5ABMA

Sheep aldehyde dehydrogenase 1a1
Total Genus 187
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
187
sequence length
494
structure length
494
Chain Sequence
DVPAPLTNLQFKYTKIFINNEWHSSVSGKKFPVFNPATEEKLCEVEEGDKEDVDKAVKAARQAFQIGSPWRTMDASERGRLLNKLADLIERDRLLLATMEAMNGGKLFSNAYLMDLGGCIKTLRYCAGWADKIQGRTIPMDGNFFTYTRSEPVGVCGQIIPWNFPLLMFLWKIGPALSCGNTVVVKPAEQTPLTALHMGSLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAFTGSTEVGKLIKEAAGKSNLKRVSLELGGKSPCIVFADADLDNAVEFAHQGVFYHQGQCCIAASRLFVEESIYDEFVRRSVERAKKYVLGNPLTPGVSQGPQIDKEQYEKILDLIESGKKEGAKLECGGGPWGNKGYFIQPTVFSDVTDDMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGIFTNDIDKAITVSSALQSGTVWVNCYSVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTIKISQKNS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
publication title Structural, Biochemical, and Computational Studies Reveal the Mechanism of Selective Aldehyde Dehydrogenase 1A1 Inhibition by Cytotoxic Duocarmycin Analogues.
pubmed doi rcsb
molecule keywords RETINAL DEHYDROGENASE 1
molecule tags Oxidoreductase
source organism Ovis aries
total genus 187
structure length 494
sequence length 494
chains with identical sequence B, C, D
ec nomenclature ec 1.2.1.36: Retinal dehydrogenase.
pdb deposition date 2015-08-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00171 Aldedh Aldehyde dehydrogenase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.309.10 Alpha Beta 3-Layer(aba) Sandwich Aldehyde Dehydrogenase; Chain A, domain 2 Aldehyde Dehydrogenase; Chain A, domain 2 5abmA02
3.40.605.10 Alpha Beta 3-Layer(aba) Sandwich Aldehyde Dehydrogenase; Chain A, domain 1 Aldehyde Dehydrogenase; Chain A, domain 1 5abmA01
2HG2A 4I9BA 4IDSA 5EXFA 2BHPA 3ZQAA 1EYYA 3VZ1A 1BPWA 1CW3A 2W8RA 4LH2A 4Q92A 3V9JA 4CBBA 1O9JA 2Y53A 4NU9A 2IY6A 4X2QA 1QI1A 3N83A 2J6LA 2W8NA 1UXVA 4JDCA 3INLA 4JZ6A 4NS3A 2BJAA 4O6RA 5J78A 5A2DC 3N82A 4NPIA 4GO3A 3RJLA 2EIWA 5EKCA 2O2RA 5KLNA 4A0MA 4I3VA 3QANA 3PRLA 3SZAA 5KJ5A 4QYJA 5KLOA 3RHOA 1BI9A 2ILUA 3JU8A 5L13A 2ID2A 4I3TA 1O04A 3PQAA 5EEBA 5JRYA 2OPXA 2Y52A 4PXLA 3RHHA 3R31A 1QI6A 3B4WA 1O05A 1UXQA 4NMKA 3SZ9A 5KLKA 4QGKA 4YWUA 