5HPYA

Crystal structure of rhoa.gdp.mgf3-in complex with human myosin 9b rhogap domain
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
203
structure length
192
Chain Sequence
GHFGVCVSVPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDPAAVKLENFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHLPEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCSDPLTSMKDVLKITTCVEMLIKEQMRKYKVKMEEISQL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Noncanonical Myo9b-RhoGAP Accelerates RhoA GTP Hydrolysis by a Dual-Arginine-Finger Mechanism
pubmed doi rcsb
molecule keywords Unconventional myosin-IXb
molecule tags Gene regulation/signaling protein
source organism Homo sapiens
total genus 72
structure length 192
sequence length 203
chains with identical sequence D
ec nomenclature
pdb deposition date 2016-01-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 5hpyA00
3WPQA 2EE5A 1F7CA 2OSAA 2OVJA 3KUQA 3MSXB 3W6RA 5JD0A 3EAPA 2EE4A 1TX4A 3CXLA 5IRCA 5C5SA 2XS6A 5JCPA 1PBWA 2MBGA 5C2JA 1GRNB 1OW3A 1RGPA 2QV2A 5HPYA 3QISA 3BYIA 3IUGA 1AM4A 3WPSA 3FK2A 2NGRB 1XA6A
chains in the Genus database with same CATH superfamily
3WPQA 2EE5A 1F7CA 2OSAA 2OVJA 3KUQA 3MSXB 3W6RA 5JD0A 3EAPA 2EE4A 1TX4A 3CXLA 5IRCA 5C5SA 2XS6A 5JCPA 1PBWA 2MBGA 5C2JA 1GRNB 1OW3A 1RGPA 2QV2A 5HPYA 3QISA 3BYIA 3IUGA 1AM4A 3WPSA 3FK2A 2NGRB 1XA6A
chains in the Genus database with same CATH topology
3WPQA 2EE5A 1F7CA 2OSAA 2OVJA 3KUQA 3MSXB 3W6RA 5JD0A 3EAPA 2EE4A 1TX4A 3CXLA 5IRCA 5C5SA 2XS6A 5JCPA 1PBWA 2MBGA 5C2JA 1GRNB 1OW3A 1RGPA 2QV2A 5HPYA 3QISA 3BYIA 3IUGA 1AM4A 3WPSA 3FK2A 2NGRB 1XA6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3WPQ A;  2EE5 A;  1F7C A;  2OSA A;  2OVJ A;  3KUQ A;  3MSX B;  3W6R A;  5JD0 A;  3EAP A;  2EE4 A;  1TX4 A;  3CXL A;  5IRC A;  5C5S A;  2XS6 A;  5JCP A;  1PBW A;  2MBG A;  5C2J A;  1GRN B;  1OW3 A;  1RGP A;  2QV2 A;  5HPY A;  3QIS A;  3BYI A;  3IUG A;  1AM4 A;  3WPS A;  3FK2 A;  2NGR B;  1XA6 A; 
#chains in the Genus database with same CATH topology
 3WPQ A;  2EE5 A;  1F7C A;  2OSA A;  2OVJ A;  3KUQ A;  3MSX B;  3W6R A;  5JD0 A;  3EAP A;  2EE4 A;  1TX4 A;  3CXL A;  5IRC A;  5C5S A;  2XS6 A;  5JCP A;  1PBW A;  2MBG A;  5C2J A;  1GRN B;  1OW3 A;  1RGP A;  2QV2 A;  5HPY A;  3QIS A;  3BYI A;  3IUG A;  1AM4 A;  3WPS A;  3FK2 A;  2NGR B;  1XA6 A; 
#chains in the Genus database with same CATH homology
 3WPQ A;  2EE5 A;  1F7C A;  2OSA A;  2OVJ A;  3KUQ A;  3MSX B;  3W6R A;  5JD0 A;  3EAP A;  2EE4 A;  1TX4 A;  3CXL A;  5IRC A;  5C5S A;  2XS6 A;  5JCP A;  1PBW A;  2MBG A;  5C2J A;  1GRN B;  1OW3 A;  1RGP A;  2QV2 A;  5HPY A;  3QIS A;  3BYI A;  3IUG A;  1AM4 A;  3WPS A;  3FK2 A;  2NGR B;  1XA6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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