2WXTA

Clostridium perfringens alpha-toxin strain nctc8237
Total Genus 134
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
134
sequence length
370
structure length
359
Chain Sequence
WDGKIDGTGTHAMIVTQGVSILENDLSKNEPESVRKNLEILKENMHELQLGSTYPDYDKNAYDLYQDHFWDPDTLAYSIPDTGESQIRKFSALARYEWQRGNYKQATFYLGEAMHYFGDIDTPYHPANVTAVDSAGHVKFETFAEERKEQYKINTAGCKTNEAFYTDILKNKDFNAWSKEYARGFAKTGKSIYYSHASMSHSWDDWDYAAKVTLANSQKGTAGYIYRFLHDVSEGNDPSVGKNVKELVAYISTSGEKDAGTDDYMYFGIKTKDGKTQEWEMDNPGNDFMTGSKDTYTFKLKDENLKIDDIQNMWIRKRKYTAFSDAYKPENIKIIANGKVVVDKDINEWISGNSTYNIK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Comparison of a Nontoxic Variant of Clostridium Perfringens [Alpha]-Toxin with the Toxic Wild-Type Strain
pubmed doi rcsb
source organism Clostridium perfringens
molecule tags Hydrolase
molecule keywords PHOSPHOLIPASE C
total genus 134
structure length 359
sequence length 370
ec nomenclature ec 3.1.4.3: Phospholipase C.
pdb deposition date 2009-11-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00882 Zn_dep_PLPC Zinc dependent phospholipase C
A PF01477 PLAT PLAT/LH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.575.10 Mainly Alpha Orthogonal Bundle P1 Nuclease P1 Nuclease 2wxtA01
2.60.60.20 Mainly Beta Sandwich Lipoxygenase-1 PLAT/LH2 domain 2wxtA02
4JDGA 1GYGA 1HU9A 1RRHA 1ROVA 4QWTA 1LPAB 2OXEA 3FG3A 1RP1A 3V98A 1RRLA 1YGEA 3FG4A 1QMDA 3O8YA 5FBAA 2IUKA 3BNCA 2PPLA 3VF1A 3BNBA 1P6DA 5EEOA 1ETHA 1HPLA 3PZWA 4WFOA 4CXVA 2FFZA 1LPBB 1CA1A 2WY6A 1FGRA 5FBFA 3W52A 3V92A 4CXPA 3CWZB 1FGOA 2P0MA 2FGNA 5FBDA 5FB9A 2PVSA 5FBCA 3FG1A 2FNQA 3V99A 1KHOA 4CWMA 1P6EA 3SNGA 1NO3A 1JNQA 4WHAA 4DJ4A 1FGQA 1Y4KA 1FGMA 1AK0A 4CXOA 1P5XA 1W52X 1FGTA 2IUJA 4NREA 3BNEA 1QM6A 1BU8A 1IK3A 1LNHA 5FBBA 2WXUA 2WXTA 2SBLA 1AH7A 3BNDA 1OLPA 5FBGA 1F8NA 1GPLA 1N8SA 1LOXA 1N8QA 2HUCA
chains in the Genus database with same CATH superfamily
4JDGA 1GYGA 1HU9A 1RRHA 1ROVA 2KXVA 4QWTA 2XHHA 2LRGA 1LPAB 2OXEA 3FG3A 1RP1A 3V98A 1RRLA 1YGEA 3FG4A 1QMDA 3O8YA 5FBAA 2IUKA 3BNCA 2PPLA 3VF1A 3BNBA 1P6DA 5EEOA 1ETHA 1HPLA 3PZWA 4WFOA 2QNGA 4CXVA 2FFZA 1LPBB 3IBZA 2QZ7A 1CA1A 2WY6A 1FGRA 5FBFA 3W52A 3V92A 4CXPA 3CWZB 2XHJA 1FGOA 2P0MA 2FGNA 5FBDA 5FB9A 2PVSA 5FBCA 3FG1A 2FNQA 4QEYA 3V99A 1KHOA 4CWMA 1P6EA 3SNGA 2XFEA 2LG7A 1NO3A 1JNQA 4WHAA 4DJ4A 1FGQA 1Y4KA 1FGMA 1AK0A 2XFDA 4CXOA 1P5XA 1W52X 1FGTA 2IUJA 4NREA 3BNEA 1QM6A 1BU8A 1IK3A 3U6GA 2KXTA 1LNHA 5FBBA 2WXUA 2WXTA 2SBLA 1AH7A 3BNDA 1OLPA 5FBGA 1F8NA 1GPLA 2LGEA 1N8SA 1LOXA 1N8QA 2HUCA
chains in the Genus database with same CATH topology
