1H02B

Human insulin-like growth factor; srs daresbury data
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
66
structure length
64
Chain Sequence
ETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSAPQTGIVDECCFRSCDLRRLEMYCAPLKPAK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cell adhesion
molecule keywords INSULIN-LIKE GROWTH FACTOR I
publication title Structural Origins of the Functional Divergence of Human Insulin-Like Growth Factor-I and Insulin
pubmed doi rcsb
source organism Homo sapiens
total genus 12
structure length 64
sequence length 66
ec nomenclature
pdb deposition date 2002-06-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 1h02B00
2GF1A 2LWZA 3KR3D 6INSE 1GZRB 4XSSB 1BQTA 1PMXA 1TGRA 1EFEA 1H02B 2JZQA 1IGLA 1GZYB 2KJIA 1H59A 3LRIA 1WQJI 5L3LA 2DSQC 1IMXA 5L3MA 2DSRI 2KQPA 3GF1A 1B9GA 5L3NA 1GZZB 1ZEIA 2DSPI 1SJUA 2L29B
chains in the Genus database with same CATH superfamily
2GF1A 2LWZA 3KR3D 6INSE 1GZRB 4XSSB 1BQTA 1PMXA 3F2DA 1TGRA 3F2BA 1EFEA 1H02B 2JZQA 1IGLA 1GZYB 2L14B 2KJIA 1H59A 3LRIA 1WQJI 3F2CA 5L3LA 2DSQC 1IMXA 5L3MA 2DSRI 2KQPA 3GF1A 1B9GA 5L3NA 1GZZB 1ZEIA 2DSPI 1SJUA 2L29B
chains in the Genus database with same CATH topology
2GF1A 2LWZA 3KR3D 6INSE 1GZRB 4XSSB 1BQTA 1PMXA 1TGRA 1EFEA 1H02B 2JZQA 1IGLA 1GZYB 2KJIA 1H59A 3LRIA 1WQJI 5L3LA 2DSQC 1IMXA 5L3MA 2DSRI 2KQPA 3GF1A 1B9GA 5L3NA 1GZZB 1ZEIA 2DSPI 1SJUA 2L29B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GF1 A;  2LWZ A;  3KR3 D;  6INS E;  1GZR B;  4XSS B;  1BQT A;  1PMX A;  1TGR A;  1EFE A;  1H02 B;  2JZQ A;  1IGL A;  1GZY B;  2KJI A;  1H59 A;  3LRI A;  1WQJ I;  5L3L A;  2DSQ C;  1IMX A;  5L3M A;  2DSR I;  2KQP A;  3GF1 A;  1B9G A;  5L3N A;  1GZZ B;  1ZEI A;  2DSP I;  1SJU A;  2L29 B; 
#chains in the Genus database with same CATH topology
 2GF1 A;  2LWZ A;  3KR3 D;  6INS E;  1GZR B;  4XSS B;  1BQT A;  1PMX A;  3F2D A;  1TGR A;  3F2B A;  1EFE A;  1H02 B;  2JZQ A;  1IGL A;  1GZY B;  2L14 B;  2KJI A;  1H59 A;  3LRI A;  1WQJ I;  3F2C A;  5L3L A;  2DSQ C;  1IMX A;  5L3M A;  2DSR I;  2KQP A;  3GF1 A;  1B9G A;  5L3N A;  1GZZ B;  1ZEI A;  2DSP I;  1SJU A;  2L29 B; 
#chains in the Genus database with same CATH homology
 2GF1 A;  2LWZ A;  3KR3 D;  6INS E;  1GZR B;  4XSS B;  1BQT A;  1PMX A;  1TGR A;  1EFE A;  1H02 B;  2JZQ A;  1IGL A;  1GZY B;  2KJI A;  1H59 A;  3LRI A;  1WQJ I;  5L3L A;  2DSQ C;  1IMX A;  5L3M A;  2DSR I;  2KQP A;  3GF1 A;  1B9G A;  5L3N A;  1GZZ B;  1ZEI A;  2DSP I;  1SJU A;  2L29 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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