1GZYB

Human insulin-like growth factor; in-house data
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
64
structure length
57
Chain Sequence
ETLCGAELVDALQFVCGDRGFYFNKPTGYPQTGIVDECCFRSCDLRRLEMYCAPLKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Growth factor
molecule keywords INSULIN-LIKE GROWTH FACTOR I
publication title Structural Origins of the Functional Divergence of Human Insulin-Like Growth Factor-I and Insulin
pubmed doi rcsb
source organism Homo sapiens
total genus 15
structure length 57
sequence length 64
ec nomenclature
pdb deposition date 2002-06-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 1gzyB00
2KQPA 2LWZA 5L3NA 1IMXA 2KJIA 2DSPI 2GF1A 1IGLA 1WQJI 1H59A 1EFEA 2L29B 1GZRB 1TGRA 2DSRI 3KR3D 3LRIA 6INSE 1GZYB 5L3MA 1PMXA 2DSQC 1SJUA 1B9GA 1GZZB 1ZEIA 5L3LA 4XSSB 1BQTA 2JZQA 3GF1A 1H02B
chains in the Genus database with same CATH superfamily
2KQPA 2LWZA 5L3NA 1IMXA 2KJIA 3F2CA 2L14B 2DSPI 2GF1A 1IGLA 1WQJI 1H59A 1EFEA 2L29B 3F2DA 1GZRB 1TGRA 2DSRI 3KR3D 3LRIA 6INSE 1GZYB 5L3MA 1PMXA 3F2BA 2DSQC 1SJUA 1B9GA 1GZZB 1ZEIA 5L3LA 4XSSB 1BQTA 2JZQA 3GF1A 1H02B
chains in the Genus database with same CATH topology
2KQPA 2LWZA 5L3NA 1IMXA 2KJIA 2DSPI 2GF1A 1IGLA 1WQJI 1H59A 1EFEA 2L29B 1GZRB 1TGRA 2DSRI 3KR3D 3LRIA 6INSE 1GZYB 5L3MA 1PMXA 2DSQC 1SJUA 1B9GA 1GZZB 1ZEIA 5L3LA 4XSSB 1BQTA 2JZQA 3GF1A 1H02B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KQP A;  2LWZ A;  5L3N A;  1IMX A;  2KJI A;  2DSP I;  2GF1 A;  1IGL A;  1WQJ I;  1H59 A;  1EFE A;  2L29 B;  1GZR B;  1TGR A;  2DSR I;  3KR3 D;  3LRI A;  6INS E;  1GZY B;  5L3M A;  1PMX A;  2DSQ C;  1SJU A;  1B9G A;  1GZZ B;  1ZEI A;  5L3L A;  4XSS B;  1BQT A;  2JZQ A;  3GF1 A;  1H02 B; 
#chains in the Genus database with same CATH topology
 2KQP A;  2LWZ A;  5L3N A;  1IMX A;  2KJI A;  3F2C A;  2L14 B;  2DSP I;  2GF1 A;  1IGL A;  1WQJ I;  1H59 A;  1EFE A;  2L29 B;  3F2D A;  1GZR B;  1TGR A;  2DSR I;  3KR3 D;  3LRI A;  6INS E;  1GZY B;  5L3M A;  1PMX A;  3F2B A;  2DSQ C;  1SJU A;  1B9G A;  1GZZ B;  1ZEI A;  5L3L A;  4XSS B;  1BQT A;  2JZQ A;  3GF1 A;  1H02 B; 
#chains in the Genus database with same CATH homology
 2KQP A;  2LWZ A;  5L3N A;  1IMX A;  2KJI A;  2DSP I;  2GF1 A;  1IGL A;  1WQJ I;  1H59 A;  1EFE A;  2L29 B;  1GZR B;  1TGR A;  2DSR I;  3KR3 D;  3LRI A;  6INS E;  1GZY B;  5L3M A;  1PMX A;  2DSQ C;  1SJU A;  1B9G A;  1GZZ B;  1ZEI A;  5L3L A;  4XSS B;  1BQT A;  2JZQ A;  3GF1 A;  1H02 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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