1UZBA 1AD3A 2JG7A 3N80A 4X4LA 4E4GA 4MPBA 2EJDA 2W8OA 4NEAA 3K9DA 3IWKA 1NZZA 2Y51A 4L1OA 2EUHA 2IMPA 4NMJA 2VROA 1O00A 1BXSA 1ZUMA 2EJ6A 4X0UA 1UXPA 4KNAA 2J5NA 3V9LA 5KLMA 4DALA 4ZVXA 4ZVWA 4FQFA 4WPNA 2EJLA 5DBVA 3RHDA 4H80A 4I8QA 1UXTA 2D4EA 1A4ZA 4ITBA 4LH0A 2EITA 4WB9A 2H5GA 4ZUKA 4FR8A 3U4JA 2WOXA 4OHTA 5EK6A 3V9GA 5KLLA 4C3SA 3IWJA 1UXNA 4OE6A 4I8PA 3TY7A 4I3UA 5A2DD 2EIIA 4V3FA 1UXUA 2BHQA 3R64A 4I3WA 4QF6A 4YWEA 5J6BA 1EZ0A 2ONPA 4OU2A 4X0TA 5L2OA 1A4SA 4H7NA 4LIHA 2ONMA 5EYUA 3JZ4A 2WMEA 1O02A 4QETA 3RHPA 4LH1A 4OGDA 2VLEA 4U3WA 4DNGA 3VZ3A 4I1WA 4GNZA 5DRUA 1WNDA 4H73A 1WNBA 4ZVYA 4OUBA 5AC0A 3RHLA 3EK1A 5DIBA 1NZWA 2O2PA 5F2CA 2BJKA 3EFVA 1EUHA 3ETFA 2ONOA 4I25A 4IHIA 4WP7A 4PXNA 3V4CA 3VZ0A 2XDRA 5L2NA 4OE2A 4WJ9A 2EHQA 3RHQA 2O2QA 5ABMA 4V3FC 1AG8A 1KY8A 4ITAA 2Y5DA 3MY7A 4K57A 3RHMA 3RHJA 3V9IA 4CAZA 3INJA 3I44A 4YWVA 4IT9A 4GO4A 2WMEC 3V9KA 3N81A 4GO2A 4KWGA 4LH3A 3RH9A 4LEMA 4GO0A 4F3XA 4V37A 4OE5A 1T90A 4PZ2A 5J7IA 4JBEA 5L2MA 5EZ4A 3K2WA 4QJEB 2J40A 4QTOA 4QN2A 3ROSA 3SZBA 4E3XA 5A2DA 4OE4A 2ESDA 5AC2A 4MPYA 4PXLB 5AC1A 2EHUA 4ZULA 2ONNA 1UXRA 4I26A 4ZZ7A 4I3XA 1O01A 4L2OA 2QE0A 5FHZA 3RHRA 3VZ2A 2W8PA 4O5HA 4GHKA 4LGZA 4QJEA 5EUYA 1NZXA 5KF0A 4IYMA 4I2RA 3V9HA 4ZXUA 1VLUA 4KWFA 1O20A 4IDMA 4ZWLA 2W8QA
chains in the Genus database with same CATH superfamily
2HG2A 4I9BA 4IDSA 5EXFA 2BHPA 3ZQAA 1EYYA 3VZ1A 1BPWA 1CW3A 2W8RA 4LH2A 4Q92A 3V9JA 4CBBA 1O9JA 2Y53A 4NU9A 2IY6A 4X2QA 1QI1A 3N83A 2J6LA 2W8NA 1UXVA 4JDCA 3INLA 4JZ6A 4NS3A 2BJAA 4O6RA 5J78A 5A2DC 3N82A 4NPIA 4GO3A 3RJLA 2EIWA 5EKCA 2O2RA 5KLNA 4A0MA 4I3VA 3QANA 3PRLA 3SZAA 5KJ5A 4QYJA 5KLOA 3RHOA 1BI9A 2ILUA 3JU8A 5L13A 2ID2A 4I3TA 1O04A 3PQAA 5EEBA 5JRYA 2OPXA 2Y52A 4PXLA 3RHHA 3R31A 1QI6A 3B4WA 1O05A 1UXQA 4NMKA 3SZ9A 5KLKA 4QGKA 4YWUA 1UZBA 1AD3A 2JG7A 3N80A 4X4LA 4E4GA 4MPBA 2EJDA 2W8OA 4NEAA 3K9DA 3IWKA 1NZZA 2Y51A 4L1OA 2EUHA 2IMPA 4NMJA 2VROA 1O00A 1BXSA 1ZUMA 2EJ6A 4X0UA 1UXPA 4KNAA 2J5NA 3V9LA 5KLMA 4DALA 4ZVXA 4ZVWA 4FQFA 4WPNA 2EJLA 5DBVA 3RHDA 4H80A 4I8QA 1UXTA 2D4EA 1A4ZA 4ITBA 4LH0A 2EITA 4WB9A 2H5GA 4ZUKA 4FR8A 3U4JA 2WOXA 4OHTA 5EK6A 3V9GA 5KLLA 4C3SA 3IWJA 1UXNA 4OE6A 