4EP8A

Initial urease structure for radiation damage experiment at 100 k
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
100
structure length
100
Chain Sequence
MELTPREKDKLLLFTAALVAERRLARGLKLNYPESVALISAFIMEGARDGKSVASLMEEGRHVLTREQVMEGVPEMIPDIQVEATFPDGSKLVTVHNPII
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase
molecule keywords Urease subunit alpha
publication title Spatial distribution of radiation damage to crystalline proteins at 25-300 K.
pubmed doi rcsb
source organism Enterobacter aerogenes
total genus 30
structure length 100
sequence length 100
ec nomenclature ec 3.5.1.5: Urease.
pdb deposition date 2012-04-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00547 Urease_gamma Urease, gamma subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.280.10 Alpha Beta 2-Layer Sandwich Urease; subunit A Urease, gamma-like subunit 4ep8A00
4EPDA 1EJVA 1E9ZA 1FWBA 1A5OA 1EJUA 4EPBA 5FSEA 1EJRA 4G7EB 3QGAA 4EP8A 1E9YA 1IE7A 4GOAA 5G4HA 3QGKA 5FSDA 4UBPA 4G7EA 1EJXA 1A5KA 1FWFA 3UBPA 1FWAA 4AC7A 1A5MA 4H9MA 4CEUA 4CEXA 1UBPA 3LA4A 2FVHA 4GY7A 5A6TA 1A5NA 1FWEA 2UBPA 4FURA 4EPEA 1FWDA 1KRBA 1FWCA 1EJTA 1EJSA 1FWJA 1KRCA 2KAUA 1EJWA 1S3TA 1FWGA 1FWHA 1A5LA 1KRAA 1EF2C 4Z42A 1FWIA
chains in the Genus database with same CATH superfamily
4EPDA 1EJVA 1E9ZA 1FWBA 1A5OA 1EJUA 4EPBA 5FSEA 1EJRA 4G7EB 3QGAA 4EP8A 1E9YA 1IE7A 4GOAA 5G4HA 3QGKA 5FSDA 4UBPA 4G7EA 1EJXA 1A5KA 1FWFA 3UBPA 1FWAA 4AC7A 1A5MA 4H9MA 4CEUA 4CEXA 1UBPA 3LA4A 2FVHA 4GY7A 5A6TA 1A5NA 1FWEA 2UBPA 4FURA 4EPEA 1FWDA 1KRBA 1FWCA 1EJTA 1EJSA 1FWJA 1KRCA 2KAUA 1EJWA 1S3TA 1FWGA 1FWHA 1A5LA 1KRAA 1EF2C 4Z42A 1FWIA
chains in the Genus database with same CATH topology
4EPDA 1EJVA 1E9ZA 1FWBA 1A5OA 1EJUA 4EPBA 5FSEA 1EJRA 4G7EB 3QGAA 4EP8A 1E9YA 1IE7A 4GOAA 5G4HA 3QGKA 5FSDA 4UBPA 4G7EA 1EJXA 1A5KA 1FWFA 3UBPA 1FWAA 4AC7A 1A5MA 4H9MA 4CEUA 4CEXA 1UBPA 3LA4A 2FVHA 4GY7A 5A6TA 1A5NA 1FWEA 2UBPA 4FURA 4EPEA 1FWDA 1KRBA 1FWCA 1EJTA 1EJSA 1FWJA 1KRCA 2KAUA 1EJWA 1S3TA 1FWGA 1FWHA 1A5LA 1KRAA 1EF2C 4Z42A 1FWIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4EPD A;  1EJV A;  1E9Z A;  1FWB A;  1A5O A;  1EJU A;  4EPB A;  5FSE A;  1EJR A;  4G7E B;  3QGA A;  4EP8 A;  1E9Y A;  1IE7 A;  4GOA A;  5G4H A;  3QGK A;  5FSD A;  4UBP A;  4G7E A;  1EJX A;  1A5K A;  1FWF A;  3UBP A;  1FWA A;  4AC7 A;  1A5M A;  4H9M A;  4CEU A;  4CEX A;  1UBP A;  3LA4 A;  2FVH A;  4GY7 A;  5A6T A;  1A5N A;  1FWE A;  2UBP A;  4FUR A;  4EPE A;  1FWD A;  1KRB A;  1FWC A;  1EJT A;  1EJS A;  1FWJ A;  1KRC A;  2KAU A;  1EJW A;  1S3T A;  1FWG A;  1FWH A;  1A5L A;  1KRA A;  1EF2 C;  4Z42 A;  1FWI A; 
#chains in the Genus database with same CATH topology
 4EPD A;  1EJV A;  1E9Z A;  1FWB A;  1A5O A;  1EJU A;  4EPB A;  5FSE A;  1EJR A;  4G7E B;  3QGA A;  4EP8 A;  1E9Y A;  1IE7 A;  4GOA A;  5G4H A;  3QGK A;  5FSD A;  4UBP A;  4G7E A;  1EJX A;  1A5K A;  1FWF A;  3UBP A;  1FWA A;  4AC7 A;  1A5M A;  4H9M A;  4CEU A;  4CEX A;  1UBP A;  3LA4 A;  2FVH A;  4GY7 A;  5A6T A;  1A5N A;  1FWE A;  2UBP A;  4FUR A;  4EPE A;  1FWD A;  1KRB A;  1FWC A;  1EJT A;  1EJS A;  1FWJ A;  1KRC A;  2KAU A;  1EJW A;  1S3T A;  1FWG A;  1FWH A;  1A5L A;  1KRA A;  1EF2 C;  4Z42 A;  1FWI A; 
#chains in the Genus database with same CATH homology
 4EPD A;  1EJV A;  1E9Z A;  1FWB A;  1A5O A;  1EJU A;  4EPB A;  5FSE A;  1EJR A;  4G7E B;  3QGA A;  4EP8 A;  1E9Y A;  1IE7 A;  4GOA A;  5G4H A;  3QGK A;  5FSD A;  4UBP A;  4G7E A;  1EJX A;  1A5K A;  1FWF A;  3UBP A;  1FWA A;  4AC7 A;  1A5M A;  4H9M A;  4CEU A;  4CEX A;  1UBP A;  3LA4 A;  2FVH A;  4GY7 A;  5A6T A;  1A5N A;  1FWE A;  2UBP A;  4FUR A;  4EPE A;  1FWD A;  1KRB A;  1FWC A;  1EJT A;  1EJS A;  1FWJ A;  1KRC A;  2KAU A;  1EJW A;  1S3T A;  1FWG A;  1FWH A;  1A5L A;  1KRA A;  1EF2 C;  4Z42 A;  1FWI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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