1IMXA

1.8 angstrom crystal structure of igf-1
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
62
structure length
56
Chain Sequence
ETLCGAELVDALQFVCGDRGFYFNKPTGYGSSTGIVDECCFRSCDLRRLEMYCAPL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hormone/growth factor
molecule keywords Insulin-like Growth Factor 1A
publication title Crystal structure of human insulin-like growth factor-1: detergent binding inhibits binding protein interactions.
pubmed doi rcsb
source organism Homo sapiens
total genus 16
structure length 56
sequence length 62
ec nomenclature
pdb deposition date 2001-05-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 1imxA00
1TGRA 1EFEA 2L29B 1IGLA 2JZQA 3KR3D 2KQPA 1GZZB 1H59A 1ZEIA 1H02B 2DSPI 3GF1A 2GF1A 5L3LA 1GZYB 1SJUA 2DSRI 1BQTA 2LWZA 2DSQC 5L3MA 3LRIA 6INSE 1WQJI 1IMXA 1GZRB 4XSSB 5L3NA 2KJIA 1B9GA 1PMXA
chains in the Genus database with same CATH superfamily
1TGRA 1EFEA 2L29B 1IGLA 2JZQA 3KR3D 2KQPA 1GZZB 1H59A 3F2DA 3F2CA 1ZEIA 1H02B 2L14B 2DSPI 3GF1A 2GF1A 5L3LA 1GZYB 1SJUA 2DSRI 1BQTA 2LWZA 2DSQC 5L3MA 3LRIA 6INSE 1WQJI 1IMXA 1GZRB 4XSSB 5L3NA 2KJIA 1B9GA 3F2BA 1PMXA
chains in the Genus database with same CATH topology
1TGRA 1EFEA 2L29B 1IGLA 2JZQA 3KR3D 2KQPA 1GZZB 1H59A 1ZEIA 1H02B 2DSPI 3GF1A 2GF1A 5L3LA 1GZYB 1SJUA 2DSRI 1BQTA 2LWZA 2DSQC 5L3MA 3LRIA 6INSE 1WQJI 1IMXA 1GZRB 4XSSB 5L3NA 2KJIA 1B9GA 1PMXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TGR A;  1EFE A;  2L29 B;  1IGL A;  2JZQ A;  3KR3 D;  2KQP A;  1GZZ B;  1H59 A;  1ZEI A;  1H02 B;  2DSP I;  3GF1 A;  2GF1 A;  5L3L A;  1GZY B;  1SJU A;  2DSR I;  1BQT A;  2LWZ A;  2DSQ C;  5L3M A;  3LRI A;  6INS E;  1WQJ I;  1IMX A;  1GZR B;  4XSS B;  5L3N A;  2KJI A;  1B9G A;  1PMX A; 
#chains in the Genus database with same CATH topology
 1TGR A;  1EFE A;  2L29 B;  1IGL A;  2JZQ A;  3KR3 D;  2KQP A;  1GZZ B;  1H59 A;  3F2D A;  3F2C A;  1ZEI A;  1H02 B;  2L14 B;  2DSP I;  3GF1 A;  2GF1 A;  5L3L A;  1GZY B;  1SJU A;  2DSR I;  1BQT A;  2LWZ A;  2DSQ C;  5L3M A;  3LRI A;  6INS E;  1WQJ I;  1IMX A;  1GZR B;  4XSS B;  5L3N A;  2KJI A;  1B9G A;  3F2B A;  1PMX A; 
#chains in the Genus database with same CATH homology
 1TGR A;  1EFE A;  2L29 B;  1IGL A;  2JZQ A;  3KR3 D;  2KQP A;  1GZZ B;  1H59 A;  1ZEI A;  1H02 B;  2DSP I;  3GF1 A;  2GF1 A;  5L3L A;  1GZY B;  1SJU A;  2DSR I;  1BQT A;  2LWZ A;  2DSQ C;  5L3M A;  3LRI A;  6INS E;  1WQJ I;  1IMX A;  1GZR B;  4XSS B;  5L3N A;  2KJI A;  1B9G A;  1PMX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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