4I8PA 3TY7A 4I3UA 5A2DD 2EIIA 4V3FA 1UXUA 2BHQA 3R64A 4I3WA 4QF6A 4YWEA 5J6BA 1EZ0A 2ONPA 4OU2A 4X0TA 5L2OA 1A4SA 4H7NA 4LIHA 2ONMA 5EYUA 3JZ4A 2WMEA 1O02A 4QETA 3RHPA 4LH1A 4OGDA 2VLEA 4U3WA 4DNGA 3VZ3A 4I1WA 4GNZA 5DRUA 1WNDA 4H73A 1WNBA 4ZVYA 4OUBA 5AC0A 3RHLA 3EK1A 5DIBA 1NZWA 2O2PA 5F2CA 2BJKA 3EFVA 1EUHA 3ETFA 2ONOA 4I25A 4IHIA 4WP7A 4PXNA 3V4CA 3VZ0A 2XDRA 5L2NA 4OE2A 4WJ9A 2EHQA 3RHQA 2O2QA 5ABMA 4V3FC 1AG8A 1KY8A 4ITAA 2Y5DA 3MY7A 4K57A 3RHMA 3RHJA 3V9IA 4CAZA 3INJA 3I44A 4YWVA 4IT9A 4GO4A 2WMEC 3V9KA 3N81A 4GO2A 4KWGA 4LH3A 3RH9A 4LEMA 4GO0A 4F3XA 4V37A 4OE5A 1T90A 4PZ2A 5J7IA 4JBEA 5L2MA 5EZ4A 3K2WA 4QJEB 2J40A 4QTOA 4QN2A 3ROSA 3SZBA 4E3XA 5A2DA 4OE4A 2ESDA 5AC2A 4MPYA 4PXLB 5AC1A 2EHUA 4ZULA 2ONNA 1UXRA 4I26A 4ZZ7A 4I3XA 1O01A 4L2OA 2QE0A 5FHZA 3RHRA 3VZ2A 2W8PA 4O5HA 4GHKA 4LGZA 4QJEA 5EUYA 1NZXA 5KF0A 4IYMA 4I2RA 3V9HA 4ZXUA 1VLUA 4KWFA 1O20A 4IDMA 4ZWLA 2W8QA
chains in the Genus database with same CATH topology
2HG2A 4I9BA 4IDSA 5EXFA 2BHPA 3ZQAA 1EYYA 3VZ1A 1BPWA 1CW3A 2W8RA 4LH2A 4Q92A 3V9JA 4CBBA 1O9JA 2Y53A 4NU9A 2IY6A 4X2QA 1QI1A 3N83A 2J6LA 2W8NA 1UXVA 4JDCA 3INLA 4JZ6A 4NS3A 2BJAA 4O6RA 5J78A 5A2DC 3N82A 4NPIA 4GO3A 3RJLA 2EIWA 5EKCA 2O2RA 5KLNA 4A0MA 4I3VA 3QANA 3PRLA 3SZAA 5KJ5A 4QYJA 5KLOA 3RHOA 1BI9A 2ILUA 3JU8A 5L13A 2ID2A 4I3TA 1O04A 3PQAA 5EEBA 5JRYA 2OPXA 2Y52A 4PXLA 3RHHA 3R31A 1QI6A 3B4WA 1O05A 1UXQA 4NMKA 3SZ9A 5KLKA 4QGKA 4YWUA 1UZBA 1AD3A 2JG7A 3N80A 4X4LA 4E4GA 4MPBA 2EJDA 2W8OA 4NEAA 3K9DA 3IWKA 1NZZA 2Y51A 4L1OA 2EUHA 2IMPA 4NMJA 2VROA 1O00A 1BXSA 1ZUMA 2EJ6A 4X0UA 1UXPA 4KNAA 2J5NA 3V9LA 5KLMA 4DALA 4ZVXA 4ZVWA 4FQFA 4WPNA 2EJLA 5DBVA 3RHDA 4H80A 4I8QA 1UXTA 2D4EA 1A4ZA 4ITBA 4LH0A 2EITA 4WB9A 2H5GA 4ZUKA 4FR8A 3U4JA 2WOXA 4OHTA 5EK6A 3V9GA 5KLLA 4C3SA 3IWJA 1UXNA 4OE6A 4I8PA 3TY7A 4I3UA 5A2DD 2EIIA 4V3FA 1UXUA 2BHQA 3R64A 4I3WA 4QF6A 4YWEA 5J6BA 1EZ0A 2ONPA 4OU2A 4X0TA 5L2OA 1A4SA 4H7NA 4LIHA 2ONMA 5EYUA 3JZ4A 2WMEA 1O02A 4QETA 3RHPA 4LH1A 4OGDA 2VLEA 4U3WA 4DNGA 3VZ3A 4I1WA 4GNZA 5DRUA 1WNDA 4H73A 1WNBA 4ZVYA 4OUBA 5AC0A 3RHLA 3EK1A 5DIBA 1NZWA 2O2PA 5F2CA 2BJKA 3EFVA 1EUHA 3ETFA 2ONOA 4I25A 4IHIA 4WP7A 4PXNA 3V4CA 