2WXTA

Clostridium perfringens alpha-toxin strain nctc8237
Total Genus 134
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
134
sequence length
370
structure length
359
Chain Sequence
WDGKIDGTGTHAMIVTQGVSILENDLSKNEPESVRKNLEILKENMHELQLGSTYPDYDKNAYDLYQDHFWDPDTLAYSIPDTGESQIRKFSALARYEWQRGNYKQATFYLGEAMHYFGDIDTPYHPANVTAVDSAGHVKFETFAEERKEQYKINTAGCKTNEAFYTDILKNKDFNAWSKEYARGFAKTGKSIYYSHASMSHSWDDWDYAAKVTLANSQKGTAGYIYRFLHDVSEGNDPSVGKNVKELVAYISTSGEKDAGTDDYMYFGIKTKDGKTQEWEMDNPGNDFMTGSKDTYTFKLKDENLKIDDIQNMWIRKRKYTAFSDAYKPENIKIIANGKVVVDKDINEWISGNSTYNIK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Comparison of a Nontoxic Variant of Clostridium Perfringens [Alpha]-Toxin with the Toxic Wild-Type Strain
pubmed doi rcsb
molecule tags Hydrolase
source organism Clostridium perfringens
molecule keywords PHOSPHOLIPASE C
total genus 134
structure length 359
sequence length 370
ec nomenclature ec 3.1.4.3: Phospholipase C.
pdb deposition date 2009-11-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00882 Zn_dep_PLPC Zinc dependent phospholipase C
A PF01477 PLAT PLAT/LH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.575.10 Mainly Alpha Orthogonal Bundle P1 Nuclease P1 Nuclease 2wxtA01
2.60.60.20 Mainly Beta Sandwich Lipoxygenase-1 PLAT/LH2 domain 2wxtA02
3O8YA 3CWZB 1OLPA 2PPLA 1P6DA 3BNEA 4CXOA 1RP1A 4CXPA 1ETHA 2FGNA 2HUCA 5FBCA 2OXEA 1N8QA 4CXVA 2WXUA 1LPBB 1FGMA 1NO3A 1W52X 1QMDA 3BNCA 1Y4KA 1YGEA 3W52A 5EEOA 2IUKA 2WY6A 4JDGA 5FBGA 3VF1A 1HU9A 1F8NA 1P6EA 4WFOA 1CA1A 1GYGA 3BNDA 1FGOA 5FB9A 3FG3A 2FNQA 4QWTA 3V99A 1FGQA 3SNGA 2SBLA 1P5XA 1KHOA 5FBDA 2P0MA 1FGRA 3V98A 1LPAB 1HPLA 5FBFA 1AK0A 3FG4A 1QM6A 2WXTA 3BNBA 1RRHA 5FBAA 1IK3A 1JNQA 1AH7A 1GPLA 3V92A 1BU8A 4DJ4A 1ROVA 1N8SA 4WHAA 1LOXA 1RRLA 1FGTA 4NREA 2IUJA 5FBBA 1LNHA 3PZWA 4CWMA 3FG1A 2PVSA 2FFZA
chains in the Genus database with same CATH superfamily
3O8YA 3CWZB 1OLPA 2PPLA 1P6DA 3BNEA 4CXOA 1RP1A 4CXPA 2XHJA 4QEYA 3U6GA 1ETHA 2LG7A 2FGNA 2HUCA 5FBCA 2OXEA 1N8QA 4CXVA 2WXUA 1LPBB 1FGMA 1NO3A 2KXVA 1W52X 2LGEA 1QMDA 3BNCA 1Y4KA 1YGEA 3W52A 5EEOA 2IUKA 2WY6A 4JDGA 5FBGA 3VF1A 1HU9A 1F8NA 1P6EA 4WFOA 1CA1A 1GYGA 3BNDA 1FGOA 5FB9A 2QZ7A 3FG3A 2FNQA 4QWTA 3V99A 1FGQA 3SNGA 2SBLA 1P5XA 3IBZA 1KHOA 5FBDA 2P0MA 1FGRA 3V98A 1LPAB 1HPLA 2XFDA 5FBFA 1AK0A 3FG4A 1QM6A 2QNGA 2WXTA 3BNBA 2XFEA 1RRHA 5FBAA 2KXTA 1IK3A 1JNQA 1AH7A 1GPLA 2XHHA 3V92A 1BU8A 4DJ4A 1ROVA 1N8SA 4WHAA 1LOXA 1RRLA 2LRGA 1FGTA 4NREA 2IUJA 5FBBA 1LNHA 3PZWA 4CWMA 3FG1A 2PVSA 2FFZA
chains in the Genus database with same CATH topology
