMA 3RJLA 3SZBA 2VROA 1A4ZA 2HG2A 3EK1A 2WOXA 3N83A 1WNDA 4NMKA 2J40A 2BHQA 1UXVA 2W8RA 4C3SA 5L13A 2ONNA 4QF6A 3PRLA 4PXLB 1WNBA 5KLLA 2ONPA 4IT9A 4WJ9A 4L2OA 3EFVA 4OHTA 4X0TA 4ZWLA 5JRYA 3V9HA 4QETA 2J6LA 1BPWA 2EITA 3JZ4A 5A2DD 2EHQA 1UXPA 4ZZ7A 5AC1A 4IYMA 1O9JA 1A4SA 1KY8A 1QI1A 4V37A 2Y53A 4GHKA 1O00A 4IHIA 4ZUKA 1O04A 2EIIA 4ZXUA 1UXQA 4IDSA 4OE6A 4FR8A 4I26A 3RHRA 3TY7A 1EYYA 1UXUA 4OU2A 4QJEA 1EZ0A 2J5NA 5EEBA 4I8PA 4WPNA 2Y52A 3SZAA 1NZXA 3IWKA 2O2PA 4X4LA 5L2OA 5KF0A 4JDCA 4LGZA 2D4EA 3RHLA 3ROSA 4I25A 4ITBA 1AD3A 4NU9A 3N82A 4GO0A 3MY7A 5J6BA 2O2QA 3RHPA 3N81A 2ILUA 1O02A 3RH9A 3ETFA 4PZ2A 2O2RA 2Y5DA 4YWEA 1UXRA 4QYJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4CAZ A;  4NEA A;  2EJL A;  3V9J A;  4PXL A;  5EYU A;  4ZVW A;  4QGK A;  1NZZ A;  5F2C A;  1O20 A;  4MPB A;  4O5H A;  4A0M A;  4LIH A;  1AG8 A;  4ZVY A;  3U4J A;  4I8Q A;  4I1W A;  5DIB A;  2H5G A;  3INJ A;  5AC0 A;  4Q92 A;  2JG7 A;  3SZ9 A;  1QI6 A;  2WME A;  4NS3 A;  4OE4 A;  4DNG A;  5L2M A;  4X0U A;  5KLM A;  4MPY A;  4ITA A;  3VZ0 A;  5A2D A;  1ZUM A;  4E3X A;  2VLE A;  4QTO A;  3RHO A;  4KNA A;  4F3X A;  4JZ6 A;  4YWU A;  4I3V A;  2OPX A;  4LH1 A;  2XDR A;  3V9G A;  5KLN A;  2IY6 A;  1O05 A;  2EUH A;  5J7I A;  4QN2 A;  5EXF A;  4CBB A;  4H7N A;  1BI9 A;  5EZ4 A;  1UXN A;  3V4C A;  2ONO A;  4H73 A;  3VZ2 A;  4H80 A;  2ESD A;  4IDM A;  1O01 A;  2EIW A;  4ZVX A;  4GO2 A;  3VZ3 A;  4LEM A;  5L2N A;  3INL A;  3RHD A;  3RHJ A;  3R64 A;  3V9K A;  5J78 A;  1EUH A;  4NPI A;  2EHU A;  2WME C;  1UXT A;  3I44 A;  4GO4 A;  4L1O A;  5A2D C;  4WP7 A;  4X2Q A;  4I9B A;  4LH3 A;  4GO3 A;  3V9I A;  3ZQA A;  3R31 A;  5DBV A;  5AC2 A;  5DRU A;  2W8Q A;  2W8P A;  4KWG A;  4LH0 A;  4O6R A;  4OE2 A;  2ONM A;  4OE5 A;  3N80 A;  4I3T A;  4LH2 A;  3RHH A;  3K2W A;  2IMP A;  1VLU A;  2QE0 A;  5EUY A;  2W8O A;  3K9D A;  2BJA A;  4I2R A;  1UZB A;  2W8N A;  5KLO A;  4E4G A;  4V3F C;  2BHP A;  3V9L A;  4JBE A;  1BXS A;  4WB9 A;  5ABM A;  5KJ5 A;  4QJE B;  5EKC A;  4I3X A;  4I3U A;  4GNZ A;  5FHZ A;  1CW3 A;  3JU8 A;  4OGD A;  4K57 A;  4V3F A;  4ZUL A;  4I3W A;  4FQF A;  5KLK A;  3RHQ A;  3VZ1 A;  1NZW A;  5EK6 A;  2BJK A;  2Y51 A;  