5L3NA

D11 bound [n29, s39_pq]-igf-ii
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
69
structure length
69
Chain Sequence
AYRPSETLCGGELVDTLQFVCGDRGFYFNRPASRVSRRSPQRGIVEECCFRSCDLALLETYCATPAKSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cell cycle
molecule keywords Insulin-like growth factor II
publication title Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain.
pubmed doi rcsb
source organism Homo sapiens
total genus 12
structure length 69
sequence length 69
ec nomenclature
pdb deposition date 2016-05-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 5l3nA00
2KJIA 2LWZA 1H59A 1ZEIA 4XSSB 6INSE 1BQTA 1IGLA 3LRIA 1H02B 1EFEA 3GF1A 2KQPA 1TGRA 3KR3D 1GZYB 2GF1A 2JZQA 1IMXA 2L29B 5L3NA 1GZZB 2DSQC 2DSPI 1SJUA 1GZRB 1PMXA 1WQJI 5L3LA 2DSRI 5L3MA 1B9GA
chains in the Genus database with same CATH superfamily
2KJIA 2LWZA 1H59A 1ZEIA 3F2DA 4XSSB 6INSE 1BQTA 1IGLA 3LRIA 1H02B 1EFEA 3GF1A 2KQPA 1TGRA 3KR3D 1GZYB 2GF1A 2JZQA 1IMXA 2L29B 5L3NA 1GZZB 3F2CA 2DSQC 3F2BA 2DSPI 1SJUA 1GZRB 1PMXA 1WQJI 5L3LA 2L14B 2DSRI 5L3MA 1B9GA
chains in the Genus database with same CATH topology
2KJIA 2LWZA 1H59A 1ZEIA 4XSSB 6INSE 1BQTA 1IGLA 3LRIA 1H02B 1EFEA 3GF1A 2KQPA 1TGRA 3KR3D 1GZYB 2GF1A 2JZQA 1IMXA 2L29B 5L3NA 1GZZB 2DSQC 2DSPI 1SJUA 1GZRB 1PMXA 1WQJI 5L3LA 2DSRI 5L3MA 1B9GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KJI A;  2LWZ A;  1H59 A;  1ZEI A;  4XSS B;  6INS E;  1BQT A;  1IGL A;  3LRI A;  1H02 B;  1EFE A;  3GF1 A;  2KQP A;  1TGR A;  3KR3 D;  1GZY B;  2GF1 A;  2JZQ A;  1IMX A;  2L29 B;  5L3N A;  1GZZ B;  2DSQ C;  2DSP I;  1SJU A;  1GZR B;  1PMX A;  1WQJ I;  5L3L A;  2DSR I;  5L3M A;  1B9G A; 
#chains in the Genus database with same CATH topology
 2KJI A;  2LWZ A;  1H59 A;  1ZEI A;  3F2D A;  4XSS B;  6INS E;  1BQT A;  1IGL A;  3LRI A;  1H02 B;  1EFE A;  3GF1 A;  2KQP A;  1TGR A;  3KR3 D;  1GZY B;  2GF1 A;  2JZQ A;  1IMX A;  2L29 B;  5L3N A;  1GZZ B;  3F2C A;  2DSQ C;  3F2B A;  2DSP I;  1SJU A;  1GZR B;  1PMX A;  1WQJ I;  5L3L A;  2L14 B;  2DSR I;  5L3M A;  1B9G A; 
#chains in the Genus database with same CATH homology
 2KJI A;  2LWZ A;  1H59 A;  1ZEI A;  4XSS B;  6INS E;  1BQT A;  1IGL A;  3LRI A;  1H02 B;  1EFE A;  3GF1 A;  2KQP A;  1TGR A;  3KR3 D;  1GZY B;  2GF1 A;  2JZQ A;  1IMX A;  2L29 B;  5L3N A;  1GZZ B;  2DSQ C;  2DSP I;  1SJU A;  1GZR B;  1PMX A;  1WQJ I;  5L3L A;  2DSR I;  5L3M A;  1B9G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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