3VZ0A 2XDRA 5L2NA 4OE2A 4WJ9A 2EHQA 3RHQA 2O2QA 5ABMA 4V3FC 1AG8A 1KY8A 4ITAA 2Y5DA 3MY7A 4K57A 3RHMA 3RHJA 3V9IA 4CAZA 3INJA 3I44A 4YWVA 4IT9A 4GO4A 2WMEC 3V9KA 3N81A 4GO2A 4KWGA 4LH3A 3RH9A 4LEMA 4GO0A 4F3XA 4V37A 4OE5A 1T90A 4PZ2A 5J7IA 4JBEA 5L2MA 5EZ4A 3K2WA 4QJEB 2J40A 4QTOA 4QN2A 3ROSA 3SZBA 4E3XA 5A2DA 4OE4A 2ESDA 5AC2A 4MPYA 4PXLB 5AC1A 2EHUA 4ZULA 2ONNA 1UXRA 4I26A 4ZZ7A 4I3XA 1O01A 4L2OA 2QE0A 5FHZA 3RHRA 3VZ2A 2W8PA 4O5HA 4GHKA 4LGZA 4QJEA 5EUYA 1NZXA 5KF0A 4IYMA 4I2RA 3V9HA 4ZXUA 1VLUA 4KWFA 1O20A 4IDMA 4ZWLA 2W8QA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2HG2 A;  4I9B A;  4IDS A;  5EXF A;  2BHP A;  3ZQA A;  1EYY A;  3VZ1 A;  1BPW A;  1CW3 A;  2W8R A;  4LH2 A;  4Q92 A;  3V9J A;  4CBB A;  1O9J A;  2Y53 A;  4NU9 A;  2IY6 A;  4X2Q A;  1QI1 A;  3N83 A;  2J6L A;  2W8N A;  1UXV A;  4JDC A;  3INL A;  4JZ6 A;  4NS3 A;  2BJA A;  4O6R A;  5J78 A;  5A2D C;  3N82 A;  4NPI A;  4GO3 A;  3RJL A;  2EIW A;  5EKC A;  2O2R A;  5KLN A;  4A0M A;  4I3V A;  3QAN A;  3PRL A;  3SZA A;  5KJ5 A;  4QYJ A;  5KLO A;  3RHO A;  1BI9 A;  2ILU A;  3JU8 A;  5L13 A;  2ID2 A;  4I3T A;  1O04 A;  3PQA A;  5EEB A;  5JRY A;  2OPX A;  2Y52 A;  4PXL A;  3RHH A;  3R31 A;  1QI6 A;  3B4W A;  1O05 A;  1UXQ A;  4NMK A;  3SZ9 A;  5KLK A;  4QGK A;  4YWU A;  1UZB A;  1AD3 A;  2JG7 A;  3N80 A;  4X4L A;  4E4G A;  4MPB A;  2EJD A;  2W8O A;  4NEA A;  3K9D A;  3IWK A;  1NZZ A;  2Y51 A;  4L1O A;  2EUH A;  2IMP A;  4NMJ A;  2VRO A;  1O00 A;  1BXS A;  1ZUM A;  2EJ6 A;  4X0U A;  1UXP A;  4KNA A;  2J5N A;  3V9L A;  5KLM A;  4DAL A;  4ZVX A;  4ZVW A;  4FQF A;  4WPN A;  2EJL A;  5DBV A;  3RHD A;  4H80 A;  4I8Q A;  1UXT A;  2D4E A;  1A4Z A;  4ITB A;  4LH0 A;  2EIT A;  4WB9 A;  2H5G A;  4ZUK A;  4FR8 A;  3U4J A;  2WOX A;  4OHT A;  5EK6 A;  3V9G A;  5KLL A;  4C3S A;  3IWJ A;  1UXN A;  4OE6 A;  4I8P A;  3TY7 A;  4I3U A;  5A2D D;  2EII A;  4V3F A;  1UXU A;  2BHQ A;  3R64 A;  4I3W A;  4QF6 A;  4YWE A;  5J6B A;  1EZ0 A;  2ONP A;  4OU2 A;  4X0T A;  5L2O A;  1A4S A;  4H7N A;  4LIH A;  2ONM A;  5EYU A;  3JZ4 A;  2WME A;  1O02 A;  4QET A;  3RHP A;  4LH1 A;  4OGD A;  2VLE A;  4U3W A;  4DNG A;  3VZ3 A;  4I1W A;  