2PHEA

Model for vp16 binding to pc4
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
66
structure length
66
Chain Sequence
AMFQIGKMRYVSVRDFKGKVLIDIREYWMDPEGEMKPGRKGISLNPEQWSQLKEQISDIDDAVRKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Properties of the Promiscuous VP16 Activation Domain
pubmed doi rcsb
molecule keywords TRANSCRIPTIONAL COACTIVATOR PC4
molecule tags Transcription
source organism Homo sapiens
total genus 14
structure length 66
sequence length 66
chains with identical sequence B
ec nomenclature
pdb deposition date 2007-04-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02229 PC4 Transcriptional Coactivator p15 (PC4)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.31.10 Mainly Beta Roll Transcriptional Co-activator pc4; Chain A Transcriptional Coactivator Pc4; Chain A 2pheA00
4AGHA 1PCFA 4KOQA 4BG7A 3R9YA 2IT9A 4KOPA 3N1HA 2NVNA 2C62A 3RA0A 4USGA 3N1KA 4BHMA 1L3AA 2PHEA 3N1IA 4KOOA 3N1LA 3N1JA 3R9ZA
chains in the Genus database with same CATH superfamily
4AGHA 1PCFA 4KOQA 2GIDA 3K44A 4BG7A 2GIAB 3R9YA 2IT9A 4KOPA 4BOBA 3N1HA 2GJEA 4J38A 3CM1A 2NVNA 2C62A 2GIAA 5FGPA 2GJED 4BODA 4USGA 3RA0A 2M4FA 3N1KA 4BHMA 1L3AA 4BXMA 2PHEA 4BF3A 3N1IA 4KOOA 2GIDB 3OBHA 3N1LA 3N1JA 3R9ZA 3MTVA
chains in the Genus database with same CATH topology
4AGHA 1PCFA 4KOQA 4BG7A 3R9YA 2IT9A 4KOPA 3N1HA 2NVNA 2C62A 3RA0A 4USGA 3N1KA 4BHMA 1L3AA 2PHEA 3N1IA 4KOOA 3N1LA 3N1JA 3R9ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4AGH A;  1PCF A;  4KOQ A;  4BG7 A;  3R9Y A;  2IT9 A;  4KOP A;  3N1H A;  2NVN A;  2C62 A;  3RA0 A;  4USG A;  3N1K A;  4BHM A;  1L3A A;  2PHE A;  3N1I A;  4KOO A;  3N1L A;  3N1J A;  3R9Z A; 
#chains in the Genus database with same CATH topology
 4AGH A;  1PCF A;  4KOQ A;  2GID A;  3K44 A;  4BG7 A;  2GIA B;  3R9Y A;  2IT9 A;  4KOP A;  4BOB A;  3N1H A;  2GJE A;  4J38 A;  3CM1 A;  2NVN A;  2C62 A;  2GIA A;  5FGP A;  2GJE D;  4BOD A;  4USG A;  3RA0 A;  2M4F A;  3N1K A;  4BHM A;  1L3A A;  4BXM A;  2PHE A;  4BF3 A;  3N1I A;  4KOO A;  2GID B;  3OBH A;  3N1L A;  3N1J A;  3R9Z A;  3MTV A; 
#chains in the Genus database with same CATH homology
 4AGH A;  1PCF A;  4KOQ A;  4BG7 A;  3R9Y A;  2IT9 A;  4KOP A;  3N1H A;  2NVN A;  2C62 A;  3RA0 A;  4USG A;  3N1K A;  4BHM A;  1L3A A;  2PHE A;  3N1I A;  4KOO A;  3N1L A;  3N1J A;  3R9Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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