1FWAA

Klebsiella aerogenes urease, c319a variant at ph 7.5
Total Genus 28
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
100
structure length
100
Chain Sequence
MELTPREKDKLLLFTAALVAERRLARGLKLNYPESVALISAFIMEGARDGKSVASLMEEGRHVLTREQVMEGVPEMIPDIQVEATFPDGSKLVTVHNPII
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of Cys319 variants and acetohydroxamate-inhibited Klebsiella aerogenes urease.
pubmed doi rcsb
molecule tags Hydrolase
source organism Klebsiella aerogenes
molecule keywords UREASE
total genus 28
structure length 100
sequence length 100
ec nomenclature ec 3.5.1.5: Urease.
pdb deposition date 1997-04-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00547 Urease_gamma Urease, gamma subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.280.10 Alpha Beta 2-Layer Sandwich Urease; subunit A Urease, gamma-like subunit 1fwaA00
4EP8A 4CEXA 1A5NA 1EJWA 4Z42A 4EPDA 3UBPA 1A5OA 4EPBA 4CEUA 4GOAA 5G4HA 1FWAA 1EJXA 4FURA 1KRCA 1KRBA 1A5KA 5FSEA 2KAUA 2FVHA 1FWFA 3QGKA 4GY7A 1A5LA 4EPEA 1EJSA 1EF2C 1FWIA 1FWHA 1EJTA 1FWEA 1FWJA 1UBPA 3QGAA 1S3TA 1EJRA 1EJUA 1KRAA 1E9YA 1FWGA 2UBPA 1A5MA 3LA4A 1E9ZA 4G7EA 5A6TA 4UBPA 4G7EB 1FWBA 4AC7A 1IE7A 4H9MA 1FWCA 1FWDA 5FSDA 1EJVA
chains in the Genus database with same CATH superfamily
4EP8A 4CEXA 1A5NA 1EJWA 4Z42A 4EPDA 3UBPA 1A5OA 4EPBA 4CEUA 4GOAA 5G4HA 1FWAA 1EJXA 4FURA 1KRCA 1KRBA 1A5KA 5FSEA 2KAUA 2FVHA 1FWFA 3QGKA 4GY7A 1A5LA 4EPEA 1EJSA 1EF2C 1FWIA 1FWHA 1EJTA 1FWEA 1FWJA 1UBPA 3QGAA 1S3TA 1EJRA 1EJUA 1KRAA 1E9YA 1FWGA 2UBPA 1A5MA 3LA4A 1E9ZA 4G7EA 5A6TA 4UBPA 4G7EB 1FWBA 4AC7A 1IE7A 4H9MA 1FWCA 1FWDA 5FSDA 1EJVA
chains in the Genus database with same CATH topology
4EP8A 4CEXA 1A5NA 1EJWA 4Z42A 4EPDA 3UBPA 1A5OA 4EPBA 4CEUA 4GOAA 5G4HA 1FWAA 1EJXA 4FURA 1KRCA 1KRBA 1A5KA 5FSEA 2KAUA 2FVHA 1FWFA 3QGKA 4GY7A 1A5LA 4EPEA 1EJSA 1EF2C 1FWIA 1FWHA 1EJTA 1FWEA 1FWJA 1UBPA 3QGAA 1S3TA 1EJRA 1EJUA 1KRAA 1E9YA 1FWGA 2UBPA 1A5MA 3LA4A 1E9ZA 4G7EA 5A6TA 4UBPA 4G7EB 1FWBA 4AC7A 1IE7A 4H9MA 1FWCA 1FWDA 5FSDA 1EJVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4EP8 A;  4CEX A;  1A5N A;  1EJW A;  4Z42 A;  4EPD A;  3UBP A;  1A5O A;  4EPB A;  4CEU A;  4GOA A;  5G4H A;  1FWA A;  1EJX A;  4FUR A;  1KRC A;  1KRB A;  1A5K A;  5FSE A;  2KAU A;  2FVH A;  1FWF A;  3QGK A;  4GY7 A;  1A5L A;  4EPE A;  1EJS A;  1EF2 C;  1FWI A;  1FWH A;  1EJT A;  1FWE A;  1FWJ A;  1UBP A;  3QGA A;  1S3T A;  1EJR A;  1EJU A;  1KRA A;  1E9Y A;  1FWG A;  2UBP A;  1A5M A;  3LA4 A;  1E9Z A;  4G7E A;  5A6T A;  4UBP A;  4G7E B;  1FWB A;  4AC7 A;  1IE7 A;  4H9M A;  1FWC A;  1FWD A;  5FSD A;  1EJV A; 
#chains in the Genus database with same CATH topology
 4EP8 A;  4CEX A;  1A5N A;  1EJW A;  4Z42 A;  4EPD A;  3UBP A;  1A5O A;  4EPB A;  4CEU A;  4GOA A;  5G4H A;  1FWA A;  1EJX A;  4FUR A;  1KRC A;  1KRB A;  1A5K A;  5FSE A;  2KAU A;  2FVH A;  1FWF A;  3QGK A;  4GY7 A;  1A5L A;  4EPE A;  1EJS A;  1EF2 C;  1FWI A;  1FWH A;  1EJT A;  1FWE A;  1FWJ A;  1UBP A;  3QGA A;  1S3T A;  1EJR A;  1EJU A;  1KRA A;  1E9Y A;  1FWG A;  2UBP A;  1A5M A;  3LA4 A;  1E9Z A;  4G7E A;  5A6T A;  4UBP A;  4G7E B;  1FWB A;  4AC7 A;  1IE7 A;  4H9M A;  1FWC A;  1FWD A;  5FSD A;  1EJV A; 
#chains in the Genus database with same CATH homology
 4EP8 A;  4CEX A;  1A5N A;  1EJW A;  4Z42 A;  4EPD A;  3UBP A;  1A5O A;  4EPB A;  4CEU A;  4GOA A;  5G4H A;  1FWA A;  1EJX A;  4FUR A;  1KRC A;  1KRB A;  1A5K A;  5FSE A;  2KAU A;  2FVH A;  1FWF A;  3QGK A;  4GY7 A;  1A5L A;  4EPE A;  1EJS A;  1EF2 C;  1FWI A;  1FWH A;  1EJT A;  1FWE A;  1FWJ A;  1UBP A;  3QGA A;  1S3T A;  1EJR A;  1EJU A;  1KRA A;  1E9Y A;  1FWG A;  2UBP A;  1A5M A;  3LA4 A;  1E9Z A;  4G7E A;  5A6T A;  4UBP A;  4G7E B;  1FWB A;  4AC7 A;  1IE7 A;  4H9M A;  1FWC A;  1FWD A;  5FSD A;  1EJV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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