1Z8JA

Crystal structure of the thrombin mutant g193p bound to ppack
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
40
structure length
40
Chain Sequence
TFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYID
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase/hydrolase inhibitor
molecule keywords Thrombin light chain
publication title Energetic and structural consequences of perturbing Gly-193 in the oxyanion hole of serine proteases
pubmed doi rcsb
source organism Homo sapiens
total genus 1
structure length 40
sequence length 40
ec nomenclature ec 3.4.21.5: Thrombin.
pdb deposition date 2005-03-30
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.140.10 Few Secondary Structures Irregular Epsilon-Thrombin; Chain L Thrombin light chain domain 1z8jA00
3LU9A 3BEFA 2PGQA 3GISA 4DY7A 2B5TA 3E6PL 1Z8JA 3BEIA 4RKOA 1AVGL 2ODYA 1TBRJ 1JOUA 1TB6L 1TQ7A 2PV9A 3HK6A 3B9FL 3HKIA 3EDXA 1TBQJ 1JMOL 2A1DA 1A0HA 2PUXA
chains in the Genus database with same CATH superfamily
3LU9A 3BEFA 2PGQA 3GISA 4DY7A 2B5TA 3E6PL 1Z8JA 3BEIA 4RKOA 1AVGL 2ODYA 1TBRJ 1JOUA 1TB6L 1TQ7A 2PV9A 3HK6A 3B9FL 3HKIA 3EDXA 1TBQJ 1JMOL 2A1DA 1A0HA 2PUXA
chains in the Genus database with same CATH topology
3LU9A 3BEFA 2PGQA 3GISA 4DY7A 2B5TA 3E6PL 1Z8JA 3BEIA 4RKOA 1AVGL 2ODYA 1TBRJ 1JOUA 1TB6L 1TQ7A 2PV9A 3HK6A 3B9FL 3HKIA 3EDXA 1TBQJ 1JMOL 2A1DA 1A0HA 2PUXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LU9 A;  3BEF A;  2PGQ A;  3GIS A;  4DY7 A;  2B5T A;  3E6P L;  1Z8J A;  3BEI A;  4RKO A;  1AVG L;  2ODY A;  1TBR J;  1JOU A;  1TB6 L;  1TQ7 A;  2PV9 A;  3HK6 A;  3B9F L;  3HKI A;  3EDX A;  1TBQ J;  1JMO L;  2A1D A;  1A0H A;  2PUX A; 
#chains in the Genus database with same CATH topology
 3LU9 A;  3BEF A;  2PGQ A;  3GIS A;  4DY7 A;  2B5T A;  3E6P L;  1Z8J A;  3BEI A;  4RKO A;  1AVG L;  2ODY A;  1TBR J;  1JOU A;  1TB6 L;  1TQ7 A;  2PV9 A;  3HK6 A;  3B9F L;  3HKI A;  3EDX A;  1TBQ J;  1JMO L;  2A1D A;  1A0H A;  2PUX A; 
#chains in the Genus database with same CATH homology
 3LU9 A;  3BEF A;  2PGQ A;  3GIS A;  4DY7 A;  2B5T A;  3E6P L;  1Z8J A;  3BEI A;  4RKO A;  1AVG L;  2ODY A;  1TBR J;  1JOU A;  1TB6 L;  1TQ7 A;  2PV9 A;  3HK6 A;  3B9F L;  3HKI A;  3EDX A;  1TBQ J;  1JMO L;  2A1D A;  1A0H A;  2PUX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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