1TB6L

2.5a crystal structure of the antithrombin-thrombin-heparin ternary complex
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
43
structure length
43
Chain Sequence
SEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of the antithrombin-thrombin-heparin ternary complex reveals the antithrombotic mechanism of heparin.
pubmed doi rcsb
molecule tags Hydrolase/blood clotting
source organism Homo sapiens
molecule keywords thrombin
total genus 3
structure length 43
sequence length 43
ec nomenclature ec 3.4.21.5: Thrombin.
pdb deposition date 2004-05-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF09396 Thrombin_light Thrombin light chain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.140.10 Few Secondary Structures Irregular Epsilon-Thrombin; Chain L Thrombin light chain domain 1tb6L00
1AVGL 1JMOL 3EDXA 1A0HA 3HKIA 4DY7A 3BEIA 3HK6A 1TBQJ 1TQ7A 3GISA 3E6PL 1JOUA 3BEFA 1TBRJ 3B9FL 2PV9A 4RKOA 1TB6L 3LU9A 2PUXA 1Z8JA 2A1DA 2ODYA 2PGQA 2B5TA
chains in the Genus database with same CATH superfamily
1AVGL 1JMOL 3EDXA 1A0HA 3HKIA 4DY7A 3BEIA 3HK6A 1TBQJ 1TQ7A 3GISA 3E6PL 1JOUA 3BEFA 1TBRJ 3B9FL 2PV9A 4RKOA 1TB6L 3LU9A 2PUXA 1Z8JA 2A1DA 2ODYA 2PGQA 2B5TA
chains in the Genus database with same CATH topology
1AVGL 1JMOL 3EDXA 1A0HA 3HKIA 4DY7A 3BEIA 3HK6A 1TBQJ 1TQ7A 3GISA 3E6PL 1JOUA 3BEFA 1TBRJ 3B9FL 2PV9A 4RKOA 1TB6L 3LU9A 2PUXA 1Z8JA 2A1DA 2ODYA 2PGQA 2B5TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AVG L;  1JMO L;  3EDX A;  1A0H A;  3HKI A;  4DY7 A;  3BEI A;  3HK6 A;  1TBQ J;  1TQ7 A;  3GIS A;  3E6P L;  1JOU A;  3BEF A;  1TBR J;  3B9F L;  2PV9 A;  4RKO A;  1TB6 L;  3LU9 A;  2PUX A;  1Z8J A;  2A1D A;  2ODY A;  2PGQ A;  2B5T A; 
#chains in the Genus database with same CATH topology
 1AVG L;  1JMO L;  3EDX A;  1A0H A;  3HKI A;  4DY7 A;  3BEI A;  3HK6 A;  1TBQ J;  1TQ7 A;  3GIS A;  3E6P L;  1JOU A;  3BEF A;  1TBR J;  3B9F L;  2PV9 A;  4RKO A;  1TB6 L;  3LU9 A;  2PUX A;  1Z8J A;  2A1D A;  2ODY A;  2PGQ A;  2B5T A; 
#chains in the Genus database with same CATH homology
 1AVG L;  1JMO L;  3EDX A;  1A0H A;  3HKI A;  4DY7 A;  3BEI A;  3HK6 A;  1TBQ J;  1TQ7 A;  3GIS A;  3E6P L;  1JOU A;  3BEF A;  1TBR J;  3B9F L;  2PV9 A;  4RKO A;  1TB6 L;  3LU9 A;  2PUX A;  1Z8J A;  2A1D A;  2ODY A;  2PGQ A;  2B5T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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