3EDXA

Crystal structure of the w215a/e217a mutant of murine thrombin
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
42
structure length
42
Chain Sequence
FHTFFNEKTFGLGEADCGLRPLFEKKSLKDTTEKELLDSYID
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase
molecule keywords Thrombin light chain
publication title Molecular Basis for the Kinetic Differences of the W215A/E217A Mutant of Human and Murine Thrombin
rcsb
source organism Mus musculus
total genus 3
structure length 42
sequence length 42
chains with identical sequence C, E
ec nomenclature ec 3.4.21.5: Thrombin.
pdb deposition date 2008-09-03
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.140.10 Few Secondary Structures Irregular Epsilon-Thrombin; Chain L Thrombin light chain domain 3edxA00
2PGQA 2PUXA 1TQ7A 1JMOL 3E6PL 2A1DA 4RKOA 1A0HA 2PV9A 1TBQJ 3GISA 1TB6L 3BEIA 3EDXA 1AVGL 1TBRJ 1JOUA 4DY7A 2B5TA 1Z8JA 3HKIA 3B9FL 2ODYA 3LU9A 3HK6A 3BEFA
chains in the Genus database with same CATH superfamily
2PGQA 2PUXA 1TQ7A 1JMOL 3E6PL 2A1DA 4RKOA 1A0HA 2PV9A 1TBQJ 3GISA 1TB6L 3BEIA 3EDXA 1AVGL 1TBRJ 1JOUA 4DY7A 2B5TA 1Z8JA 3HKIA 3B9FL 2ODYA 3LU9A 3HK6A 3BEFA
chains in the Genus database with same CATH topology
2PGQA 2PUXA 1TQ7A 1JMOL 3E6PL 2A1DA 4RKOA 1A0HA 2PV9A 1TBQJ 3GISA 1TB6L 3BEIA 3EDXA 1AVGL 1TBRJ 1JOUA 4DY7A 2B5TA 1Z8JA 3HKIA 3B9FL 2ODYA 3LU9A 3HK6A 3BEFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PGQ A;  2PUX A;  1TQ7 A;  1JMO L;  3E6P L;  2A1D A;  4RKO A;  1A0H A;  2PV9 A;  1TBQ J;  3GIS A;  1TB6 L;  3BEI A;  3EDX A;  1AVG L;  1TBR J;  1JOU A;  4DY7 A;  2B5T A;  1Z8J A;  3HKI A;  3B9F L;  2ODY A;  3LU9 A;  3HK6 A;  3BEF A; 
#chains in the Genus database with same CATH topology
 2PGQ A;  2PUX A;  1TQ7 A;  1JMO L;  3E6P L;  2A1D A;  4RKO A;  1A0H A;  2PV9 A;  1TBQ J;  3GIS A;  1TB6 L;  3BEI A;  3EDX A;  1AVG L;  1TBR J;  1JOU A;  4DY7 A;  2B5T A;  1Z8J A;  3HKI A;  3B9F L;  2ODY A;  3LU9 A;  3HK6 A;  3BEF A; 
#chains in the Genus database with same CATH homology
 2PGQ A;  2PUX A;  1TQ7 A;  1JMO L;  3E6P L;  2A1D A;  4RKO A;  1A0H A;  2PV9 A;  1TBQ J;  3GIS A;  1TB6 L;  3BEI A;  3EDX A;  1AVG L;  1TBR J;  1JOU A;  4DY7 A;  2B5T A;  1Z8J A;  3HKI A;  3B9F L;  2ODY A;  3LU9 A;  3HK6 A;  3BEF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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