3PQA A;  4YWV A;  4PXN A;  2ID2 A;  3QAN A;  4DAL A;  3B4W A;  4U3W A;  4OUB A;  2EJ6 A;  1T90 A;  3IWJ A;  2EJD A;  4KWF A;  4NMJ A;  3RHM A;  3RJL A;  3SZB A;  2VRO A;  1A4Z A;  2HG2 A;  3EK1 A;  2WOX A;  3N83 A;  1WND A;  4NMK A;  2J40 A;  2BHQ A;  1UXV A;  2W8R A;  4C3S A;  5L13 A;  2ONN A;  4QF6 A;  3PRL A;  4PXL B;  1WNB A;  5KLL A;  2ONP A;  4IT9 A;  4WJ9 A;  4L2O A;  3EFV A;  4OHT A;  4X0T A;  4ZWL A;  5JRY A;  3V9H A;  4QET A;  2J6L A;  1BPW A;  2EIT A;  3JZ4 A;  5A2D D;  2EHQ A;  1UXP A;  4ZZ7 A;  5AC1 A;  4IYM A;  1O9J A;  1A4S A;  1KY8 A;  1QI1 A;  4V37 A;  2Y53 A;  4GHK A;  1O00 A;  4IHI A;  4ZUK A;  1O04 A;  2EII A;  4ZXU A;  1UXQ A;  4IDS A;  4OE6 A;  4FR8 A;  4I26 A;  3RHR A;  3TY7 A;  1EYY A;  1UXU A;  4OU2 A;  4QJE A;  1EZ0 A;  2J5N A;  5EEB A;  4I8P A;  4WPN A;  2Y52 A;  3SZA A;  1NZX A;  3IWK A;  2O2P A;  4X4L A;  5L2O A;  5KF0 A;  4JDC A;  4LGZ A;  2D4E A;  3RHL A;  3ROS A;  4I25 A;  4ITB A;  1AD3 A;  4NU9 A;  3N82 A;  4GO0 A;  3MY7 A;  5J6B A;  2O2Q A;  3RHP A;  3N81 A;  2ILU A;  1O02 A;  3RH9 A;  3ETF A;  4PZ2 A;  2O2R A;  2Y5D A;  4YWE A;  1UXR A;  4QYJ A; 
#chains in the Genus database with same CATH topology
 4CAZ A;  4NEA A;  2EJL A;  3V9J A;  4PXL A;  5EYU A;  4ZVW A;  4QGK A;  1NZZ A;  5F2C A;  1O20 A;  4MPB A;  4O5H A;  4A0M A;  4LIH A;  1AG8 A;  4ZVY A;  3U4J A;  4I8Q A;  4I1W A;  5DIB A;  2H5G A;  3INJ A;  5AC0 A;  4Q92 A;  2JG7 A;  3SZ9 A;  1QI6 A;  2WME A;  4NS3 A;  4OE4 A;  4DNG A;  5L2M A;  4X0U A;  5KLM A;  4MPY A;  4ITA A;  3VZ0 A;  5A2D A;  1ZUM A;  4E3X A;  2VLE A;  4QTO A;  3RHO A;  4KNA A;  4F3X A;  4JZ6 A;  4YWU A;  4I3V A;  2OPX A;  4LH1 A;  2XDR A;  3V9G A;  5KLN A;  2IY6 A;  1O05 A;  2EUH A;  5J7I A;  4QN2 A;  5EXF A;  4CBB A;  4H7N A;  1BI9 A;  5EZ4 A;  1UXN A;  3V4C A;  2ONO A;  4H73 A;  3VZ2 A;  4H80 A;  2ESD A;  4IDM A;  1O01 A;  2EIW A;  4ZVX A;  4GO2 A;  3VZ3 A;  4LEM A;  5L2N A;  3INL A;  3RHD A;  3RHJ A;  3R64 A;  3V9K A;  5J78 A;  1EUH A;  4NPI A;  2EHU A;  2WME C;  1UXT A;  3I44 A;  4GO4 A;  4L1O A;  5A2D C;  4WP7 A;  4X2Q A;  4I9B A;  4LH3 A;  4GO3 A;  3V9I A;  3ZQA A;  3R31 A;  5DBV A;  5AC2 A;  5DRU A;  2W8Q A;  2W8P A;  4KWG