5L3LA

D11 bound igf-ii
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
67
structure length
67
Chain Sequence
AYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSRGIVEECCFRSCDLALLETYCATPAKSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cell cycle
molecule keywords Insulin-like growth factor II
publication title Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain.
pubmed doi rcsb
source organism Homo sapiens
total genus 10
structure length 67
sequence length 67
ec nomenclature
pdb deposition date 2016-05-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 5l3lA00
2GF1A 3LRIA 2DSQC 2DSPI 1PMXA 2L29B 1H59A 3KR3D 2KJIA 2KQPA 3GF1A 4XSSB 1ZEIA 5L3NA 1WQJI 1BQTA 1SJUA 1GZZB 1TGRA 2JZQA 5L3LA 1IMXA 1B9GA 2DSRI 1GZYB 1EFEA 5L3MA 1H02B 6INSE 1GZRB 1IGLA 2LWZA
chains in the Genus database with same CATH superfamily
2GF1A 3LRIA 2DSQC 2DSPI 1PMXA 2L29B 1H59A 3KR3D 2KJIA 2KQPA 3F2BA 3GF1A 4XSSB 1ZEIA 5L3NA 1WQJI 1BQTA 1SJUA 1GZZB 1TGRA 2JZQA 2L14B 5L3LA 1IMXA 1B9GA 2DSRI 1GZYB 1EFEA 5L3MA 1H02B 6INSE 3F2DA 1GZRB 1IGLA 2LWZA 3F2CA
chains in the Genus database with same CATH topology
2GF1A 3LRIA 2DSQC 2DSPI 1PMXA 2L29B 1H59A 3KR3D 2KJIA 2KQPA 3GF1A 4XSSB 1ZEIA 5L3NA 1WQJI 1BQTA 1SJUA 1GZZB 1TGRA 2JZQA 5L3LA 1IMXA 1B9GA 2DSRI 1GZYB 1EFEA 5L3MA 1H02B 6INSE 1GZRB 1IGLA 2LWZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GF1 A;  3LRI A;  2DSQ C;  2DSP I;  1PMX A;  2L29 B;  1H59 A;  3KR3 D;  2KJI A;  2KQP A;  3GF1 A;  4XSS B;  1ZEI A;  5L3N A;  1WQJ I;  1BQT A;  1SJU A;  1GZZ B;  1TGR A;  2JZQ A;  5L3L A;  1IMX A;  1B9G A;  2DSR I;  1GZY B;  1EFE A;  5L3M A;  1H02 B;  6INS E;  1GZR B;  1IGL A;  2LWZ A; 
#chains in the Genus database with same CATH topology
 2GF1 A;  3LRI A;  2DSQ C;  2DSP I;  1PMX A;  2L29 B;  1H59 A;  3KR3 D;  2KJI A;  2KQP A;  3F2B A;  3GF1 A;  4XSS B;  1ZEI A;  5L3N A;  1WQJ I;  1BQT A;  1SJU A;  1GZZ B;  1TGR A;  2JZQ A;  2L14 B;  5L3L A;  1IMX A;  1B9G A;  2DSR I;  1GZY B;  1EFE A;  5L3M A;  1H02 B;  6INS E;  3F2D A;  1GZR B;  1IGL A;  2LWZ A;  3F2C A; 
#chains in the Genus database with same CATH homology
 2GF1 A;  3LRI A;  2DSQ C;  2DSP I;  1PMX A;  2L29 B;  1H59 A;  3KR3 D;  2KJI A;  2KQP A;  3GF1 A;  4XSS B;  1ZEI A;  5L3N A;  1WQJ I;  1BQT A;  1SJU A;  1GZZ B;  1TGR A;  2JZQ A;  5L3L A;  1IMX A;  1B9G A;  2DSR I;  1GZY B;  1EFE A;  5L3M A;  1H02 B;  6INS E;  1GZR B;  1IGL A;  2LWZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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