2L29B

Complex structure of e4 mutant human igf2r domain 11 bound to igf-ii
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
67
structure length
67
Chain Sequence
AYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSRGIVEECCFRSCDLALLETYCATPAKSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transport protein
molecule keywords Insulin-like growth factor 2 receptor variant
publication title An exon splice enhancer primes IGF2:IGF2R binding site structure and function evolution.
pubmed doi rcsb
source organism Homo sapiens
total genus 13
structure length 67
sequence length 67
ec nomenclature
pdb deposition date 2010-08-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 2l29B00
2LWZA 2DSRI 2DSPI 1BQTA 1GZRB 2DSQC 5L3LA 1SJUA 1TGRA 1IMXA 5L3MA 1H59A 1WQJI 3KR3D 3LRIA 2JZQA 5L3NA 4XSSB 1ZEIA 2GF1A 1IGLA 2KJIA 1H02B 2L29B 3GF1A 1EFEA 1B9GA 1GZZB 6INSE 1PMXA 2KQPA 1GZYB
chains in the Genus database with same CATH superfamily
2LWZA 2DSRI 2DSPI 3F2CA 1BQTA 1GZRB 2L14B 2DSQC 5L3LA 3F2BA 1SJUA 3F2DA 1TGRA 1IMXA 5L3MA 1H59A 1WQJI 3KR3D 3LRIA 2JZQA 5L3NA 4XSSB 1ZEIA 2GF1A 1IGLA 2KJIA 1H02B 2L29B 3GF1A 1EFEA 1B9GA 1GZZB 6INSE 1PMXA 2KQPA 1GZYB
chains in the Genus database with same CATH topology
2LWZA 2DSRI 2DSPI 1BQTA 1GZRB 2DSQC 5L3LA 1SJUA 1TGRA 1IMXA 5L3MA 1H59A 1WQJI 3KR3D 3LRIA 2JZQA 5L3NA 4XSSB 1ZEIA 2GF1A 1IGLA 2KJIA 1H02B 2L29B 3GF1A 1EFEA 1B9GA 1GZZB 6INSE 1PMXA 2KQPA 1GZYB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LWZ A;  2DSR I;  2DSP I;  1BQT A;  1GZR B;  2DSQ C;  5L3L A;  1SJU A;  1TGR A;  1IMX A;  5L3M A;  1H59 A;  1WQJ I;  3KR3 D;  3LRI A;  2JZQ A;  5L3N A;  4XSS B;  1ZEI A;  2GF1 A;  1IGL A;  2KJI A;  1H02 B;  2L29 B;  3GF1 A;  1EFE A;  1B9G A;  1GZZ B;  6INS E;  1PMX A;  2KQP A;  1GZY B; 
#chains in the Genus database with same CATH topology
 2LWZ A;  2DSR I;  2DSP I;  3F2C A;  1BQT A;  1GZR B;  2L14 B;  2DSQ C;  5L3L A;  3F2B A;  1SJU A;  3F2D A;  1TGR A;  1IMX A;  5L3M A;  1H59 A;  1WQJ I;  3KR3 D;  3LRI A;  2JZQ A;  5L3N A;  4XSS B;  1ZEI A;  2GF1 A;  1IGL A;  2KJI A;  1H02 B;  2L29 B;  3GF1 A;  1EFE A;  1B9G A;  1GZZ B;  6INS E;  1PMX A;  2KQP A;  1GZY B; 
#chains in the Genus database with same CATH homology
 2LWZ A;  2DSR I;  2DSP I;  1BQT A;  1GZR B;  2DSQ C;  5L3L A;  1SJU A;  1TGR A;  1IMX A;  5L3M A;  1H59 A;  1WQJ I;  3KR3 D;  3LRI A;  2JZQ A;  5L3N A;  4XSS B;  1ZEI A;  2GF1 A;  1IGL A;  2KJI A;  1H02 B;  2L29 B;  3GF1 A;  1EFE A;  1B9G A;  1GZZ B;  6INS E;  1PMX A;  2KQP A;  1GZY B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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