5HL7H

The crystal structure of the large ribosomal subunit of staphylococcus aureus in complex with lefamulin
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
122
structure length
122
Chain Sequence
MIQQETRLKVADNSGAREVLTIKVLGGSGRKTANIGDVIVCTVKNATPGGVVKKGDVVKAVIVRTKSGVRRNDGSYIKFDENACVIIRDDKGPRGTRIFGPVARELREGNFMKIVSLAPEVL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A novel pleuromutilin antibacterial compound, its binding mode and selectivity mechanism.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2
total genus 24
structure length 122
sequence length 122
ec nomenclature
pdb deposition date 2016-01-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
H PF00238 Ribosomal_L14 Ribosomal protein L14p/L23e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.150.20 Mainly Beta Beta Barrel Ribosomal Protein L14 Ribosomal protein L14 5hl7H00
3CD6K 4WCEH 1VQMK 3OW2J 4UY8K 1YJNK 3CCSK 1WHIA 5GAHL 5GADL 4V19O 4IOCH 1YI2K 5DM7H 5AN9E 1YIJK 3CC7K 1KC8L 1VQ5K 1VQLK 1VQOK 5MLCM 1VQ4K 3CC4K 2ZJPH 4U67H 3DLLH 1YHQK 1W2BJ 4WFBH 1M90L 1KD1L 3I56K 3PIOH 2OTLK 1M1KL 3G6EK 1VQNK 1VQ9K 1K73L 2ZJQH 3I55K 3G4SK 1YJ9K 5JVGH 3CF5H 1QVGJ 5GAEL 3CCVK 4IOAH 3CMEK 4WF9H 5H1SM 4WFNH 3CC2K 3CCMK 3CCRK 3J7ZK 1K8AL 5DM6H 1S72K 2OTJK 1QVFJ 1Q82L 1Q7YL 1VQ8K 1KQSJ 2QA4K 3CCEK 5JVHH 3CXCJ 4WFAH 1VQKK 5HL7H 3J7YL 1VQ7K 3G71K 3CCJK 1VQ6K 1Q81L 1Q86L 3CCUK 1YJWK 1JJ2J 4IO9H 1VQPK 3PIPH 3CMAK 3CPWJ 1K9ML 2ZJRH 3CCQK 1YITK 3CCLK 1N8RL 1NJIL 5GAGL 2QEXK
chains in the Genus database with same CATH superfamily
3CD6K 4WCEH 1VQMK 3OW2J 4UY8K 1YJNK 3CCSK 1WHIA 5GAHL 5GADL 4V19O 4IOCH 1YI2K 5DM7H 5AN9E 1YIJK 3CC7K 1KC8L 1VQ5K 1VQLK 1VQOK 5MLCM 1VQ4K 3CC4K 2ZJPH 4U67H 3DLLH 1YHQK 1W2BJ 4WFBH 1M90L 1KD1L 3I56K 3PIOH 2OTLK 1M1KL 3G6EK 1VQNK 1VQ9K 1K73L 2ZJQH 3I55K 3G4SK 1YJ9K 5JVGH 3CF5H 1QVGJ 5GAEL 3CCVK 4IOAH 3CMEK 4WF9H 5H1SM 4WFNH 3CC2K 3CCMK 3CCRK 3J7ZK 1K8AL 5DM6H 1S72K 2OTJK 1QVFJ 1Q82L 1Q7YL 1VQ8K 1KQSJ 2QA4K 3CCEK 5JVHH 3CXCJ 4WFAH 1VQKK 5HL7H 3J7YL 1VQ7K 3G71K 3CCJK 1VQ6K 1Q81L 1Q86L 3CCUK 1YJWK 1JJ2J 4IO9H 1VQPK 3PIPH 3CMAK 3CPWJ 1K9ML 2ZJRH 3CCQK 1YITK 3CCLK 1N8RL 1NJIL 5GAGL 2QEXK
chains in the Genus database with same CATH topology
3CD6K 4WCEH 1VQMK 3OW2J 4UY8K 1YJNK 3CCSK 1WHIA 5GAHL 5GADL 4V19O 4IOCH 1YI2K 5DM7H 5AN9E 1YIJK 3CC7K 1KC8L 1VQ5K 1VQLK 1VQOK 5MLCM 1VQ4K 3CC4K 2ZJPH 4U67H 3DLLH 1YHQK 1W2BJ 4WFBH 1M90L 1KD1L 3I56K 3PIOH 2OTLK 1M1KL 3G6EK 1VQNK 1VQ9K 1K73L 2ZJQH 3I55K 3G4SK 1YJ9K 5JVGH 3CF5H 1QVGJ 5GAEL 3CCVK 4IOAH 3CMEK 4WF9H 5H1SM 4WFNH 3CC2K 3CCMK 3CCRK 3J7ZK 1K8AL 5DM6H 1S72K 2OTJK 1QVFJ 1Q82L 1Q7YL 1VQ8K 1KQSJ 2QA4K 3CCEK 5JVHH 3CXCJ 4WFAH 1VQKK 5HL7H 3J7YL 1VQ7K 3G71K 3CCJK 1VQ6K 1Q81L 1Q86L 3CCUK 1YJWK 1JJ2J 4IO9H 1VQPK 3PIPH 3CMAK 3CPWJ 1K9ML 2ZJRH 3CCQK 1YITK 3CCLK 1N8RL 1NJIL 5GAGL 2QEXK