A;  4LH0 A;  4O6R A;  4OE2 A;  2ONM A;  4OE5 A;  3N80 A;  4I3T A;  4LH2 A;  3RHH A;  3K2W A;  2IMP A;  1VLU A;  2QE0 A;  5EUY A;  2W8O A;  3K9D A;  2BJA A;  4I2R A;  1UZB A;  2W8N A;  5KLO A;  4E4G A;  4V3F C;  2BHP A;  3V9L A;  4JBE A;  1BXS A;  4WB9 A;  5ABM A;  5KJ5 A;  4QJE B;  5EKC A;  4I3X A;  4I3U A;  4GNZ A;  5FHZ A;  1CW3 A;  3JU8 A;  4OGD A;  4K57 A;  4V3F A;  4ZUL A;  4I3W A;  4FQF A;  5KLK A;  3RHQ A;  3VZ1 A;  1NZW A;  5EK6 A;  2BJK A;  2Y51 A;  3PQA A;  4YWV A;  4PXN A;  2ID2 A;  3QAN A;  4DAL A;  3B4W A;  4U3W A;  4OUB A;  2EJ6 A;  1T90 A;  3IWJ A;  2EJD A;  4KWF A;  4NMJ A;  3RHM A;  3RJL A;  3SZB A;  2VRO A;  1A4Z A;  2HG2 A;  3EK1 A;  2WOX A;  3N83 A;  1WND A;  4NMK A;  2J40 A;  2BHQ A;  1UXV A;  2W8R A;  4C3S A;  5L13 A;  2ONN A;  4QF6 A;  3PRL A;  4PXL B;  1WNB A;  5KLL A;  2ONP A;  4IT9 A;  4WJ9 A;  4L2O A;  3EFV A;  4OHT A;  4X0T A;  4ZWL A;  5JRY A;  3V9H A;  4QET A;  2J6L A;  1BPW A;  2EIT A;  3JZ4 A;  5A2D D;  2EHQ A;  1UXP A;  4ZZ7 A;  5AC1 A;  4IYM A;  1O9J A;  1A4S A;  1KY8 A;  1QI1 A;  4V37 A;  2Y53 A;  4GHK A;  1O00 A;  4IHI A;  4ZUK A;  1O04 A;  2EII A;  4ZXU A;  1UXQ A;  4IDS A;  4OE6 A;  4FR8 A;  4I26 A;  3RHR A;  3TY7 A;  1EYY A;  1UXU A;  4OU2 A;  4QJE A;  1EZ0 A;  2J5N A;  5EEB A;  4I8P A;  4WPN A;  2Y52 A;  3SZA A;  1NZX A;  3IWK A;  2O2P A;  4X4L A;  5L2O A;  5KF0 A;  4JDC A;  4LGZ A;  2D4E A;  3RHL A;  3ROS A;  4I25 A;  4ITB A;  1AD3 A;  4NU9 A;  3N82 A;  4GO0 A;  3MY7 A;  5J6B A;  2O2Q A;  3RHP A;  3N81 A;  2ILU A;  1O02 A;  3RH9 A;  3ETF A;  4PZ2 A;  2O2R A;  2Y5D A;  4YWE A;  1UXR A;  4QYJ A; 
#chains in the Genus database with same CATH homology
 4CAZ A;  4NEA A;  2EJL A;  3V9J A;  4PXL A;  5EYU A;  4ZVW A;  4QGK A;  1NZZ A;  5F2C A;  1O20 A;  4MPB A;  4O5H A;  4A0M A;  4LIH A;  1AG8 A;  4ZVY A;  3U4J A;  4I8Q A;  4I1W A;  5DIB A;  2H5G A;  3INJ A;  5AC0 A;  4Q92 A;  2JG7 A;  3SZ9 A;  1QI6 A;  2WME A;  4NS3 A;  4OE4 A;  4DNG A;  5L2M A;  4X0U A;  5KLM A;  4MPY A;  4ITA A;  3VZ0 A;  5A2D A;  1ZUM A;  4E3X A;  2VLE A;  4QTO A;  3RHO A;  4KNA A;  4F3X A;  4JZ6 A;  4YWU A;  4I3V A;  2OPX A;  4LH1 A;  2XDR A;  3V9G A;  5KLN A;  2IY6 A;  1O05 A;  2EUH