1Z8JA

Crystal structure of the thrombin mutant g193p bound to ppack
Total Genus 1
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
40
structure length
40
Chain Sequence
TFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYID
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Energetic and structural consequences of perturbing Gly-193 in the oxyanion hole of serine proteases
pubmed doi rcsb
molecule keywords Thrombin light chain
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
total genus 1
structure length 40
sequence length 40
ec nomenclature ec 3.4.21.5: Thrombin.
pdb deposition date 2005-03-30
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.140.10 Few Secondary Structures Irregular Epsilon-Thrombin; Chain L Thrombin light chain domain 1z8jA00
2PV9A 1JOUA 3LU9A 4DY7A 4RKOA 3HK6A 2A1DA 3HKIA 1A0HA 2B5TA 2PUXA 1TB6L 3GISA 3E6PL 1AVGL 1TQ7A 1TBRJ 1TBQJ 3BEFA 1Z8JA 3EDXA 2ODYA 1JMOL 3B9FL 2PGQA 3BEIA
chains in the Genus database with same CATH superfamily
2PV9A 1JOUA 3LU9A 4DY7A 4RKOA 3HK6A 2A1DA 3HKIA 1A0HA 2B5TA 2PUXA 1TB6L 3GISA 3E6PL 1AVGL 1TQ7A 1TBRJ 1TBQJ 3BEFA 1Z8JA 3EDXA 2ODYA 1JMOL 3B9FL 2PGQA 3BEIA
chains in the Genus database with same CATH topology
2PV9A 1JOUA 3LU9A 4DY7A 4RKOA 3HK6A 2A1DA 3HKIA 1A0HA 2B5TA 2PUXA 1TB6L 3GISA 3E6PL 1AVGL 1TQ7A 1TBRJ 1TBQJ 3BEFA 1Z8JA 3EDXA 2ODYA 1JMOL 3B9FL 2PGQA 3BEIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PV9 A;  1JOU A;  3LU9 A;  4DY7 A;  4RKO A;  3HK6 A;  2A1D A;  3HKI A;  1A0H A;  2B5T A;  2PUX A;  1TB6 L;  3GIS A;  3E6P L;  1AVG L;  1TQ7 A;  1TBR J;  1TBQ J;  3BEF A;  1Z8J A;  3EDX A;  2ODY A;  1JMO L;  3B9F L;  2PGQ A;  3BEI A; 
#chains in the Genus database with same CATH topology
 2PV9 A;  1JOU A;  3LU9 A;  4DY7 A;  4RKO A;  3HK6 A;  2A1D A;  3HKI A;  1A0H A;  2B5T A;  2PUX A;  1TB6 L;  3GIS A;  3E6P L;  1AVG L;  1TQ7 A;  1TBR J;  1TBQ J;  3BEF A;  1Z8J A;  3EDX A;  2ODY A;  1JMO L;  3B9F L;  2PGQ A;  3BEI A; 
#chains in the Genus database with same CATH homology
 2PV9 A;  1JOU A;  3LU9 A;  4DY7 A;  4RKO A;  3HK6 A;  2A1D A;  3HKI A;  1A0H A;  2B5T A;  2PUX A;  1TB6 L;  3GIS A;  3E6P L;  1AVG L;  1TQ7 A;  1TBR J;  1TBQ J;  3BEF A;  1Z8J A;  3EDX A;  2ODY A;  1JMO L;  3B9F L;  2PGQ A;  3BEI A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...