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CD6 K;  4WCE H;  1VQM K;  3OW2 J;  4UY8 K;  1YJN K;  3CCS K;  1WHI A;  5GAH L;  5GAD L;  4V19 O;  4IOC H;  1YI2 K;  5DM7 H;  5AN9 E;  1YIJ K;  3CC7 K;  1KC8 L;  1VQ5 K;  1VQL K;  1VQO K;  5MLC M;  1VQ4 K;  3CC4 K;  2ZJP H;  4U67 H;  3DLL H;  1YHQ K;  1W2B J;  4WFB H;  1M90 L;  1KD1 L;  3I56 K;  3PIO H;  2OTL K;  1M1K L;  3G6E K;  1VQN K;  1VQ9 K;  1K73 L;  2ZJQ H;  3I55 K;  3G4S K;  1YJ9 K;  5JVG H;  3CF5 H;  1QVG J;  5GAE L;  3CCV K;  4IOA H;  3CME K;  4WF9 H;  5H1S M;  4WFN H;  3CC2 K;  3CCM K;  3CCR K;  3J7Z K;  1K8A L;  5DM6 H;  1S72 K;  2OTJ K;  1QVF J;  1Q82 L;  1Q7Y L;  1VQ8 K;  1KQS J;  2QA4 K;  3CCE K;  5JVH H;  3CXC J;  4WFA H;  1VQK K;  5HL7 H;  3J7Y L;  1VQ7 K;  3G71 K;  3CCJ K;  1VQ6 K;  1Q81 L;  1Q86 L;  3CCU K;  1YJW K;  1JJ2 J;  4IO9 H;  1VQP K;  3PIP H;  3CMA K;  3CPW J;  1K9M L;  2ZJR H;  3CCQ K;  1YIT K;  3CCL K;  1N8R L;  1NJI L;  5GAG L;  2QEX K; 
#chains in the Genus database with same CATH topology
 3CD6 K;  4WCE H;  1VQM K;  3OW2 J;  4UY8 K;  1YJN K;  3CCS K;  1WHI A;  5GAH L;  5GAD L;  4V19 O;  4IOC H;  1YI2 K;  5DM7 H;  5AN9 E;  1YIJ K;  3CC7 K;  1KC8 L;  1VQ5 K;  1VQL K;  1VQO K;  5MLC M;  1VQ4 K;  3CC4 K;  2ZJP H;  4U67 H;  3DLL H;  1YHQ K;  1W2B J;  4WFB H;  1M90 L;  1KD1 L;  3I56 K;  3PIO H;  2OTL K;  1M1K L;  3G6E K;  1VQN K;  1VQ9 K;  1K73 L;  2ZJQ H;  3I55 K;  3G4S K;  1YJ9 K;  5JVG H;  3CF5 H;  1QVG J;  5GAE L;  3CCV K;  4IOA H;  3CME K;  4WF9 H;  5H1S M;  4WFN H;  3CC2 K;  3CCM K;  3CCR K;  3J7Z K;  1K8A L;  5DM6 H;  1S72 K;  2OTJ K;  1QVF J;  1Q82 L;  1Q7Y L;  1VQ8 K;  1KQS J;  2QA4 K;  3CCE K;  5JVH H;  3CXC J;  4WFA H;  1VQK K;  5HL7 H;  3J7Y L;  1VQ7 K;  3G71 K;  3CCJ K;  1VQ6 K;  1Q81 L;  1Q86 L;  3CCU K;  1YJW K;  1JJ2 J;  4IO9 H;  1VQP K;  3PIP H;  3CMA K;  3CPW J;  1K9M L;  2ZJR H;  3CCQ K;  1YIT K;  3CCL K;  1N8R L;  1NJI L;  5GAG L;  2QEX K; 
#chains in the Genus database with same CATH homology
 3CD6 K;  4WCE H;  1VQM K;  3OW2 J;  4UY8 K;  1YJN K;  3CCS K;  1WHI A;  5GAH L;  5GAD L;  4V19 O;  4IOC H;  1YI2 K;  5DM7 H;  5AN9 E;  1YIJ K;  3CC7 K;  1KC8 L;  1VQ5 K;  1VQL K;  1VQO K;  5MLC M;  1VQ4 K;  3CC4 K;  2ZJP H;  4U67 H;  3DLL H;  1YHQ K;  1W2B J;  4WFB H;  1M90 L;  1KD1 L;  3I56 K;  3PIO H;  2OTL K;  1M1K L;  3G6E K;  1VQN K;  1VQ9 K;  1K73 L;  2ZJQ H;  3I55 K;  3G4S K;  1YJ9 K;  5JVG H;  3CF5 H;  1QVG J;  5GAE L;  3CCV K;  4IOA H;  3CME K;  4WF9 H;  5H1S M;  4WFN H;  3CC2 K;  3CCM K;  3CCR K;  3J7Z K;  1K8A L;  5DM6 H;  1S72 K;  2OTJ K;  1QVF J;  1Q82 L;  1Q7Y L;  1VQ8 K;  1KQS J;  2QA4 K;  3CCE K;  5JVH H;  3CXC J;  4WFA H;  1VQK K;  5HL7 H;  3J7Y L;  1VQ7 K;  3G71 K;  3CCJ K;  1VQ6 K;  1Q81 L;  1Q86 L;  3CCU K;  1YJW K;  1JJ2 J;  4IO9 H;  1VQP K;  3PIP H;  3CMA K;  3CPW J;  1K9M L;  2ZJR H;  3CCQ K;  1YIT K;  3CCL K;  1N8R L;  1NJI L;  5GAG L;  2QEX K; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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