5I0AA

Reca mini intein in complex with cisplatin
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
142
structure length
142
Chain Sequence
CLAEGTRIFDPVTGTTHRIEDVVDGRKPIHVVAAAKDGTLHARPVVSWFDQGTRDVIGLRIAGGAILWATPDHKVLTEYGWRAAGELRKGDRVAVRDVETGELRYSVIREVLPTRRARTFDLEVEELHTLVAEGVVVHACSP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights into protein splicing inhibition by platinum therapeutics as potential anti-microbials
rcsb
molecule tags Splicing
source organism Mycobacterium tuberculosis
molecule keywords Intein
total genus 33
structure length 142
sequence length 142
ec nomenclature
pdb deposition date 2016-02-03
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.16.10 Mainly Beta Beta Complex Endonuclease - Pi-scei; Chain A, domain 1 Hedgehog/Intein (Hint) domain 5i0aA00
3IFJA 1AM2A 1JVAA 3IGDA 2L8LA 4KL6A 2CW8A 1EF0A 1ZD7A 1VDEA 2IN0A 5K08A 4E2TA 4KL5A 4OZ6A 2LWYA 1UM2A 1AT0A 2IN9A 2KEQA 4O1RA 2LCJA 4E2UA 2JMZA 1DFAA 1ZDEA 2IN8A 4O1SA 1LWSA 1DQ3A 2LQMA 2IMZA 5I0AA 2JNQA 1MI8A 1LWTA 3NZMA 1GPPA 2CW7A 4GIGA
chains in the Genus database with same CATH superfamily
3IFJA 1AM2A 1JVAA 3IGDA 2L8LA 4KL6A 2CW8A 1EF0A 1ZD7A 1VDEA 2IN0A 5K08A 4E2TA 4KL5A 4OZ6A 2LWYA 1UM2A 1AT0A 2IN9A 2KEQA 4O1RA 2LCJA 4E2UA 2JMZA 1DFAA 1ZDEA 2IN8A 4O1SA 1LWSA 1DQ3A 2LQMA 2IMZA 5I0AA 2JNQA 1MI8A 1LWTA 3NZMA 1GPPA 4QFQA 2CW7A 4LX3A 4GIGA
chains in the Genus database with same CATH topology
3IFJA 1AM2A 1JVAA 3IGDA 2L8LA 4KL6A 2CW8A 1EF0A 1ZD7A 1VDEA 2IN0A 5K08A 4E2TA 4KL5A 4OZ6A 2LWYA 1UM2A 1AT0A 2IN9A 2KEQA 4O1RA 2LCJA 4E2UA 2JMZA 1DFAA 1ZDEA 2IN8A 4O1SA 1LWSA 1DQ3A 2LQMA 2IMZA 5I0AA 2JNQA 1MI8A 1LWTA 3NZMA 1GPPA 2CW7A 4GIGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3IFJ A;  1AM2 A;  1JVA A;  3IGD A;  2L8L A;  4KL6 A;  2CW8 A;  1EF0 A;  1ZD7 A;  1VDE A;  2IN0 A;  5K08 A;  4E2T A;  4KL5 A;  4OZ6 A;  2LWY A;  1UM2 A;  1AT0 A;  2IN9 A;  2KEQ A;  4O1R A;  2LCJ A;  4E2U A;  2JMZ A;  1DFA A;  1ZDE A;  2IN8 A;  4O1S A;  1LWS A;  1DQ3 A;  2LQM A;  2IMZ A;  5I0A A;  2JNQ A;  1MI8 A;  1LWT A;  3NZM A;  1GPP A;  2CW7 A;  4GIG A; 
#chains in the Genus database with same CATH topology
 3IFJ A;  1AM2 A;  1JVA A;  3IGD A;  2L8L A;  4KL6 A;  2CW8 A;  1EF0 A;  1ZD7 A;  1VDE A;  2IN0 A;  5K08 A;  4E2T A;  4KL5 A;  4OZ6 A;  2LWY A;  1UM2 A;  1AT0 A;  2IN9 A;  2KEQ A;  4O1R A;  2LCJ A;  4E2U A;  2JMZ A;  1DFA A;  1ZDE A;  2IN8 A;  4O1S A;  1LWS A;  1DQ3 A;  2LQM A;  2IMZ A;  5I0A A;  2JNQ A;  1MI8 A;  1LWT A;  3NZM A;  1GPP A;  4QFQ A;  2CW7 A;  4LX3 A;  4GIG A; 
#chains in the Genus database with same CATH homology
 3IFJ A;  1AM2 A;  1JVA A;  3IGD A;  2L8L A;  4KL6 A;  2CW8 A;  1EF0 A;  1ZD7 A;  1VDE A;  2IN0 A;  5K08 A;  4E2T A;  4KL5 A;  4OZ6 A;  2LWY A;  1UM2 A;  1AT0 A;  2IN9 A;  2KEQ A;  4O1R A;  2LCJ A;  4E2U A;  2JMZ A;  1DFA A;  1ZDE A;  2IN8 A;  4O1S A;  1LWS A;  1DQ3 A;  2LQM A;  2IMZ A;  5I0A A;  2JNQ A;  1MI8 A;  1LWT A;  3NZM A;  1GPP A;  2CW7 A;  4GIG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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