5C2JA

Complex structure of the gap domain of mgcracgap and cdc42
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
201
structure length
201
Chain Sequence
IGEGMLADFVSQTSPMIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICSLLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHLQRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMSQDIKRQPKVVERLLSLPLEYWSQFMMVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis of G-protein target alternation of MgcRacGAP by phospholylation
rcsb
molecule keywords Rac GTPase-activating protein 1
molecule tags Hydrolase activator/signaling protein
source organism Homo sapiens
total genus 67
structure length 201
sequence length 201
ec nomenclature
pdb deposition date 2015-06-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 5c2jA00
2MBGA 3CXLA 3FK2A 2OVJA 3QISA 1PBWA 2OSAA 2XS6A 1XA6A 5C2JA 3WPQA 3WPSA 5JD0A 3KUQA 2QV2A 3EAPA 1RGPA 1AM4A 2EE5A 5HPYA 1F7CA 5IRCA 3MSXB 2NGRB 1OW3A 5C5SA 3BYIA 1GRNB 2EE4A 1TX4A 3IUGA 3W6RA 5JCPA
chains in the Genus database with same CATH superfamily
2MBGA 3CXLA 3FK2A 2OVJA 3QISA 1PBWA 2OSAA 2XS6A 1XA6A 5C2JA 3WPQA 3WPSA 5JD0A 3KUQA 2QV2A 3EAPA 1RGPA 1AM4A 2EE5A 5HPYA 1F7CA 5IRCA 3MSXB 2NGRB 1OW3A 5C5SA 3BYIA 1GRNB 2EE4A 1TX4A 3IUGA 3W6RA 5JCPA
chains in the Genus database with same CATH topology
2MBGA 3CXLA 3FK2A 2OVJA 3QISA 1PBWA 2OSAA 2XS6A 1XA6A 5C2JA 3WPQA 3WPSA 5JD0A 3KUQA 2QV2A 3EAPA 1RGPA 1AM4A 2EE5A 5HPYA 1F7CA 5IRCA 3MSXB 2NGRB 1OW3A 5C5SA 3BYIA 1GRNB 2EE4A 1TX4A 3IUGA 3W6RA 5JCPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2MBG A;  3CXL A;  3FK2 A;  2OVJ A;  3QIS A;  1PBW A;  2OSA A;  2XS6 A;  1XA6 A;  5C2J A;  3WPQ A;  3WPS A;  5JD0 A;  3KUQ A;  2QV2 A;  3EAP A;  1RGP A;  1AM4 A;  2EE5 A;  5HPY A;  1F7C A;  5IRC A;  3MSX B;  2NGR B;  1OW3 A;  5C5S A;  3BYI A;  1GRN B;  2EE4 A;  1TX4 A;  3IUG A;  3W6R A;  5JCP A; 
#chains in the Genus database with same CATH topology
 2MBG A;  3CXL A;  3FK2 A;  2OVJ A;  3QIS A;  1PBW A;  2OSA A;  2XS6 A;  1XA6 A;  5C2J A;  3WPQ A;  3WPS A;  5JD0 A;  3KUQ A;  2QV2 A;  3EAP A;  1RGP A;  1AM4 A;  2EE5 A;  5HPY A;  1F7C A;  5IRC A;  3MSX B;  2NGR B;  1OW3 A;  5C5S A;  3BYI A;  1GRN B;  2EE4 A;  1TX4 A;  3IUG A;  3W6R A;  5JCP A; 
#chains in the Genus database with same CATH homology
 2MBG A;  3CXL A;  3FK2 A;  2OVJ A;  3QIS A;  1PBW A;  2OSA A;  2XS6 A;  1XA6 A;  5C2J A;  3WPQ A;  3WPS A;  5JD0 A;  3KUQ A;  2QV2 A;  3EAP A;  1RGP A;  1AM4 A;  2EE5 A;  5HPY A;  1F7C A;  5IRC A;  3MSX B;  2NGR B;  1OW3 A;  5C5S A;  3BYI A;  1GRN B;  2EE4 A;  1TX4 A;  3IUG A;  3W6R A;  5JCP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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