1P6DA

Structure of the d55n mutant of phospholipase c from bacillus cereus in complex with (3s)-3,4,di-n-hexanoyloxybutyl-1-phosphocholine
Total Genus 105
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
245
structure length
245
Chain Sequence
WSAEDKHKEGVNSHLWIVNRAIDIMSRNTTLVKQDRVAQLNEWRTELENGIYAANYENPYYDNSTFASHFYDPDNGKTYIPFAKQAKETGAKYFKLAGESYKNKDMKQAFFYLGLSLHYLGDVNQPMHAANFTNLSYPQGFHSKYENFVDTIKDNYKVTDGNGYWNWKGTNPEEWIHGAAVVAKQDYSGIVNDNTKDWFVKAAVSQEYADKWRAEVTPMTGKRLMDAQRVTAGYIQLWFDTYGDR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Using X-ray crystallography of the Asp55Asn mutant of the phosphatidylcholine-preferring phospholipase C from Bacillus cereus to support the mechanistic role of Asp55 as the general base.
pubmed doi rcsb
molecule tags Hydrolase
source organism Bacillus cereus
molecule keywords PHOSPHOLIPASE C
total genus 105
structure length 245
sequence length 245
ec nomenclature ec 3.1.4.3: Phospholipase C.
pdb deposition date 2003-04-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00882 Zn_dep_PLPC Zinc dependent phospholipase C
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.575.10 Mainly Alpha Orthogonal Bundle P1 Nuclease P1 Nuclease 1p6dA00
3SNGA 2FFZA 1P5XA 1KHOA 5FBCA 4CXPA 2WXTA 1OLPA 3W52A 5FBAA 2WXUA 2FGNA 1GYGA 4DJ4A 4JDGA 2WY6A 5FBGA 5FB9A 1CA1A 1P6EA 4CXOA 4CXVA 1P6DA 1AH7A 1AK0A 1QMDA 5FBBA 5FBDA 1QM6A 4CWMA 2HUCA 5FBFA
chains in the Genus database with same CATH superfamily
3SNGA 2FFZA 1P5XA 1KHOA 5FBCA 4CXPA 2WXTA 1OLPA 3W52A 5FBAA 2WXUA 2FGNA 1GYGA 4DJ4A 4JDGA 2WY6A 5FBGA 5FB9A 1CA1A 1P6EA 4CXOA 4CXVA 1P6DA 1AH7A 1AK0A 1QMDA 5FBBA 5FBDA 1QM6A 4CWMA 2HUCA 5FBFA
chains in the Genus database with same CATH topology
3SNGA 2FFZA 1P5XA 1KHOA 5FBCA 4CXPA 2WXTA 1OLPA 3W52A 5FBAA 2WXUA 2FGNA 1GYGA 4DJ4A 4JDGA 2WY6A 5FBGA 5FB9A 1CA1A 1P6EA 4CXOA 4CXVA 1P6DA 1AH7A 1AK0A 1QMDA 5FBBA 5FBDA 1QM6A 4CWMA 2HUCA 5FBFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3SNG A;  2FFZ A;  1P5X A;  1KHO A;  5FBC A;  4CXP A;  2WXT A;  1OLP A;  3W52 A;  5FBA A;  2WXU A;  2FGN A;  1GYG A;  4DJ4 A;  4JDG A;  2WY6 A;  5FBG A;  5FB9 A;  1CA1 A;  1P6E A;  4CXO A;  4CXV A;  1P6D A;  1AH7 A;  1AK0 A;  1QMD A;  5FBB A;  5FBD A;  1QM6 A;  4CWM A;  2HUC A;  5FBF A; 
#chains in the Genus database with same CATH topology
 3SNG A;  2FFZ A;  1P5X A;  1KHO A;  5FBC A;  4CXP A;  2WXT A;  1OLP A;  3W52 A;  5FBA A;  2WXU A;  2FGN A;  1GYG A;  4DJ4 A;  4JDG A;  2WY6 A;  5FBG A;  5FB9 A;  1CA1 A;  1P6E A;  4CXO A;  4CXV A;  1P6D A;  1AH7 A;  1AK0 A;  1QMD A;  5FBB A;  5FBD A;  1QM6 A;  4CWM A;  2HUC A;  5FBF A; 
#chains in the Genus database with same CATH homology
 3SNG A;  2FFZ A;  1P5X A;  1KHO A;  5FBC A;  4CXP A;  2WXT A;  1OLP A;  3W52 A;  5FBA A;  2WXU A;  2FGN A;  1GYG A;  4DJ4 A;  4JDG A;  2WY6 A;  5FBG A;  5FB9 A;  1CA1 A;  1P6E A;  4CXO A;  4CXV A;  1P6D A;  1AH7 A;  1AK0 A;  1QMD A;  5FBB A;  5FBD A;  1QM6 A;  4CWM A;  2HUC A;  5FBF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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