4YL6A

Crystal structure of truncated cerebral cavernous malformation 2 c-terminal adaptor domain in complex with an internal helix of mitogen-activated protein kinase kinase kinase 3
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
88
structure length
88
Chain Sequence
LSASATELLQDYMLTLRTKLSSQEIQQFAALLHEYRNGASIHEFCINLRQLYGDSRKFLLLGLRPFIPEKDSQHFENFLETIGVKDLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Insights into the Molecular Recognition between Cerebral Cavernous Malformation 2 and Mitogen-Activated Protein Kinase Kinase Kinase 3
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Malcavernin
total genus 33
structure length 88
sequence length 88
ec nomenclature
pdb deposition date 2015-03-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1160.20 Mainly Alpha Up-down Bundle Paired amphipathic helix 2 (pah2 repeat) Paired amphipathic helix 2 (pah2 repeat) 4yl6A00
3K1RA 2KBQA 2KBRA 4YL6A 4YKCA 4YKDA 4FQNA 2LSRA 5F3XA 4Y5OA
chains in the Genus database with same CATH superfamily
2RMSA 2KBQA 4FQNA 1S5RB 2CZYA 3K1RA 2KBRA 4YL6A 2F05A 1G1EB 2LSRA 1PD7A 2RMRA 2L9SB 4YKCA 2CR7A 1S5QB 2LD7B 4YKDA 1E91A 5F3XA 4Y5OA
chains in the Genus database with same CATH topology
3K1RA 2KBQA 2KBRA 4YL6A 4YKCA 4YKDA 4FQNA 2LSRA 5F3XA 4Y5OA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3K1R A;  2KBQ A;  2KBR A;  4YL6 A;  4YKC A;  4YKD A;  4FQN A;  2LSR A;  5F3X A;  4Y5O A; 
#chains in the Genus database with same CATH topology
 2RMS A;  2KBQ A;  4FQN A;  1S5R B;  2CZY A;  3K1R A;  2KBR A;  4YL6 A;  2F05 A;  1G1E B;  2LSR A;  1PD7 A;  2RMR A;  2L9S B;  4YKC A;  2CR7 A;  1S5Q B;  2LD7 B;  4YKD A;  1E91 A;  5F3X A;  4Y5O A; 
#chains in the Genus database with same CATH homology
 3K1R A;  2KBQ A;  2KBR A;  4YL6 A;  4YKC A;  4YKD A;  4FQN A;  2LSR A;  5F3X A;  4Y5O A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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