A;  5J7I A;  4QN2 A;  5EXF A;  4CBB A;  4H7N A;  1BI9 A;  5EZ4 A;  1UXN A;  3V4C A;  2ONO A;  4H73 A;  3VZ2 A;  4H80 A;  2ESD A;  4IDM A;  1O01 A;  2EIW A;  4ZVX A;  4GO2 A;  3VZ3 A;  4LEM A;  5L2N A;  3INL A;  3RHD A;  3RHJ A;  3R64 A;  3V9K A;  5J78 A;  1EUH A;  4NPI A;  2EHU A;  2WME C;  1UXT A;  3I44 A;  4GO4 A;  4L1O A;  5A2D C;  4WP7 A;  4X2Q A;  4I9B A;  4LH3 A;  4GO3 A;  3V9I A;  3ZQA A;  3R31 A;  5DBV A;  5AC2 A;  5DRU A;  2W8Q A;  2W8P A;  4KWG A;  4LH0 A;  4O6R A;  4OE2 A;  2ONM A;  4OE5 A;  3N80 A;  4I3T A;  4LH2 A;  3RHH A;  3K2W A;  2IMP A;  1VLU A;  2QE0 A;  5EUY A;  2W8O A;  3K9D A;  2BJA A;  4I2R A;  1UZB A;  2W8N A;  5KLO A;  4E4G A;  4V3F C;  2BHP A;  3V9L A;  4JBE A;  1BXS A;  4WB9 A;  5ABM A;  5KJ5 A;  4QJE B;  5EKC A;  4I3X A;  4I3U A;  4GNZ A;  5FHZ A;  1CW3 A;  3JU8 A;  4OGD A;  4K57 A;  4V3F A;  4ZUL A;  4I3W A;  4FQF A;  5KLK A;  3RHQ A;  3VZ1 A;  1NZW A;  5EK6 A;  2BJK A;  2Y51 A;  3PQA A;  4YWV A;  4PXN A;  2ID2 A;  3QAN A;  4DAL A;  3B4W A;  4U3W A;  4OUB A;  2EJ6 A;  1T90 A;  3IWJ A;  2EJD A;  4KWF A;  4NMJ A;  3RHM A;  3RJL A;  3SZB A;  2VRO A;  1A4Z A;  2HG2 A;  3EK1 A;  2WOX A;  3N83 A;  1WND A;  4NMK A;  2J40 A;  2BHQ A;  1UXV A;  2W8R A;  4C3S A;  5L13 A;  2ONN A;  4QF6 A;  3PRL A;  4PXL B;  1WNB A;  5KLL A;  2ONP A;  4IT9 A;  4WJ9 A;  4L2O A;  3EFV A;  4OHT A;  4X0T A;  4ZWL A;  5JRY A;  3V9H A;  4QET A;  2J6L A;  1BPW A;  2EIT A;  3JZ4 A;  5A2D D;  2EHQ A;  1UXP A;  4ZZ7 A;  5AC1 A;  4IYM A;  1O9J A;  1A4S A;  1KY8 A;  1QI1 A;  4V37 A;  2Y53 A;  4GHK A;  1O00 A;  4IHI A;  4ZUK A;  1O04 A;  2EII A;  4ZXU A;  1UXQ A;  4IDS A;  4OE6 A;  4FR8 A;  4I26 A;  3RHR A;  3TY7 A;  1EYY A;  1UXU A;  4OU2 A;  4QJE A;  1EZ0 A;  2J5N A;  5EEB A;  4I8P A;  4WPN A;  2Y52 A;  3SZA A;  1NZX A;  3IWK A;  2O2P A;  4X4L A;  5L2O A;  5KF0 A;  4JDC A;  4LGZ A;  2D4E A;  3RHL A;  3ROS A;  4I25 A;  4ITB A;  1AD3 A;  4NU9 A;  3N82 A;  4GO0 A;  3MY7 A;  5J6B A;  2O2Q A;  3RHP A;  3N81 A;  2ILU A;  1O02 A;  3RH9 A;  3ETF A;  4PZ2 A;  2O2R A;  2Y5D A;  4YWE A;  1UXR A;  4QYJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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