5IRCA

P190a gap domain complex with rhoa
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
201
structure length
200
Chain Sequence
AGSWESNYFGVPLTTVVTPEKPIPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQDHNLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYSMQIDLVEAHKINDREQKLHALKEVLKKFPKENHEVFKYVISHLNRVSHNNKVNLMTSENLSICFWPTLMRPDFSSMDALTATRSYQTIIELFIQQPFFFYNR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Deciphering the Molecular and Functional Basis of RHOGAP Family Proteins: A SYSTEMATIC APPROACH TOWARD SELECTIVE INACTIVATION OF RHO FAMILY PROTEINS.
pubmed doi rcsb
molecule tags Protein binding
source organism Rattus norvegicus
molecule keywords Rho GTPase-activating protein 35
total genus 75
structure length 200
sequence length 201
chains with identical sequence B
ec nomenclature
pdb deposition date 2016-03-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 5ircA00
2XS6A 2MBGA 3WPQA 3W6RA 5C2JA 5C5SA 3FK2A 1GRNB 1OW3A 1F7CA 5JD0A 2EE4A 1TX4A 2OSAA 3EAPA 3CXLA 1XA6A 3MSXB 2QV2A 3WPSA 5JCPA 1PBWA 3QISA 1RGPA 1AM4A 3BYIA 5HPYA 2NGRB 5IRCA 3IUGA 3KUQA 2EE5A 2OVJA
chains in the Genus database with same CATH superfamily
2XS6A 2MBGA 3WPQA 3W6RA 5C2JA 5C5SA 3FK2A 1GRNB 1OW3A 1F7CA 5JD0A 2EE4A 1TX4A 2OSAA 3EAPA 3CXLA 1XA6A 3MSXB 2QV2A 3WPSA 5JCPA 1PBWA 3QISA 1RGPA 1AM4A 3BYIA 5HPYA 2NGRB 5IRCA 3IUGA 3KUQA 2EE5A 2OVJA
chains in the Genus database with same CATH topology
2XS6A 2MBGA 3WPQA 3W6RA 5C2JA 5C5SA 3FK2A 1GRNB 1OW3A 1F7CA 5JD0A 2EE4A 1TX4A 2OSAA 3EAPA 3CXLA 1XA6A 3MSXB 2QV2A 3WPSA 5JCPA 1PBWA 3QISA 1RGPA 1AM4A 3BYIA 5HPYA 2NGRB 5IRCA 3IUGA 3KUQA 2EE5A 2OVJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XS6 A;  2MBG A;  3WPQ A;  3W6R A;  5C2J A;  5C5S A;  3FK2 A;  1GRN B;  1OW3 A;  1F7C A;  5JD0 A;  2EE4 A;  1TX4 A;  2OSA A;  3EAP A;  3CXL A;  1XA6 A;  3MSX B;  2QV2 A;  3WPS A;  5JCP A;  1PBW A;  3QIS A;  1RGP A;  1AM4 A;  3BYI A;  5HPY A;  2NGR B;  5IRC A;  3IUG A;  3KUQ A;  2EE5 A;  2OVJ A; 
#chains in the Genus database with same CATH topology
 2XS6 A;  2MBG A;  3WPQ A;  3W6R A;  5C2J A;  5C5S A;  3FK2 A;  1GRN B;  1OW3 A;  1F7C A;  5JD0 A;  2EE4 A;  1TX4 A;  2OSA A;  3EAP A;  3CXL A;  1XA6 A;  3MSX B;  2QV2 A;  3WPS A;  5JCP A;  1PBW A;  3QIS A;  1RGP A;  1AM4 A;  3BYI A;  5HPY A;  2NGR B;  5IRC A;  3IUG A;  3KUQ A;  2EE5 A;  2OVJ A; 
#chains in the Genus database with same CATH homology
 2XS6 A;  2MBG A;  3WPQ A;  3W6R A;  5C2J A;  5C5S A;  3FK2 A;  1GRN B;  1OW3 A;  1F7C A;  5JD0 A;  2EE4 A;  1TX4 A;  2OSA A;  3EAP A;  3CXL A;  1XA6 A;  3MSX B;  2QV2 A;  3WPS A;  5JCP A;  1PBW A;  3QIS A;  1RGP A;  1AM4 A;  3BYI A;  5HPY A;  2NGR B;  5IRC A;  3IUG A;  3KUQ A;  2EE5 A;  2OVJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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