4YKDA

Crystal structure of truncated cerebral cavernous malformation 2 c-terminal adaptor domain
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
84
structure length
84
Chain Sequence
ASATELLQDYMLTLRTKLSSQEIQQFAALLHEYRNGASIHEFCINLRQLYGDSRKFLLLGLRPFIPEKDSQHFENFLETIGVKD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Insights into the Molecular Recognition between Cerebral Cavernous Malformation 2 and Mitogen-Activated Protein Kinase Kinase Kinase 3
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Malcavernin
total genus 33
structure length 84
sequence length 84
ec nomenclature
pdb deposition date 2015-03-04
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1160.20 Mainly Alpha Up-down Bundle Paired amphipathic helix 2 (pah2 repeat) Paired amphipathic helix 2 (pah2 repeat) 4ykdA00
4YL6A 2LSRA 4FQNA 4YKDA 4Y5OA 2KBRA 4YKCA 3K1RA 2KBQA 5F3XA
chains in the Genus database with same CATH superfamily
2F05A 1PD7A 2LD7B 5F3XA 2RMSA 2LSRA 4YKDA 1E91A 2L9SB 4YL6A 2CR7A 2KBRA 2RMRA 1S5RB 1G1EB 1S5QB 4FQNA 2CZYA 4Y5OA 4YKCA 3K1RA 2KBQA
chains in the Genus database with same CATH topology
4YL6A 2LSRA 4FQNA 4YKDA 4Y5OA 2KBRA 4YKCA 3K1RA 2KBQA 5F3XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YL6 A;  2LSR A;  4FQN A;  4YKD A;  4Y5O A;  2KBR A;  4YKC A;  3K1R A;  2KBQ A;  5F3X A; 
#chains in the Genus database with same CATH topology
 2F05 A;  1PD7 A;  2LD7 B;  5F3X A;  2RMS A;  2LSR A;  4YKD A;  1E91 A;  2L9S B;  4YL6 A;  2CR7 A;  2KBR A;  2RMR A;  1S5R B;  1G1E B;  1S5Q B;  4FQN A;  2CZY A;  4Y5O A;  4YKC A;  3K1R A;  2KBQ A; 
#chains in the Genus database with same CATH homology
 4YL6 A;  2LSR A;  4FQN A;  4YKD A;  4Y5O A;  2KBR A;  4YKC A;  3K1R A;  2KBQ A;  5F3X A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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