4GNZ A;  5DRU A;  1WND A;  4H73 A;  1WNB A;  4ZVY A;  4OUB A;  5AC0 A;  3RHL A;  3EK1 A;  5DIB A;  1NZW A;  2O2P A;  5F2C A;  2BJK A;  3EFV A;  1EUH A;  3ETF A;  2ONO A;  4I25 A;  4IHI A;  4WP7 A;  4PXN A;  3V4C A;  3VZ0 A;  2XDR A;  5L2N A;  4OE2 A;  4WJ9 A;  2EHQ A;  3RHQ A;  2O2Q A;  5ABM A;  4V3F C;  1AG8 A;  1KY8 A;  4ITA A;  2Y5D A;  3MY7 A;  4K57 A;  3RHM A;  3RHJ A;  3V9I A;  4CAZ A;  3INJ A;  3I44 A;  4YWV A;  4IT9 A;  4GO4 A;  2WME C;  3V9K A;  3N81 A;  4GO2 A;  4KWG A;  4LH3 A;  3RH9 A;  4LEM A;  4GO0 A;  4F3X A;  4V37 A;  4OE5 A;  1T90 A;  4PZ2 A;  5J7I A;  4JBE A;  5L2M A;  5EZ4 A;  3K2W A;  4QJE B;  2J40 A;  4QTO A;  4QN2 A;  3ROS A;  3SZB A;  4E3X A;  5A2D A;  4OE4 A;  2ESD A;  5AC2 A;  4MPY A;  4PXL B;  5AC1 A;  2EHU A;  4ZUL A;  2ONN A;  1UXR A;  4I26 A;  4ZZ7 A;  4I3X A;  1O01 A;  4L2O A;  2QE0 A;  5FHZ A;  3RHR A;  3VZ2 A;  2W8P A;  4O5H A;  4GHK A;  4LGZ A;  4QJE A;  5EUY A;  1NZX A;  5KF0 A;  4IYM A;  4I2R A;  3V9H A;  4ZXU A;  1VLU A;  4KWF A;  1O20 A;  4IDM A;  4ZWL A;  2W8Q A; 
#chains in the Genus database with same CATH topology
 2HG2 A;  4I9B A;  4IDS A;  5EXF A;  2BHP A;  3ZQA A;  1EYY A;  3VZ1 A;  1BPW A;  1CW3 A;  2W8R A;  4LH2 A;  4Q92 A;  3V9J A;  4CBB A;  1O9J A;  2Y53 A;  4NU9 A;  2IY6 A;  4X2Q A;  1QI1 A;  3N83 A;  2J6L A;  2W8N A;  1UXV A;  4JDC A;  3INL A;  4JZ6 A;  4NS3 A;  2BJA A;  4O6R A;  5J78 A;  5A2D C;  3N82 A;  4NPI A;  4GO3 A;  3RJL A;  2EIW A;  5EKC A;  2O2R A;  5KLN A;  4A0M A;  4I3V A;  3QAN A;  3PRL A;  3SZA A;  5KJ5 A;  4QYJ A;  5KLO A;  3RHO A;  1BI9 A;  2ILU A;  3JU8 A;  5L13 A;  2ID2 A;  4I3T A;  1O04 A;  3PQA A;  5EEB A;  5JRY A;  2OPX A;  2Y52 A;  4PXL A;  3RHH A;  3R31 A;  1QI6 A;  3B4W A;  1O05 A;  1UXQ A;  4NMK A;  3SZ9 A;  5KLK A;  4QGK A;  4YWU A;  1UZB A;  1AD3 A;  2JG7 A;  3N80 A;  4X4L A;  4E4G A;  4MPB A;  2EJD A;  2W8O A;  4NEA A;  3K9D A;  3IWK A;  1NZZ A;  2Y51 A;  4L1O A;  2EUH A;  2IMP A;  4NMJ A;  2VRO A;  1O00 A;  1BXS A;  1ZUM A;  2EJ6 A;  4X0U A;  1UXP A;  4KNA A;  2J5N A;  3V9L A;  5KLM A;  4DAL A;  4ZVX A;  4ZVW A;  4FQF A;  4WPN A;  2EJL A;  5DBV A;  3RHD A;  4H80 A;  4I8Q A;  1UXT A;  