5IRCA

P190a gap domain complex with rhoa
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
201
structure length
200
Chain Sequence
AGSWESNYFGVPLTTVVTPEKPIPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQDHNLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYSMQIDLVEAHKINDREQKLHALKEVLKKFPKENHEVFKYVISHLNRVSHNNKVNLMTSENLSICFWPTLMRPDFSSMDALTATRSYQTIIELFIQQPFFFYNR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Deciphering the Molecular and Functional Basis of RHOGAP Family Proteins: A SYSTEMATIC APPROACH TOWARD SELECTIVE INACTIVATION OF RHO FAMILY PROTEINS.
pubmed doi rcsb
molecule keywords Rho GTPase-activating protein 35
molecule tags Protein binding
source organism Rattus norvegicus
total genus 75
structure length 200
sequence length 201
chains with identical sequence B
ec nomenclature
pdb deposition date 2016-03-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 5ircA00
3FK2A 3BYIA 2EE5A 3KUQA 5C5SA 2EE4A 1PBWA 5JCPA 3IUGA 2OVJA 1GRNB 3EAPA 2XS6A 5IRCA 2OSAA 3WPQA 3WPSA 3CXLA 3QISA 1TX4A 2MBGA 2NGRB 5C2JA 1F7CA 2QV2A 3MSXB 5JD0A 3W6RA 1XA6A 1RGPA 5HPYA 1AM4A 1OW3A
chains in the Genus database with same CATH superfamily
3FK2A 3BYIA 2EE5A 3KUQA 5C5SA 2EE4A 1PBWA 5JCPA 3IUGA 2OVJA 1GRNB 3EAPA 2XS6A 5IRCA 2OSAA 3WPQA 3WPSA 3CXLA 3QISA 1TX4A 2MBGA 2NGRB 5C2JA 1F7CA 2QV2A 3MSXB 5JD0A 3W6RA 1XA6A 1RGPA 5HPYA 1AM4A 1OW3A
chains in the Genus database with same CATH topology
3FK2A 3BYIA 2EE5A 3KUQA 5C5SA 2EE4A 1PBWA 5JCPA 3IUGA 2OVJA 1GRNB 3EAPA 2XS6A 5IRCA 2OSAA 3WPQA 3WPSA 3CXLA 3QISA 1TX4A 2MBGA 2NGRB 5C2JA 1F7CA 2QV2A 3MSXB 5JD0A 3W6RA 1XA6A 1RGPA 5HPYA 1AM4A 1OW3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FK2 A;  3BYI A;  2EE5 A;  3KUQ A;  5C5S A;  2EE4 A;  1PBW A;  5JCP A;  3IUG A;  2OVJ A;  1GRN B;  3EAP A;  2XS6 A;  5IRC A;  2OSA A;  3WPQ A;  3WPS A;  3CXL A;  3QIS A;  1TX4 A;  2MBG A;  2NGR B;  5C2J A;  1F7C A;  2QV2 A;  3MSX B;  5JD0 A;  3W6R A;  1XA6 A;  1RGP A;  5HPY A;  1AM4 A;  1OW3 A; 
#chains in the Genus database with same CATH topology
 3FK2 A;  3BYI A;  2EE5 A;  3KUQ A;  5C5S A;  2EE4 A;  1PBW A;  5JCP A;  3IUG A;  2OVJ A;  1GRN B;  3EAP A;  2XS6 A;  5IRC A;  2OSA A;  3WPQ A;  3WPS A;  3CXL A;  3QIS A;  1TX4 A;  2MBG A;  2NGR B;  5C2J A;  1F7C A;  2QV2 A;  3MSX B;  5JD0 A;  3W6R A;  1XA6 A;  1RGP A;  5HPY A;  1AM4 A;  1OW3 A; 
#chains in the Genus database with same CATH homology
 3FK2 A;  3BYI A;  2EE5 A;  3KUQ A;  5C5S A;  2EE4 A;  1PBW A;  5JCP A;  3IUG A;  2OVJ A;  1GRN B;  3EAP A;  2XS6 A;  5IRC A;  2OSA A;  3WPQ A;  3WPS A;  3CXL A;  3QIS A;  1TX4 A;  2MBG A;  2NGR B;  5C2J A;  1F7C A;  2QV2 A;  3MSX B;  5JD0 A;  3W6R A;  1XA6 A;  1RGP A;  5HPY A;  1AM4 A;  1OW3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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