5C2JA

Complex structure of the gap domain of mgcracgap and cdc42
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
201
structure length
201
Chain Sequence
IGEGMLADFVSQTSPMIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICSLLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHLQRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMSQDIKRQPKVVERLLSLPLEYWSQFMMVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis of G-protein target alternation of MgcRacGAP by phospholylation
rcsb
molecule tags Hydrolase activator/signaling protein
source organism Homo sapiens
molecule keywords Rac GTPase-activating protein 1
total genus 67
structure length 201
sequence length 201
ec nomenclature
pdb deposition date 2015-06-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 5c2jA00
2XS6A 5C2JA 1PBWA 1F7CA 3QISA 1TX4A 5JCPA 1RGPA 5C5SA 2NGRB 3BYIA 3WPQA 5JD0A 5IRCA 3KUQA 3EAPA 2QV2A 2EE5A 1OW3A 5HPYA 1GRNB 3FK2A 3MSXB 3W6RA 3CXLA 1XA6A 3WPSA 2EE4A 2OSAA 2OVJA 3IUGA 2MBGA 1AM4A
chains in the Genus database with same CATH superfamily
2XS6A 5C2JA 1PBWA 1F7CA 3QISA 1TX4A 5JCPA 1RGPA 5C5SA 2NGRB 3BYIA 3WPQA 5JD0A 5IRCA 3KUQA 3EAPA 2QV2A 2EE5A 1OW3A 5HPYA 1GRNB 3FK2A 3MSXB 3W6RA 3CXLA 1XA6A 3WPSA 2EE4A 2OSAA 2OVJA 3IUGA 2MBGA 1AM4A
chains in the Genus database with same CATH topology
2XS6A 5C2JA 1PBWA 1F7CA 3QISA 1TX4A 5JCPA 1RGPA 5C5SA 2NGRB 3BYIA 3WPQA 5JD0A 5IRCA 3KUQA 3EAPA 2QV2A 2EE5A 1OW3A 5HPYA 1GRNB 3FK2A 3MSXB 3W6RA 3CXLA 1XA6A 3WPSA 2EE4A 2OSAA 2OVJA 3IUGA 2MBGA 1AM4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XS6 A;  5C2J A;  1PBW A;  1F7C A;  3QIS A;  1TX4 A;  5JCP A;  1RGP A;  5C5S A;  2NGR B;  3BYI A;  3WPQ A;  5JD0 A;  5IRC A;  3KUQ A;  3EAP A;  2QV2 A;  2EE5 A;  1OW3 A;  5HPY A;  1GRN B;  3FK2 A;  3MSX B;  3W6R A;  3CXL A;  1XA6 A;  3WPS A;  2EE4 A;  2OSA A;  2OVJ A;  3IUG A;  2MBG A;  1AM4 A; 
#chains in the Genus database with same CATH topology
 2XS6 A;  5C2J A;  1PBW A;  1F7C A;  3QIS A;  1TX4 A;  5JCP A;  1RGP A;  5C5S A;  2NGR B;  3BYI A;  3WPQ A;  5JD0 A;  5IRC A;  3KUQ A;  3EAP A;  2QV2 A;  2EE5 A;  1OW3 A;  5HPY A;  1GRN B;  3FK2 A;  3MSX B;  3W6R A;  3CXL A;  1XA6 A;  3WPS A;  2EE4 A;  2OSA A;  2OVJ A;  3IUG A;  2MBG A;  1AM4 A; 
#chains in the Genus database with same CATH homology
 2XS6 A;  5C2J A;  1PBW A;  1F7C A;  3QIS A;  1TX4 A;  5JCP A;  1RGP A;  5C5S A;  2NGR B;  3BYI A;  3WPQ A;  5JD0 A;  5IRC A;  3KUQ A;  3EAP A;  2QV2 A;  2EE5 A;  1OW3 A;  5HPY A;  1GRN B;  3FK2 A;  3MSX B;  3W6R A;  3CXL A;  1XA6 A;  3WPS A;  2EE4 A;  2OSA A;  2OVJ A;  3IUG A;  2MBG A;  1AM4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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