4JDGA 1GYGA 1HU9A 1RRHA 1ROVA 4QWTA 1LPAB 2OXEA 3FG3A 1RP1A 3V98A 1RRLA 1YGEA 3FG4A 1QMDA 3O8YA 5FBAA 2IUKA 3BNCA 2PPLA 3VF1A 3BNBA 1P6DA 5EEOA 1ETHA 1HPLA 3PZWA 4WFOA 4CXVA 2FFZA 1LPBB 1CA1A 2WY6A 1FGRA 5FBFA 3W52A 3V92A 4CXPA 3CWZB 1FGOA 2P0MA 2FGNA 5FBDA 5FB9A 2PVSA 5FBCA 3FG1A 2FNQA 3V99A 1KHOA 4CWMA 1P6EA 3SNGA 1NO3A 1JNQA 4WHAA 4DJ4A 1FGQA 1Y4KA 1FGMA 1AK0A 4CXOA 1P5XA 1W52X 1FGTA 2IUJA 4NREA 3BNEA 1QM6A 1BU8A 1IK3A 1LNHA 5FBBA 2WXUA 2WXTA 2SBLA 1AH7A 3BNDA 1OLPA 5FBGA 1F8NA 1GPLA 1N8SA 1LOXA 1N8QA 2HUCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JDG A;  1GYG A;  1HU9 A;  1RRH A;  1ROV A;  4QWT A;  1LPA B;  2OXE A;  3FG3 A;  1RP1 A;  3V98 A;  1RRL A;  1YGE A;  3FG4 A;  1QMD A;  3O8Y A;  5FBA A;  2IUK A;  3BNC A;  2PPL A;  3VF1 A;  3BNB A;  1P6D A;  5EEO A;  1ETH A;  1HPL A;  3PZW A;  4WFO A;  4CXV A;  2FFZ A;  1LPB B;  1CA1 A;  2WY6 A;  1FGR A;  5FBF A;  3W52 A;  3V92 A;  4CXP A;  3CWZ B;  1FGO A;  2P0M A;  2FGN A;  5FBD A;  5FB9 A;  2PVS A;  5FBC A;  3FG1 A;  2FNQ A;  3V99 A;  1KHO A;  4CWM A;  1P6E A;  3SNG A;  1NO3 A;  1JNQ A;  4WHA A;  4DJ4 A;  1FGQ A;  1Y4K A;  1FGM A;  1AK0 A;  4CXO A;  1P5X A;  1W52 X;  1FGT A;  2IUJ A;  4NRE A;  3BNE A;  1QM6 A;  1BU8 A;  1IK3 A;  1LNH A;  5FBB A;  2WXU A;  2WXT A;  2SBL A;  1AH7 A;  3BND A;  1OLP A;  5FBG A;  1F8N A;  1GPL A;  1N8S A;  1LOX A;  1N8Q A;  2HUC A; 
#chains in the Genus database with same CATH topology
 4JDG A;  1GYG A;  1HU9 A;  1RRH A;  1ROV A;  2KXV A;  4QWT A;  2XHH A;  2LRG A;  1LPA B;  2OXE A;  3FG3 A;  1RP1 A;  3V98 A;  1RRL A;  1YGE A;  3FG4 A;  1QMD A;  3O8Y A;  5FBA A;  2IUK A;  3BNC A;  2PPL A;  3VF1 A;  3BNB A;  1P6D A;  5EEO A;  1ETH A;  1HPL A;  3PZW A;  4WFO A;  2QNG A;  4CXV A;  2FFZ A;  1LPB B;  3IBZ A;  2QZ7 A;  1CA1 A;  2WY6 A;  1FGR A;  5FBF A;  3W52 A;  3V92 A;  4CXP A;  3CWZ B;  2XHJ A;  1FGO A;  2P0M A;  2FGN A;  5FBD A;  5FB9 A;  2PVS A;  5FBC A;  3FG1 A;  2FNQ A;  4QEY A;  3V99 A;  1KHO A;  4CWM A;  1P6E A;  3SNG A;  2XFE A;  2LG7 A;  1NO3 A;  1JNQ A;  4WHA A;  4DJ4 A;  1FGQ A;  1Y4K A;  1FGM A;  1AK0 A;  2XFD A;  4CXO A;  1P5X A;  1W52 X;  1FGT A;  2IUJ A;  4NRE A;  3BNE A;  1QM6 A;  1BU8 A;  1IK3 A;  3U6G A;  2KXT A;  1LNH A;  5FBB A;  2WXU A;  2WXT A;  2SBL A;  1AH7 A;  3BND A;  1OLP A;  5FBG A;  1F8N A;  1GPL A;  2LGE A;  1N8S A;  1LOX A;  1N8Q A;  2HUC A; 
#chains in the Genus database with same CATH homology
 4JDG A;  1GYG A;  1HU9 A;  1RRH A;  1ROV A;  4QWT A;  1LPA B;  2OXE A;  3FG3 A;  1RP1 A;  3V98 A;  1RRL A;  1YGE A;  3FG4 A;  1QMD A;  3O8Y A;  5FBA A;  2IUK A;  3BNC A;  2PPL A;  3VF1 A;  3BNB A;  1P6D A;  5EEO A;  1ETH A;  1HPL A;  3PZW A;  4WFO A;  4CXV A;  2FFZ A;  1LPB B;  1CA1 A;  2WY6 A;  1FGR A;  5FBF A;  3W52 A;  3V92 A;  4CXP A;  3CWZ B;  1FGO A;  2P0M A;  2FGN A;  5FBD A;  5FB9 A;  2PVS A;  5FBC A;  3FG1 A;  2FNQ A;  3V99 A;  1KHO A;  4CWM A;  1P6E A;  3SNG A;  1NO3 A;  1JNQ A;  4WHA A;  4DJ4 A;  1FGQ A;  1Y4K A;  1FGM A;  1AK0 A;  4CXO A;  1P5X A;  1W52 X;  1FGT A;  2IUJ A;  4NRE A;  3BNE A;  1QM6 A;  1BU8 A;  1IK3 A;  1LNH A;  5FBB A;  2WXU A;  2WXT A;  2SBL A;  1AH7 A;  3BND A;  1OLP A;  5FBG A;  1F8N A;  1GPL A;  1N8S A;  1LOX A;  1N8Q A;  2HUC A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...