2D4E A;  1A4Z A;  4ITB A;  4LH0 A;  2EIT A;  4WB9 A;  2H5G A;  4ZUK A;  4FR8 A;  3U4J A;  2WOX A;  4OHT A;  5EK6 A;  3V9G A;  5KLL A;  4C3S A;  3IWJ A;  1UXN A;  4OE6 A;  4I8P A;  3TY7 A;  4I3U A;  5A2D D;  2EII A;  4V3F A;  1UXU A;  2BHQ A;  3R64 A;  4I3W A;  4QF6 A;  4YWE A;  5J6B A;  1EZ0 A;  2ONP A;  4OU2 A;  4X0T A;  5L2O A;  1A4S A;  4H7N A;  4LIH A;  2ONM A;  5EYU A;  3JZ4 A;  2WME A;  1O02 A;  4QET A;  3RHP A;  4LH1 A;  4OGD A;  2VLE A;  4U3W A;  4DNG A;  3VZ3 A;  4I1W A;  4GNZ A;  5DRU A;  1WND A;  4H73 A;  1WNB A;  4ZVY A;  4OUB A;  5AC0 A;  3RHL A;  3EK1 A;  5DIB A;  1NZW A;  2O2P A;  5F2C A;  2BJK A;  3EFV A;  1EUH A;  3ETF A;  2ONO A;  4I25 A;  4IHI A;  4WP7 A;  4PXN A;  3V4C A;  3VZ0 A;  2XDR A;  5L2N A;  4OE2 A;  4WJ9 A;  2EHQ A;  3RHQ A;  2O2Q A;  5ABM A;  4V3F C;  1AG8 A;  1KY8 A;  4ITA A;  2Y5D A;  3MY7 A;  4K57 A;  3RHM A;  3RHJ A;  3V9I A;  4CAZ A;  3INJ A;  3I44 A;  4YWV A;  4IT9 A;  4GO4 A;  2WME C;  3V9K A;  3N81 A;  4GO2 A;  4KWG A;  4LH3 A;  3RH9 A;  4LEM A;  4GO0 A;  4F3X A;  4V37 A;  4OE5 A;  1T90 A;  4PZ2 A;  5J7I A;  4JBE A;  5L2M A;  5EZ4 A;  3K2W A;  4QJE B;  2J40 A;  4QTO A;  4QN2 A;  3ROS A;  3SZB A;  4E3X A;  5A2D A;  4OE4 A;  2ESD A;  5AC2 A;  4MPY A;  4PXL B;  5AC1 A;  2EHU A;  4ZUL A;  2ONN A;  1UXR A;  4I26 A;  4ZZ7 A;  4I3X A;  1O01 A;  4L2O A;  2QE0 A;  5FHZ A;  3RHR A;  3VZ2 A;  2W8P A;  4O5H A;  4GHK A;  4LGZ A;  4QJE A;  5EUY A;  1NZX A;  5KF0 A;  4IYM A;  4I2R A;  3V9H A;  4ZXU A;  1VLU A;  4KWF A;  1O20 A;  4IDM A;  4ZWL A;  2W8Q A; 
#chains in the Genus database with same CATH homology
 2HG2 A;  4I9B A;  4IDS A;  5EXF A;  2BHP A;  3ZQA A;  1EYY A;  3VZ1 A;  1BPW A;  1CW3 A;  2W8R A;  4LH2 A;  4Q92 A;  3V9J A;  4CBB A;  1O9J A;  2Y53 A;  4NU9 A;  2IY6 A;  4X2Q A;  1QI1 A;  3N83 A;  2J6L A;  2W8N A;  1UXV A;  4JDC A;  3INL A;  4JZ6 A;  4NS3 A;  2BJA A;  4O6R A;  5J78 A;  5A2D C;  3N82 A;  4NPI A;  4GO3 A;  3RJL A;  2EIW A;  5EKC A;  2O2R A;  5KLN A;  4A0M A;  4I3V A;  3QAN A;  3PRL A;  3SZA A;  5KJ5 A;  4QYJ A;  5KLO A;  3RHO A;  1BI9 A;  2ILU A;  3JU8 A;  5L13 A;  2ID2 A;  4I3T A;  1O04 A;  3PQA A;  5EEB A;  5JRY