1TGRA

Crystal structure of mini-igf-1(2)
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
52
structure length
52
Chain Sequence
GPETLCGAELVDALQFVCGDRGFYFNKPKAKGIVDECCFRSCDLRRLEMYCA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hormone/growth factor
molecule keywords Insulin-like growth factor IA
publication title 1.42A crystal structure of mini-IGF-1(2): an analysis of the disulfide isomerization property and receptor binding property of IGF-1 based on the three-dimensional structure
pubmed doi rcsb
source organism Homo sapiens
total genus 16
structure length 52
sequence length 52
chains with identical sequence B
ec nomenclature
pdb deposition date 2004-05-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 1tgrA00
2DSPI 2JZQA 1GZRB 2KJIA 1BQTA 1H02B 2L29B 1TGRA 1WQJI 5L3LA 1SJUA 4XSSB 1PMXA 2GF1A 2DSQC 2LWZA 2KQPA 3GF1A 1EFEA 1IGLA 1IMXA 1ZEIA 1H59A 3LRIA 3KR3D 5L3NA 2DSRI 6INSE 1GZZB 5L3MA 1GZYB 1B9GA
chains in the Genus database with same CATH superfamily
2DSPI 2JZQA 1GZRB 3F2DA 2KJIA 1BQTA 1H02B 2L29B 1TGRA 1WQJI 5L3LA 1SJUA 4XSSB 1PMXA 2GF1A 2DSQC 2LWZA 2KQPA 3GF1A 3F2BA 1EFEA 1IGLA 2L14B 1IMXA 1ZEIA 1H59A 3LRIA 3KR3D 5L3NA 2DSRI 6INSE 3F2CA 1GZZB 5L3MA 1GZYB 1B9GA
chains in the Genus database with same CATH topology
2DSPI 2JZQA 1GZRB 2KJIA 1BQTA 1H02B 2L29B 1TGRA 1WQJI 5L3LA 1SJUA 4XSSB 1PMXA 2GF1A 2DSQC 2LWZA 2KQPA 3GF1A 1EFEA 1IGLA 1IMXA 1ZEIA 1H59A 3LRIA 3KR3D 5L3NA 2DSRI 6INSE 1GZZB 5L3MA 1GZYB 1B9GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DSP I;  2JZQ A;  1GZR B;  2KJI A;  1BQT A;  1H02 B;  2L29 B;  1TGR A;  1WQJ I;  5L3L A;  1SJU A;  4XSS B;  1PMX A;  2GF1 A;  2DSQ C;  2LWZ A;  2KQP A;  3GF1 A;  1EFE A;  1IGL A;  1IMX A;  1ZEI A;  1H59 A;  3LRI A;  3KR3 D;  5L3N A;  2DSR I;  6INS E;  1GZZ B;  5L3M A;  1GZY B;  1B9G A; 
#chains in the Genus database with same CATH topology
 2DSP I;  2JZQ A;  1GZR B;  3F2D A;  2KJI A;  1BQT A;  1H02 B;  2L29 B;  1TGR A;  1WQJ I;  5L3L A;  1SJU A;  4XSS B;  1PMX A;  2GF1 A;  2DSQ C;  2LWZ A;  2KQP A;  3GF1 A;  3F2B A;  1EFE A;  1IGL A;  2L14 B;  1IMX A;  1ZEI A;  1H59 A;  3LRI A;  3KR3 D;  5L3N A;  2DSR I;  6INS E;  3F2C A;  1GZZ B;  5L3M A;  1GZY B;  1B9G A; 
#chains in the Genus database with same CATH homology
 2DSP I;  2JZQ A;  1GZR B;  2KJI A;  1BQT A;  1H02 B;  2L29 B;  1TGR A;  1WQJ I;  5L3L A;  1SJU A;  4XSS B;  1PMX A;  2GF1 A;  2DSQ C;  2LWZ A;  2KQP A;  3GF1 A;  1EFE A;  1IGL A;  1IMX A;  1ZEI A;  1H59 A;  3LRI A;  3KR3 D;  5L3N A;  2DSR I;  6INS E;  1GZZ B;  5L3M A;  1GZY B;  1B9G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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