5L3MA

D11 bound [s39_pq]-igf-ii
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
69
structure length
69
Chain Sequence
AYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSPQRGIVEECCFRSCDLALLETYCATPAKSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cell cycle
molecule keywords Insulin-like growth factor II
publication title Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain.
pubmed doi rcsb
source organism Homo sapiens
total genus 18
structure length 69
sequence length 69
ec nomenclature
pdb deposition date 2016-05-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 5l3mA00
1WQJI 2DSRI 1BQTA 1GZRB 2LWZA 1IMXA 1TGRA 1B9GA 5L3NA 2DSQC 1EFEA 1H59A 2GF1A 5L3MA 1SJUA 5L3LA 2L29B 1GZZB 2JZQA 1IGLA 3GF1A 2KQPA 6INSE 1H02B 1GZYB 2KJIA 3KR3D 3LRIA 2DSPI 4XSSB 1ZEIA 1PMXA
chains in the Genus database with same CATH superfamily
1WQJI 2DSRI 1BQTA 1GZRB 2LWZA 1IMXA 1TGRA 3F2DA 1B9GA 5L3NA 2DSQC 1EFEA 1H59A 2GF1A 5L3MA 1SJUA 5L3LA 2L29B 1GZZB 2JZQA 1IGLA 3GF1A 2KQPA 3F2CA 3F2BA 6INSE 1H02B 1GZYB 2KJIA 3KR3D 3LRIA 2L14B 2DSPI 4XSSB 1ZEIA 1PMXA
chains in the Genus database with same CATH topology
1WQJI 2DSRI 1BQTA 1GZRB 2LWZA 1IMXA 1TGRA 1B9GA 5L3NA 2DSQC 1EFEA 1H59A 2GF1A 5L3MA 1SJUA 5L3LA 2L29B 1GZZB 2JZQA 1IGLA 3GF1A 2KQPA 6INSE 1H02B 1GZYB 2KJIA 3KR3D 3LRIA 2DSPI 4XSSB 1ZEIA 1PMXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WQJ I;  2DSR I;  1BQT A;  1GZR B;  2LWZ A;  1IMX A;  1TGR A;  1B9G A;  5L3N A;  2DSQ C;  1EFE A;  1H59 A;  2GF1 A;  5L3M A;  1SJU A;  5L3L A;  2L29 B;  1GZZ B;  2JZQ A;  1IGL A;  3GF1 A;  2KQP A;  6INS E;  1H02 B;  1GZY B;  2KJI A;  3KR3 D;  3LRI A;  2DSP I;  4XSS B;  1ZEI A;  1PMX A; 
#chains in the Genus database with same CATH topology
 1WQJ I;  2DSR I;  1BQT A;  1GZR B;  2LWZ A;  1IMX A;  1TGR A;  3F2D A;  1B9G A;  5L3N A;  2DSQ C;  1EFE A;  1H59 A;  2GF1 A;  5L3M A;  1SJU A;  5L3L A;  2L29 B;  1GZZ B;  2JZQ A;  1IGL A;  3GF1 A;  2KQP A;  3F2C A;  3F2B A;  6INS E;  1H02 B;  1GZY B;  2KJI A;  3KR3 D;  3LRI A;  2L14 B;  2DSP I;  4XSS B;  1ZEI A;  1PMX A; 
#chains in the Genus database with same CATH homology
 1WQJ I;  2DSR I;  1BQT A;  1GZR B;  2LWZ A;  1IMX A;  1TGR A;  1B9G A;  5L3N A;  2DSQ C;  1EFE A;  1H59 A;  2GF1 A;  5L3M A;  1SJU A;  5L3L A;  2L29 B;  1GZZ B;  2JZQ A;  1IGL A;  3GF1 A;  2KQP A;  6INS E;  1H02 B;  1GZY B;  2KJI A;  3KR3 D;  3LRI A;  2DSP I;  4XSS B;  1ZEI A;  1PMX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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