2WY6A

Clostridium perfringens alpha-toxin strain nctc8237 mutant t74i
Total Genus 125
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
125
sequence length
370
structure length
361
Chain Sequence
WDGKIDGTGTHAMIVTQGVSILENDLSKNEPESVRKNLEILKENMHELQLGSTYPDYDKNAYDLYQDHFWDPDIDNSWYLAYSIPDTGESQIRKFSALARYEWQRGNYKQATFYLGEAMHYFGDIDTPYHPANVTAVDSAGHVKFETFAEERKEQYKINTAGCKTNEAFYTDILKNKDFNAWSKEYARGFAKTGKSIYYSHASMSHSWDDWDYAAKVTLANSQKGTAGYIYRFLHDVSEGNDPKNVKELVAYISTSGEKDAGTDDYMYFGIKTKDGKTQEWEMDNPGNDFMTGSKDTYTFKLKDENLKIDDIQNMWIRKRKYTAFPDAYKPENIKIIANGKVVVDKDINEWISGNSTYNIK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Comparison of a Nontoxic Variant of Clostridium Perfringens [Alpha]-Toxin with the Toxic Wild-Type Strain
pubmed doi rcsb
molecule tags Hydrolase
source organism Clostridium perfringens
molecule keywords PHOSPHOLIPASE C
total genus 125
structure length 361
sequence length 370
chains with identical sequence B, C
ec nomenclature ec 3.1.4.3: Phospholipase C.
pdb deposition date 2009-11-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00882 Zn_dep_PLPC Zinc dependent phospholipase C
A PF01477 PLAT PLAT/LH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.575.10 Mainly Alpha Orthogonal Bundle P1 Nuclease P1 Nuclease 2wy6A01
2.60.60.20 Mainly Beta Sandwich Lipoxygenase-1 PLAT/LH2 domain 2wy6A02
3VF1A 1ROVA 3BNBA 2FFZA 1LPAB 4DJ4A 1FGRA 1F8NA 1FGQA 1LNHA 1FGOA 2P0MA 1P6EA 5FBAA 1YGEA 3BNCA 3V99A 5EEOA 1KHOA 1CA1A 2OXEA 4WHAA 3O8YA 1QMDA 4CXPA 1LPBB 1RRLA 1N8SA 4CWMA 1ETHA 4CXOA 4QWTA 1P5XA 2WY6A 3FG3A 2WXUA 4WFOA 1P6DA 3W52A 4JDGA 1LOXA 2HUCA 1FGTA 1AK0A 3BNDA 1HU9A 5FBFA 2WXTA 1Y4KA 3V98A 1JNQA 2PVSA 1NO3A 1IK3A 1HPLA 3SNGA 3PZWA 1AH7A 3FG1A 1QM6A 1W52X 1FGMA 1N8QA 3V92A 3CWZB 1GPLA 4NREA 5FB9A 1RP1A 5FBBA 1OLPA 5FBDA 5FBCA 3BNEA 3FG4A 1BU8A 2FGNA 1GYGA 2IUKA 2PPLA 2SBLA 2IUJA 5FBGA 2FNQA 4CXVA 1RRHA
chains in the Genus database with same CATH superfamily
3VF1A 1ROVA 3BNBA 2FFZA 1LPAB 4DJ4A 1FGRA 3U6GA 2KXTA 1F8NA 1FGQA 1LNHA 1FGOA 2P0MA 1P6EA 2QNGA 5FBAA 2XHJA 1YGEA 3BNCA 3V99A 2QZ7A 5EEOA 1KHOA 1CA1A 2OXEA 4QEYA 4WHAA 3O8YA 1QMDA 4CXPA 1LPBB 1RRLA 2XHHA 1N8SA 4CWMA 1ETHA 4CXOA 4QWTA 3IBZA 1P5XA 2WY6A 3FG3A 2WXUA 4WFOA 1P6DA 3W52A 4JDGA 1LOXA 2HUCA 1FGTA 1AK0A 3BNDA 1HU9A 5FBFA 2WXTA 1Y4KA 3V98A 1JNQA 2LRGA 2PVSA 1NO3A 1IK3A 1HPLA 3SNGA 3PZWA 1AH7A 3FG1A 1QM6A 1W52X 1FGMA 1N8QA 3V92A 3CWZB 1GPLA 4NREA 5FB9A 1RP1A 5FBBA 1OLPA 5FBDA 5FBCA 3BNEA 2LG7A 3FG4A 2XFEA 1BU8A 2FGNA 2XFDA 1GYGA 2IUKA 2PPLA 2SBLA 2IUJA 5FBGA 2KXVA 2FNQA 4CXVA 1RRHA 2LGEA
chains in the Genus database with same CATH topology
