1FWEA

Klebsiella aerogenes urease, c319a variant with acetohydroxamic acid (aha) bound
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
100
structure length
100
Chain Sequence
MELTPREKDKLLLFTAALVAERRLARGLKLNYPESVALISAFIMEGARDGKSVASLMEEGRHVLTREQVMEGVPEMIPDIQVEATFPDGSKLVTVHNPII
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of Cys319 variants and acetohydroxamate-inhibited Klebsiella aerogenes urease.
pubmed doi rcsb
molecule keywords UREASE
molecule tags Hydrolase
source organism Klebsiella aerogenes
total genus 29
structure length 100
sequence length 100
ec nomenclature ec 3.5.1.5: Urease.
pdb deposition date 1997-04-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00547 Urease_gamma Urease, gamma subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.280.10 Alpha Beta 2-Layer Sandwich Urease; subunit A Urease, gamma-like subunit 1fweA00
1EJVA 4EP8A 4FURA 2FVHA 5A6TA 5FSDA 1FWCA 4CEXA 4H9MA 1A5MA 1EF2C 1EJUA 5G4HA 1A5KA 1KRAA 1KRCA 1UBPA 2KAUA 1E9YA 1FWHA 1A5OA 4Z42A 1FWGA 4AC7A 1EJSA 4GY7A 1FWFA 4EPBA 5FSEA 3QGKA 2UBPA 3LA4A 4G7EA 4GOAA 1FWJA 1EJXA 1FWAA 1FWDA 4G7EB 1EJRA 1E9ZA 1EJWA 1KRBA 1A5NA 1IE7A 1FWEA 4CEUA 1FWIA 3UBPA 1EJTA 1FWBA 4UBPA 1A5LA 3QGAA 1S3TA 4EPDA 4EPEA
chains in the Genus database with same CATH superfamily
1EJVA 4EP8A 4FURA 2FVHA 5A6TA 5FSDA 1FWCA 4CEXA 4H9MA 1A5MA 1EF2C 1EJUA 5G4HA 1A5KA 1KRAA 1KRCA 1UBPA 2KAUA 1E9YA 1FWHA 1A5OA 4Z42A 1FWGA 4AC7A 1EJSA 4GY7A 1FWFA 4EPBA 5FSEA 3QGKA 2UBPA 3LA4A 4G7EA 4GOAA 1FWJA 1EJXA 1FWAA 1FWDA 4G7EB 1EJRA 1E9ZA 1EJWA 1KRBA 1A5NA 1IE7A 1FWEA 4CEUA 1FWIA 3UBPA 1EJTA 1FWBA 4UBPA 1A5LA 3QGAA 1S3TA 4EPDA 4EPEA
chains in the Genus database with same CATH topology
1EJVA 4EP8A 4FURA 2FVHA 5A6TA 5FSDA 1FWCA 4CEXA 4H9MA 1A5MA 1EF2C 1EJUA 5G4HA 1A5KA 1KRAA 1KRCA 1UBPA 2KAUA 1E9YA 1FWHA 1A5OA 4Z42A 1FWGA 4AC7A 1EJSA 4GY7A 1FWFA 4EPBA 5FSEA 3QGKA 2UBPA 3LA4A 4G7EA 4GOAA 1FWJA 1EJXA 1FWAA 1FWDA 4G7EB 1EJRA 1E9ZA 1EJWA 1KRBA 1A5NA 1IE7A 1FWEA 4CEUA 1FWIA 3UBPA 1EJTA 1FWBA 4UBPA 1A5LA 3QGAA 1S3TA 4EPDA 4EPEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EJV A;  4EP8 A;  4FUR A;  2FVH A;  5A6T A;  5FSD A;  1FWC A;  4CEX A;  4H9M A;  1A5M A;  1EF2 C;  1EJU A;  5G4H A;  1A5K A;  1KRA A;  1KRC A;  1UBP A;  2KAU A;  1E9Y A;  1FWH A;  1A5O A;  4Z42 A;  1FWG A;  4AC7 A;  1EJS A;  4GY7 A;  1FWF A;  4EPB A;  5FSE A;  3QGK A;  2UBP A;  3LA4 A;  4G7E A;  4GOA A;  1FWJ A;  1EJX A;  1FWA A;  1FWD A;  4G7E B;  1EJR A;  1E9Z A;  1EJW A;  1KRB A;  1A5N A;  1IE7 A;  1FWE A;  4CEU A;  1FWI A;  3UBP A;  1EJT A;  1FWB A;  4UBP A;  1A5L A;  3QGA A;  1S3T A;  4EPD A;  4EPE A; 
#chains in the Genus database with same CATH topology
 1EJV A;  4EP8 A;  4FUR A;  2FVH A;  5A6T A;  5FSD A;  1FWC A;  4CEX A;  4H9M A;  1A5M A;  1EF2 C;  1EJU A;  5G4H A;  1A5K A;  1KRA A;  1KRC A;  1UBP A;  2KAU A;  1E9Y A;  1FWH A;  1A5O A;  4Z42 A;  1FWG A;  4AC7 A;  1EJS A;  4GY7 A;  1FWF A;  4EPB A;  5FSE A;  3QGK A;  2UBP A;  3LA4 A;  4G7E A;  4GOA A;  1FWJ A;  1EJX A;  1FWA A;  1FWD A;  4G7E B;  1EJR A;  1E9Z A;  1EJW A;  1KRB A;  1A5N A;  1IE7 A;  1FWE A;  4CEU A;  1FWI A;  3UBP A;  1EJT A;  1FWB A;  4UBP A;  1A5L A;  3QGA A;  1S3T A;  4EPD A;  4EPE A; 
#chains in the Genus database with same CATH homology
 1EJV A;  4EP8 A;  4FUR A;  2FVH A;  5A6T A;  5FSD A;  1FWC A;  4CEX A;  4H9M A;  1A5M A;  1EF2 C;  1EJU A;  5G4H A;  1A5K A;  1KRA A;  1KRC A;  1UBP A;  2KAU A;  1E9Y A;  1FWH A;  1A5O A;  4Z42 A;  1FWG A;  4AC7 A;  1EJS A;  4GY7 A;  1FWF A;  4EPB A;  5FSE A;  3QGK A;  2UBP A;  3LA4 A;  4G7E A;  4GOA A;  1FWJ A;  1EJX A;  1FWA A;  1FWD A;  4G7E B;  1EJR A;  1E9Z A;  1EJW A;  1KRB A;  1A5N A;  1IE7 A;  1FWE A;  4CEU A;  1FWI A;  3UBP A;  1EJT A;  1FWB A;  4UBP A;  1A5L A;  3QGA A;  1S3T A;  4EPD A;  4EPE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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