A;  2OPX A;  2Y52 A;  4PXL A;  3RHH A;  3R31 A;  1QI6 A;  3B4W A;  1O05 A;  1UXQ A;  4NMK A;  3SZ9 A;  5KLK A;  4QGK A;  4YWU A;  1UZB A;  1AD3 A;  2JG7 A;  3N80 A;  4X4L A;  4E4G A;  4MPB A;  2EJD A;  2W8O A;  4NEA A;  3K9D A;  3IWK A;  1NZZ A;  2Y51 A;  4L1O A;  2EUH A;  2IMP A;  4NMJ A;  2VRO A;  1O00 A;  1BXS A;  1ZUM A;  2EJ6 A;  4X0U A;  1UXP A;  4KNA A;  2J5N A;  3V9L A;  5KLM A;  4DAL A;  4ZVX A;  4ZVW A;  4FQF A;  4WPN A;  2EJL A;  5DBV A;  3RHD A;  4H80 A;  4I8Q A;  1UXT A;  2D4E A;  1A4Z A;  4ITB A;  4LH0 A;  2EIT A;  4WB9 A;  2H5G A;  4ZUK A;  4FR8 A;  3U4J A;  2WOX A;  4OHT A;  5EK6 A;  3V9G A;  5KLL A;  4C3S A;  3IWJ A;  1UXN A;  4OE6 A;  4I8P A;  3TY7 A;  4I3U A;  5A2D D;  2EII A;  4V3F A;  1UXU A;  2BHQ A;  3R64 A;  4I3W A;  4QF6 A;  4YWE A;  5J6B A;  1EZ0 A;  2ONP A;  4OU2 A;  4X0T A;  5L2O A;  1A4S A;  4H7N A;  4LIH A;  2ONM A;  5EYU A;  3JZ4 A;  2WME A;  1O02 A;  4QET A;  3RHP A;  4LH1 A;  4OGD A;  2VLE A;  4U3W A;  4DNG A;  3VZ3 A;  4I1W A;  4GNZ A;  5DRU A;  1WND A;  4H73 A;  1WNB A;  4ZVY A;  4OUB A;  5AC0 A;  3RHL A;  3EK1 A;  5DIB A;  1NZW A;  2O2P A;  5F2C A;  2BJK A;  3EFV A;  1EUH A;  3ETF A;  2ONO A;  4I25 A;  4IHI A;  4WP7 A;  4PXN A;  3V4C A;  3VZ0 A;  2XDR A;  5L2N A;  4OE2 A;  4WJ9 A;  2EHQ A;  3RHQ A;  2O2Q A;  5ABM A;  4V3F C;  1AG8 A;  1KY8 A;  4ITA A;  2Y5D A;  3MY7 A;  4K57 A;  3RHM A;  3RHJ A;  3V9I A;  4CAZ A;  3INJ A;  3I44 A;  4YWV A;  4IT9 A;  4GO4 A;  2WME C;  3V9K A;  3N81 A;  4GO2 A;  4KWG A;  4LH3 A;  3RH9 A;  4LEM A;  4GO0 A;  4F3X A;  4V37 A;  4OE5 A;  1T90 A;  4PZ2 A;  5J7I A;  4JBE A;  5L2M A;  5EZ4 A;  3K2W A;  4QJE B;  2J40 A;  4QTO A;  4QN2 A;  3ROS A;  3SZB A;  4E3X A;  5A2D A;  4OE4 A;  2ESD A;  5AC2 A;  4MPY A;  4PXL B;  5AC1 A;  2EHU A;  4ZUL A;  2ONN A;  1UXR A;  4I26 A;  4ZZ7 A;  4I3X A;  1O01 A;  4L2O A;  2QE0 A;  5FHZ A;  3RHR A;  3VZ2 A;  2W8P A;  4O5H A;  4GHK A;  4LGZ A;  4QJE A;  5EUY A;  1NZX A;  5KF0 A;  4IYM A;  4I2R A;  3V9H A;  4ZXU A;  1VLU A;  4KWF A;  1O20 A;  4IDM A;  4ZWL A;  2W8Q A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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