5I0AA

Reca mini intein in complex with cisplatin
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
142
structure length
142
Chain Sequence
CLAEGTRIFDPVTGTTHRIEDVVDGRKPIHVVAAAKDGTLHARPVVSWFDQGTRDVIGLRIAGGAILWATPDHKVLTEYGWRAAGELRKGDRVAVRDVETGELRYSVIREVLPTRRARTFDLEVEELHTLVAEGVVVHACSP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights into protein splicing inhibition by platinum therapeutics as potential anti-microbials
rcsb
molecule tags Splicing
source organism Mycobacterium tuberculosis
molecule keywords Intein
total genus 33
structure length 142
sequence length 142
ec nomenclature
pdb deposition date 2016-02-03
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.16.10 Mainly Beta Beta Complex Endonuclease - Pi-scei; Chain A, domain 1 Hedgehog/Intein (Hint) domain 5i0aA00
3NZMA 1DQ3A 2JNQA 4E2TA 4KL5A 1VDEA 2KEQA 5K08A 4KL6A 1AM2A 4GIGA 5I0AA 1LWSA 2CW7A 1DFAA 1UM2A 2JMZA 1GPPA 1JVAA 2L8LA 1ZDEA 2IN0A 2CW8A 2LQMA 3IGDA 1ZD7A 2LCJA 4OZ6A 2IN8A 2LWYA 4O1RA 4O1SA 2IMZA 2IN9A 1EF0A 1LWTA 3IFJA 1AT0A 4E2UA 1MI8A
chains in the Genus database with same CATH superfamily
3NZMA 1DQ3A 2JNQA 4LX3A 4E2TA 4KL5A 1VDEA 2KEQA 5K08A 4KL6A 1AM2A 4GIGA 5I0AA 4QFQA 1LWSA 2CW7A 1DFAA 1UM2A 2JMZA 1GPPA 1JVAA 2L8LA 1ZDEA 2IN0A 2CW8A 2LQMA 3IGDA 1ZD7A 2LCJA 4OZ6A 2IN8A 2LWYA 4O1RA 4O1SA 2IMZA 2IN9A 1EF0A 1LWTA 3IFJA 1AT0A 4E2UA 1MI8A
chains in the Genus database with same CATH topology
3NZMA 1DQ3A 2JNQA 4E2TA 4KL5A 1VDEA 2KEQA 5K08A 4KL6A 1AM2A 4GIGA 5I0AA 1LWSA 2CW7A 1DFAA 1UM2A 2JMZA 1GPPA 1JVAA 2L8LA 1ZDEA 2IN0A 2CW8A 2LQMA 3IGDA 1ZD7A 2LCJA 4OZ6A 2IN8A 2LWYA 4O1RA 4O1SA 2IMZA 2IN9A 1EF0A 1LWTA 3IFJA 1AT0A 4E2UA 1MI8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NZM A;  1DQ3 A;  2JNQ A;  4E2T A;  4KL5 A;  1VDE A;  2KEQ A;  5K08 A;  4KL6 A;  1AM2 A;  4GIG A;  5I0A A;  1LWS A;  2CW7 A;  1DFA A;  1UM2 A;  2JMZ A;  1GPP A;  1JVA A;  2L8L A;  1ZDE A;  2IN0 A;  2CW8 A;  2LQM A;  3IGD A;  1ZD7 A;  2LCJ A;  4OZ6 A;  2IN8 A;  2LWY A;  4O1R A;  4O1S A;  2IMZ A;  2IN9 A;  1EF0 A;  1LWT A;  3IFJ A;  1AT0 A;  4E2U A;  1MI8 A; 
#chains in the Genus database with same CATH topology
 3NZM A;  1DQ3 A;  2JNQ A;  4LX3 A;  4E2T A;  4KL5 A;  1VDE A;  2KEQ A;  5K08 A;  4KL6 A;  1AM2 A;  4GIG A;  5I0A A;  4QFQ A;  1LWS A;  2CW7 A;  1DFA A;  1UM2 A;  2JMZ A;  1GPP A;  1JVA A;  2L8L A;  1ZDE A;  2IN0 A;  2CW8 A;  2LQM A;  3IGD A;  1ZD7 A;  2LCJ A;  4OZ6 A;  2IN8 A;  2LWY A;  4O1R A;  4O1S A;  2IMZ A;  2IN9 A;  1EF0 A;  1LWT A;  3IFJ A;  1AT0 A;  4E2U A;  1MI8 A; 
#chains in the Genus database with same CATH homology
 3NZM A;  1DQ3 A;  2JNQ A;  4E2T A;  4KL5 A;  1VDE A;  2KEQ A;  5K08 A;  4KL6 A;  1AM2 A;  4GIG A;  5I0A A;  1LWS A;  2CW7 A;  1DFA A;  1UM2 A;  2JMZ A;  1GPP A;  1JVA A;  2L8L A;  1ZDE A;  2IN0 A;  2CW8 A;  2LQM A;  3IGD A;  1ZD7 A;  2LCJ A;  4OZ6 A;  2IN8 A;  2LWY A;  4O1R A;  4O1S A;  2IMZ A;  2IN9 A;  1EF0 A;  1LWT A;  3IFJ A;  1AT0 A;  4E2U A;  1MI8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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