2GF1A

Solution structure of human insulin-like growth factor 1: a nuclear magnetic resonance and restrained molecular dynamics study
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
70
structure length
70
Chain Sequence
GPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Growth factor
molecule keywords INSULIN-LIKE GROWTH FACTOR I
publication title Solution structure of human insulin-like growth factor 1: a nuclear magnetic resonance and restrained molecular dynamics study.
pubmed doi rcsb
source organism Homo sapiens
total genus 24
structure length 70
sequence length 70
ec nomenclature
pdb deposition date 1991-01-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 2gf1A00
2DSPI 6INSE 3LRIA 1IMXA 1IGLA 1ZEIA 2L29B 2GF1A 1H59A 5L3NA 4XSSB 5L3MA 1TGRA 1GZYB 1H02B 3KR3D 1EFEA 2JZQA 1PMXA 2KQPA 2LWZA 1B9GA 1GZRB 2DSRI 1SJUA 3GF1A 2KJIA 1BQTA 5L3LA 2DSQC 1WQJI 1GZZB
chains in the Genus database with same CATH superfamily
2DSPI 6INSE 3LRIA 1IMXA 1IGLA 3F2BA 1ZEIA 2L29B 2GF1A 1H59A 5L3NA 4XSSB 5L3MA 1TGRA 2L14B 1GZYB 1H02B 3F2CA 3KR3D 3F2DA 1EFEA 2JZQA 1PMXA 2KQPA 2LWZA 1B9GA 1GZRB 2DSRI 1SJUA 3GF1A 2KJIA 1BQTA 5L3LA 2DSQC 1WQJI 1GZZB
chains in the Genus database with same CATH topology
2DSPI 6INSE 3LRIA 1IMXA 1IGLA 1ZEIA 2L29B 2GF1A 1H59A 5L3NA 4XSSB 5L3MA 1TGRA 1GZYB 1H02B 3KR3D 1EFEA 2JZQA 1PMXA 2KQPA 2LWZA 1B9GA 1GZRB 2DSRI 1SJUA 3GF1A 2KJIA 1BQTA 5L3LA 2DSQC 1WQJI 1GZZB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DSP I;  6INS E;  3LRI A;  1IMX A;  1IGL A;  1ZEI A;  2L29 B;  2GF1 A;  1H59 A;  5L3N A;  4XSS B;  5L3M A;  1TGR A;  1GZY B;  1H02 B;  3KR3 D;  1EFE A;  2JZQ A;  1PMX A;  2KQP A;  2LWZ A;  1B9G A;  1GZR B;  2DSR I;  1SJU A;  3GF1 A;  2KJI A;  1BQT A;  5L3L A;  2DSQ C;  1WQJ I;  1GZZ B; 
#chains in the Genus database with same CATH topology
 2DSP I;  6INS E;  3LRI A;  1IMX A;  1IGL A;  3F2B A;  1ZEI A;  2L29 B;  2GF1 A;  1H59 A;  5L3N A;  4XSS B;  5L3M A;  1TGR A;  2L14 B;  1GZY B;  1H02 B;  3F2C A;  3KR3 D;  3F2D A;  1EFE A;  2JZQ A;  1PMX A;  2KQP A;  2LWZ A;  1B9G A;  1GZR B;  2DSR I;  1SJU A;  3GF1 A;  2KJI A;  1BQT A;  5L3L A;  2DSQ C;  1WQJ I;  1GZZ B; 
#chains in the Genus database with same CATH homology
 2DSP I;  6INS E;  3LRI A;  1IMX A;  1IGL A;  1ZEI A;  2L29 B;  2GF1 A;  1H59 A;  5L3N A;  4XSS B;  5L3M A;  1TGR A;  1GZY B;  1H02 B;  3KR3 D;  1EFE A;  2JZQ A;  1PMX A;  2KQP A;  2LWZ A;  1B9G A;  1GZR B;  2DSR I;  1SJU A;  3GF1 A;  2KJI A;  1BQT A;  5L3L A;  2DSQ C;  1WQJ I;  1GZZ B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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