3O8YA 3CWZB 1OLPA 2PPLA 1P6DA 3BNEA 4CXOA 1RP1A 4CXPA 1ETHA 2FGNA 2HUCA 5FBCA 2OXEA 1N8QA 4CXVA 2WXUA 1LPBB 1FGMA 1NO3A 1W52X 1QMDA 3BNCA 1Y4KA 1YGEA 3W52A 5EEOA 2IUKA 2WY6A 4JDGA 5FBGA 3VF1A 1HU9A 1F8NA 1P6EA 4WFOA 1CA1A 1GYGA 3BNDA 1FGOA 5FB9A 3FG3A 2FNQA 4QWTA 3V99A 1FGQA 3SNGA 2SBLA 1P5XA 1KHOA 5FBDA 2P0MA 1FGRA 3V98A 1LPAB 1HPLA 5FBFA 1AK0A 3FG4A 1QM6A 2WXTA 3BNBA 1RRHA 5FBAA 1IK3A 1JNQA 1AH7A 1GPLA 3V92A 1BU8A 4DJ4A 1ROVA 1N8SA 4WHAA 1LOXA 1RRLA 1FGTA 4NREA 2IUJA 5FBBA 1LNHA 3PZWA 4CWMA 3FG1A 2PVSA 2FFZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3O8Y A;  3CWZ B;  1OLP A;  2PPL A;  1P6D A;  3BNE A;  4CXO A;  1RP1 A;  4CXP A;  1ETH A;  2FGN A;  2HUC A;  5FBC A;  2OXE A;  1N8Q A;  4CXV A;  2WXU A;  1LPB B;  1FGM A;  1NO3 A;  1W52 X;  1QMD A;  3BNC A;  1Y4K A;  1YGE A;  3W52 A;  5EEO A;  2IUK A;  2WY6 A;  4JDG A;  5FBG A;  3VF1 A;  1HU9 A;  1F8N A;  1P6E A;  4WFO A;  1CA1 A;  1GYG A;  3BND A;  1FGO A;  5FB9 A;  3FG3 A;  2FNQ A;  4QWT A;  3V99 A;  1FGQ A;  3SNG A;  2SBL A;  1P5X A;  1KHO A;  5FBD A;  2P0M A;  1FGR A;  3V98 A;  1LPA B;  1HPL A;  5FBF A;  1AK0 A;  3FG4 A;  1QM6 A;  2WXT A;  3BNB A;  1RRH A;  5FBA A;  1IK3 A;  1JNQ A;  1AH7 A;  1GPL A;  3V92 A;  1BU8 A;  4DJ4 A;  1ROV A;  1N8S A;  4WHA A;  1LOX A;  1RRL A;  1FGT A;  4NRE A;  2IUJ A;  5FBB A;  1LNH A;  3PZW A;  4CWM A;  3FG1 A;  2PVS A;  2FFZ A; 
#chains in the Genus database with same CATH topology
 3O8Y A;  3CWZ B;  1OLP A;  2PPL A;  1P6D A;  3BNE A;  4CXO A;  1RP1 A;  4CXP A;  2XHJ A;  4QEY A;  3U6G A;  1ETH A;  2LG7 A;  2FGN A;  2HUC A;  5FBC A;  2OXE A;  1N8Q A;  4CXV A;  2WXU A;  1LPB B;  1FGM A;  1NO3 A;  2KXV A;  1W52 X;  2LGE A;  1QMD A;  3BNC A;  1Y4K A;  1YGE A;  3W52 A;  5EEO A;  2IUK A;  2WY6 A;  4JDG A;  5FBG A;  3VF1 A;  1HU9 A;  1F8N A;  1P6E A;  4WFO A;  1CA1 A;  1GYG A;  3BND A;  1FGO A;  5FB9 A;  2QZ7 A;  3FG3 A;  2FNQ A;  4QWT A;  3V99 A;  1FGQ A;  3SNG A;  2SBL A;  1P5X A;  3IBZ A;  1KHO A;  5FBD A;  2P0M A;  1FGR A;  3V98 A;  1LPA B;  1HPL A;  2XFD A;  5FBF A;  1AK0 A;  3FG4 A;  1QM6 A;  2QNG A;  2WXT A;  3BNB A;  2XFE A;  1RRH A;  5FBA A;  2KXT A;  1IK3 A;  1JNQ A;  1AH7 A;  1GPL A;  2XHH A;  3V92 A;  1BU8 A;  4DJ4 A;  1ROV A;  1N8S A;  4WHA A;  1LOX A;  1RRL A;  2LRG A;  1FGT A;  4NRE A;  2IUJ A;  5FBB A;  1LNH A;  3PZW A;  4CWM A;  3FG1 A;  2PVS A;  2FFZ A; 
#chains in the Genus database with same CATH homology
 3O8Y A;  3CWZ B;  1OLP A;  2PPL A;  1P6D A;  3BNE A;  4CXO A;  1RP1 A;  4CXP A;  1ETH A;  2FGN A;  2HUC A;  5FBC A;  2OXE A;  1N8Q A;  4CXV A;  2WXU A;  1LPB B;  1FGM A;  1NO3 A;  1W52 X;  1QMD A;  3BNC A;  1Y4K A;  1YGE A;  3W52 A;  5EEO A;  2IUK A;  2WY6 A;  4JDG A;  5FBG A;  3VF1 A;  1HU9 A;  1F8N A;  1P6E A;  4WFO A;  1CA1 A;  1GYG A;  3BND A;  1FGO A;  5FB9 A;  3FG3 A;  2FNQ A;  4QWT A;  3V99 A;  1FGQ A;  3SNG A;  2SBL A;  1P5X A;  1KHO A;  5FBD A;  2P0M A;  1FGR A;  3V98 A;  1LPA B;  1HPL A;  5FBF A;  1AK0 A;  3FG4 A;  1QM6 A;  2WXT A;  3BNB A;  1RRH A;  5FBA A;  1IK3 A;  1JNQ A;  1AH7 A;  1GPL A;  3V92 A;  1BU8 A;  4DJ4 A;  1ROV A;  1N8S A;  4WHA A;  1LOX A;  1RRL A;  1FGT A;  4NRE A;  2IUJ A;  5FBB A;  1LNH A;  3PZW A;  4CWM A;  3FG1 A;  2PVS A;  2FFZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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