1P6EA

Structure of the d55n mutant of phospholipase c from bacillus cereus in complex with 1,2-di-n-pentanoyl-sn-glycero-3-dithiophosphocholine
Total Genus 102
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
102
sequence length
245
structure length
245
Chain Sequence
WSAEDKHKEGVNSHLWIVNRAIDIMSRNTTLVKQDRVAQLNEWRTELENGIYAANYENPYYDNSTFASHFYDPDNGKTYIPFAKQAKETGAKYFKLAGESYKNKDMKQAFFYLGLSLHYLGDVNQPMHAANFTNLSYPQGFHSKYENFVDTIKDNYKVTDGNGYWNWKGTNPEEWIHGAAVVAKQDYSGIVNDNTKDWFVKAAVSQEYADKWRAEVTPMTGKRLMDAQRVTAGYIQLWFDTYGDR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Using X-ray crystallography of the Asp55Asn mutant of the phosphatidylcholine-preferring phospholipase C from Bacillus cereus to support the mechanistic role of Asp55 as the general base.
pubmed doi rcsb
molecule tags Hydrolase
source organism Bacillus cereus
molecule keywords Phospholipase C
total genus 102
structure length 245
sequence length 245
ec nomenclature ec 3.1.4.3: Phospholipase C.
pdb deposition date 2003-04-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00882 Zn_dep_PLPC Zinc dependent phospholipase C
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.575.10 Mainly Alpha Orthogonal Bundle P1 Nuclease P1 Nuclease 1p6eA00
4CXOA 2WY6A 2FFZA 5FBDA 1GYGA 5FBCA 2HUCA 4DJ4A 2WXTA 5FB9A 5FBGA 1P6DA 4CXPA 1AH7A 1QMDA 4JDGA 1KHOA 4CWMA 2WXUA 1OLPA 5FBBA 1P6EA 5FBFA 2FGNA 1QM6A 1P5XA 1CA1A 4CXVA 3W52A 5FBAA 1AK0A 3SNGA
chains in the Genus database with same CATH superfamily
4CXOA 2WY6A 2FFZA 5FBDA 1GYGA 5FBCA 2HUCA 4DJ4A 2WXTA 5FB9A 5FBGA 1P6DA 4CXPA 1AH7A 1QMDA 4JDGA 1KHOA 4CWMA 2WXUA 1OLPA 5FBBA 1P6EA 5FBFA 2FGNA 1QM6A 1P5XA 1CA1A 4CXVA 3W52A 5FBAA 1AK0A 3SNGA
chains in the Genus database with same CATH topology
4CXOA 2WY6A 2FFZA 5FBDA 1GYGA 5FBCA 2HUCA 4DJ4A 2WXTA 5FB9A 5FBGA 1P6DA 4CXPA 1AH7A 1QMDA 4JDGA 1KHOA 4CWMA 2WXUA 1OLPA 5FBBA 1P6EA 5FBFA 2FGNA 1QM6A 1P5XA 1CA1A 4CXVA 3W52A 5FBAA 1AK0A 3SNGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4CXO A;  2WY6 A;  2FFZ A;  5FBD A;  1GYG A;  5FBC A;  2HUC A;  4DJ4 A;  2WXT A;  5FB9 A;  5FBG A;  1P6D A;  4CXP A;  1AH7 A;  1QMD A;  4JDG A;  1KHO A;  4CWM A;  2WXU A;  1OLP A;  5FBB A;  1P6E A;  5FBF A;  2FGN A;  1QM6 A;  1P5X A;  1CA1 A;  4CXV A;  3W52 A;  5FBA A;  1AK0 A;  3SNG A; 
#chains in the Genus database with same CATH topology
 4CXO A;  2WY6 A;  2FFZ A;  5FBD A;  1GYG A;  5FBC A;  2HUC A;  4DJ4 A;  2WXT A;  5FB9 A;  5FBG A;  1P6D A;  4CXP A;  1AH7 A;  1QMD A;  4JDG A;  1KHO A;  4CWM A;  2WXU A;  1OLP A;  5FBB A;  1P6E A;  5FBF A;  2FGN A;  1QM6 A;  1P5X A;  1CA1 A;  4CXV A;  3W52 A;  5FBA A;  1AK0 A;  3SNG A; 
#chains in the Genus database with same CATH homology
 4CXO A;  2WY6 A;  2FFZ A;  5FBD A;  1GYG A;  5FBC A;  2HUC A;  4DJ4 A;  2WXT A;  5FB9 A;  5FBG A;  1P6D A;  4CXP A;  1AH7 A;  1QMD A;  4JDG A;  1KHO A;  4CWM A;  2WXU A;  1OLP A;  5FBB A;  1P6E A;  5FBF A;  2FGN A;  1QM6 A;  1P5X A;  1CA1 A;  4CXV A;  3W52 A;  5FBA A;  1AK0 A;  3SNG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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