3VF1A 1ROVA 3BNBA 2FFZA 1LPAB 4DJ4A 1FGRA 1F8NA 1FGQA 1LNHA 1FGOA 2P0MA 1P6EA 5FBAA 1YGEA 3BNCA 3V99A 5EEOA 1KHOA 1CA1A 2OXEA 4WHAA 3O8YA 1QMDA 4CXPA 1LPBB 1RRLA 1N8SA 4CWMA 1ETHA 4CXOA 4QWTA 1P5XA 2WY6A 3FG3A 2WXUA 4WFOA 1P6DA 3W52A 4JDGA 1LOXA 2HUCA 1FGTA 1AK0A 3BNDA 1HU9A 5FBFA 2WXTA 1Y4KA 3V98A 1JNQA 2PVSA 1NO3A 1IK3A 1HPLA 3SNGA 3PZWA 1AH7A 3FG1A 1QM6A 1W52X 1FGMA 1N8QA 3V92A 3CWZB 1GPLA 4NREA 5FB9A 1RP1A 5FBBA 1OLPA 5FBDA 5FBCA 3BNEA 3FG4A 1BU8A 2FGNA 1GYGA 2IUKA 2PPLA 2SBLA 2IUJA 5FBGA 2FNQA 4CXVA 1RRHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3VF1 A;  1ROV A;  3BNB A;  2FFZ A;  1LPA B;  4DJ4 A;  1FGR A;  1F8N A;  1FGQ A;  1LNH A;  1FGO A;  2P0M A;  1P6E A;  5FBA A;  1YGE A;  3BNC A;  3V99 A;  5EEO A;  1KHO A;  1CA1 A;  2OXE A;  4WHA A;  3O8Y A;  1QMD A;  4CXP A;  1LPB B;  1RRL A;  1N8S A;  4CWM A;  1ETH A;  4CXO A;  4QWT A;  1P5X A;  2WY6 A;  3FG3 A;  2WXU A;  4WFO A;  1P6D A;  3W52 A;  4JDG A;  1LOX A;  2HUC A;  1FGT A;  1AK0 A;  3BND A;  1HU9 A;  5FBF A;  2WXT A;  1Y4K A;  3V98 A;  1JNQ A;  2PVS A;  1NO3 A;  1IK3 A;  1HPL A;  3SNG A;  3PZW A;  1AH7 A;  3FG1 A;  1QM6 A;  1W52 X;  1FGM A;  1N8Q A;  3V92 A;  3CWZ B;  1GPL A;  4NRE A;  5FB9 A;  1RP1 A;  5FBB A;  1OLP A;  5FBD A;  5FBC A;  3BNE A;  3FG4 A;  1BU8 A;  2FGN A;  1GYG A;  2IUK A;  2PPL A;  2SBL A;  2IUJ A;  5FBG A;  2FNQ A;  4CXV A;  1RRH A; 
#chains in the Genus database with same CATH topology
 3VF1 A;  1ROV A;  3BNB A;  2FFZ A;  1LPA B;  4DJ4 A;  1FGR A;  3U6G A;  2KXT A;  1F8N A;  1FGQ A;  1LNH A;  1FGO A;  2P0M A;  1P6E A;  2QNG A;  5FBA A;  2XHJ A;  1YGE A;  3BNC A;  3V99 A;  2QZ7 A;  5EEO A;  1KHO A;  1CA1 A;  2OXE A;  4QEY A;  4WHA A;  3O8Y A;  1QMD A;  4CXP A;  1LPB B;  1RRL A;  2XHH A;  1N8S A;  4CWM A;  1ETH A;  4CXO A;  4QWT A;  3IBZ A;  1P5X A;  2WY6 A;  3FG3 A;  2WXU A;  4WFO A;  1P6D A;  3W52 A;  4JDG A;  1LOX A;  2HUC A;  1FGT A;  1AK0 A;  3BND A;  1HU9 A;  5FBF A;  2WXT A;  1Y4K A;  3V98 A;  1JNQ A;  2LRG A;  2PVS A;  1NO3 A;  1IK3 A;  1HPL A;  3SNG A;  3PZW A;  1AH7 A;  3FG1 A;  1QM6 A;  1W52 X;  1FGM A;  1N8Q A;  3V92 A;  3CWZ B;  1GPL A;  4NRE A;  5FB9 A;  1RP1 A;  5FBB A;  1OLP A;  5FBD A;  5FBC A;  3BNE A;  2LG7 A;  3FG4 A;  2XFE A;  1BU8 A;  2FGN A;  2XFD A;  1GYG A;  2IUK A;  2PPL A;  2SBL A;  2IUJ A;  5FBG A;  2KXV A;  2FNQ A;  4CXV A;  1RRH A;  2LGE A; 
#chains in the Genus database with same CATH homology
 3VF1 A;  1ROV A;  3BNB A;  2FFZ A;  1LPA B;  4DJ4 A;  1FGR A;  1F8N A;  1FGQ A;  1LNH A;  1FGO A;  2P0M A;  1P6E A;  5FBA A;  1YGE A;  3BNC A;  3V99 A;  5EEO A;  1KHO A;  1CA1 A;  2OXE A;  4WHA A;  3O8Y A;  1QMD A;  4CXP A;  1LPB B;  1RRL A;  1N8S A;  4CWM A;  1ETH A;  4CXO A;  4QWT A;  1P5X A;  2WY6 A;  3FG3 A;  2WXU A;  4WFO A;  1P6D A;  3W52 A;  4JDG A;  1LOX A;  2HUC A;  1FGT A;  1AK0 A;  3BND A;  1HU9 A;  5FBF A;  2WXT A;  1Y4K A;  3V98 A;  1JNQ A;  2PVS A;  1NO3 A;  1IK3 A;  1HPL A;  3SNG A;  3PZW A;  1AH7 A;  3FG1 A;  1QM6 A;  1W52 X;  1FGM A;  1N8Q A;  3V92 A;  3CWZ B;  1GPL A;  4NRE A;  5FB9 A;  1RP1 A;  5FBB A;  1OLP A;  5FBD A;  5FBC A;  3BNE A;  3FG4 A;  1BU8 A;  2FGN A;  1GYG A;  2IUK A;  2PPL A;  2SBL A;  2IUJ A;  5FBG A;  2FNQ A;  4CXV A;  1RRH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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