5IRCA

P190a gap domain complex with rhoa
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
201
structure length
200
Chain Sequence
AGSWESNYFGVPLTTVVTPEKPIPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQDHNLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYSMQIDLVEAHKINDREQKLHALKEVLKKFPKENHEVFKYVISHLNRVSHNNKVNLMTSENLSICFWPTLMRPDFSSMDALTATRSYQTIIELFIQQPFFFYNR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Deciphering the Molecular and Functional Basis of RHOGAP Family Proteins: A SYSTEMATIC APPROACH TOWARD SELECTIVE INACTIVATION OF RHO FAMILY PROTEINS.
pubmed doi rcsb
molecule tags Protein binding
source organism Rattus norvegicus
molecule keywords Rho GTPase-activating protein 35
total genus 75
structure length 200
sequence length 201
chains with identical sequence B
ec nomenclature
pdb deposition date 2016-03-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 5ircA00
1OW3A 3QISA 5IRCA 5C2JA 2QV2A 2OSAA 2XS6A 3W6RA 5HPYA 3WPSA 1RGPA 2EE5A 2EE4A 3IUGA 1TX4A 1XA6A 5JCPA 3MSXB 5C5SA 3BYIA 3WPQA 2MBGA 5JD0A 3KUQA 3EAPA 3CXLA 1GRNB 2OVJA 3FK2A 1AM4A 2NGRB 1F7CA 1PBWA
chains in the Genus database with same CATH superfamily
1OW3A 3QISA 5IRCA 5C2JA 2QV2A 2OSAA 2XS6A 3W6RA 5HPYA 3WPSA 1RGPA 2EE5A 2EE4A 3IUGA 1TX4A 1XA6A 5JCPA 3MSXB 5C5SA 3BYIA 3WPQA 2MBGA 5JD0A 3KUQA 3EAPA 3CXLA 1GRNB 2OVJA 3FK2A 1AM4A 2NGRB 1F7CA 1PBWA
chains in the Genus database with same CATH topology
1OW3A 3QISA 5IRCA 5C2JA 2QV2A 2OSAA 2XS6A 3W6RA 5HPYA 3WPSA 1RGPA 2EE5A 2EE4A 3IUGA 1TX4A 1XA6A 5JCPA 3MSXB 5C5SA 3BYIA 3WPQA 2MBGA 5JD0A 3KUQA 3EAPA 3CXLA 1GRNB 2OVJA 3FK2A 1AM4A 2NGRB 1F7CA 1PBWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1OW3 A;  3QIS A;  5IRC A;  5C2J A;  2QV2 A;  2OSA A;  2XS6 A;  3W6R A;  5HPY A;  3WPS A;  1RGP A;  2EE5 A;  2EE4 A;  3IUG A;  1TX4 A;  1XA6 A;  5JCP A;  3MSX B;  5C5S A;  3BYI A;  3WPQ A;  2MBG A;  5JD0 A;  3KUQ A;  3EAP A;  3CXL A;  1GRN B;  2OVJ A;  3FK2 A;  1AM4 A;  2NGR B;  1F7C A;  1PBW A; 
#chains in the Genus database with same CATH topology
 1OW3 A;  3QIS A;  5IRC A;  5C2J A;  2QV2 A;  2OSA A;  2XS6 A;  3W6R A;  5HPY A;  3WPS A;  1RGP A;  2EE5 A;  2EE4 A;  3IUG A;  1TX4 A;  1XA6 A;  5JCP A;  3MSX B;  5C5S A;  3BYI A;  3WPQ A;  2MBG A;  5JD0 A;  3KUQ A;  3EAP A;  3CXL A;  1GRN B;  2OVJ A;  3FK2 A;  1AM4 A;  2NGR B;  1F7C A;  1PBW A; 
#chains in the Genus database with same CATH homology
 1OW3 A;  3QIS A;  5IRC A;  5C2J A;  2QV2 A;  2OSA A;  2XS6 A;  3W6R A;  5HPY A;  3WPS A;  1RGP A;  2EE5 A;  2EE4 A;  3IUG A;  1TX4 A;  1XA6 A;  5JCP A;  3MSX B;  5C5S A;  3BYI A;  3WPQ A;  2MBG A;  5JD0 A;  3KUQ A;  3EAP A;  3CXL A;  1GRN B;  2OVJ A;  3FK2 A;  1AM4 A;  2NGR B;  1F7C A;  1PBW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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