3LU9A

Crystal structure of human thrombin mutant s195a in complex with the extracellular fragment of human par1
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
44
structure length
44
Chain Sequence
SEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYID
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase
molecule keywords Prothrombin
publication title Crystal structure of thrombin bound to the uncleaved extracellular fragment of PAR1.
pubmed doi rcsb
source organism Homo sapiens
total genus 3
structure length 44
sequence length 44
chains with identical sequence D
ec nomenclature ec 3.4.21.5: Thrombin.
pdb deposition date 2010-02-17
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.140.10 Few Secondary Structures Irregular Epsilon-Thrombin; Chain L Thrombin light chain domain 3lu9A00
2PV9A 1A0HA 1TQ7A 3LU9A 2ODYA 1AVGL 3EDXA 2B5TA 3B9FL 1JOUA 4RKOA 4DY7A 3BEFA 2PGQA 1JMOL 1TB6L 1TBRJ 3HK6A 3GISA 1Z8JA 2A1DA 3BEIA 1TBQJ 2PUXA 3E6PL 3HKIA
chains in the Genus database with same CATH superfamily
2PV9A 1A0HA 1TQ7A 3LU9A 2ODYA 1AVGL 3EDXA 2B5TA 3B9FL 1JOUA 4RKOA 4DY7A 3BEFA 2PGQA 1JMOL 1TB6L 1TBRJ 3HK6A 3GISA 1Z8JA 2A1DA 3BEIA 1TBQJ 2PUXA 3E6PL 3HKIA
chains in the Genus database with same CATH topology
2PV9A 1A0HA 1TQ7A 3LU9A 2ODYA 1AVGL 3EDXA 2B5TA 3B9FL 1JOUA 4RKOA 4DY7A 3BEFA 2PGQA 1JMOL 1TB6L 1TBRJ 3HK6A 3GISA 1Z8JA 2A1DA 3BEIA 1TBQJ 2PUXA 3E6PL 3HKIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PV9 A;  1A0H A;  1TQ7 A;  3LU9 A;  2ODY A;  1AVG L;  3EDX A;  2B5T A;  3B9F L;  1JOU A;  4RKO A;  4DY7 A;  3BEF A;  2PGQ A;  1JMO L;  1TB6 L;  1TBR J;  3HK6 A;  3GIS A;  1Z8J A;  2A1D A;  3BEI A;  1TBQ J;  2PUX A;  3E6P L;  3HKI A; 
#chains in the Genus database with same CATH topology
 2PV9 A;  1A0H A;  1TQ7 A;  3LU9 A;  2ODY A;  1AVG L;  3EDX A;  2B5T A;  3B9F L;  1JOU A;  4RKO A;  4DY7 A;  3BEF A;  2PGQ A;  1JMO L;  1TB6 L;  1TBR J;  3HK6 A;  3GIS A;  1Z8J A;  2A1D A;  3BEI A;  1TBQ J;  2PUX A;  3E6P L;  3HKI A; 
#chains in the Genus database with same CATH homology
 2PV9 A;  1A0H A;  1TQ7 A;  3LU9 A;  2ODY A;  1AVG L;  3EDX A;  2B5T A;  3B9F L;  1JOU A;  4RKO A;  4DY7 A;  3BEF A;  2PGQ A;  1JMO L;  1TB6 L;  1TBR J;  3HK6 A;  3GIS A;  1Z8J A;  2A1D A;  3BEI A;  1TBQ J;  2PUX A;  3E6P L;  3HKI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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