2ODYA

Thrombin-bound boophilin displays a functional and accessible reactive-site loop
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
44
structure length
44
Chain Sequence
FQPFFNEKTFGAGEADCGLRPLFEKKQVQDQTEKELFESYIEGR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Isolation, cloning and structural characterisation of boophilin, a multifunctional kunitz-type proteinase inhibitor from the cattle tick.
pubmed doi rcsb
molecule tags Blood clotting/blood clotting inhibitor
source organism Rhipicephalus microplus
molecule keywords Prothrombin (EC 3.4.21.5)
total genus 3
structure length 44
sequence length 44
chains with identical sequence C
ec nomenclature ec 3.4.21.5: Thrombin.
pdb deposition date 2006-12-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09396 Thrombin_light Thrombin light chain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.140.10 Few Secondary Structures Irregular Epsilon-Thrombin; Chain L Thrombin light chain domain 2odyA00
3BEIA 4RKOA 1Z8JA 1TBRJ 3EDXA 2ODYA 1TB6L 3BEFA 2PGQA 2PV9A 1JMOL 3HK6A 1TBQJ 3B9FL 1A0HA 2A1DA 4DY7A 3LU9A 3HKIA 1AVGL 1JOUA 1TQ7A 2B5TA 3GISA 2PUXA 3E6PL
chains in the Genus database with same CATH superfamily
3BEIA 4RKOA 1Z8JA 1TBRJ 3EDXA 2ODYA 1TB6L 3BEFA 2PGQA 2PV9A 1JMOL 3HK6A 1TBQJ 3B9FL 1A0HA 2A1DA 4DY7A 3LU9A 3HKIA 1AVGL 1JOUA 1TQ7A 2B5TA 3GISA 2PUXA 3E6PL
chains in the Genus database with same CATH topology
3BEIA 4RKOA 1Z8JA 1TBRJ 3EDXA 2ODYA 1TB6L 3BEFA 2PGQA 2PV9A 1JMOL 3HK6A 1TBQJ 3B9FL 1A0HA 2A1DA 4DY7A 3LU9A 3HKIA 1AVGL 1JOUA 1TQ7A 2B5TA 3GISA 2PUXA 3E6PL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BEI A;  4RKO A;  1Z8J A;  1TBR J;  3EDX A;  2ODY A;  1TB6 L;  3BEF A;  2PGQ A;  2PV9 A;  1JMO L;  3HK6 A;  1TBQ J;  3B9F L;  1A0H A;  2A1D A;  4DY7 A;  3LU9 A;  3HKI A;  1AVG L;  1JOU A;  1TQ7 A;  2B5T A;  3GIS A;  2PUX A;  3E6P L; 
#chains in the Genus database with same CATH topology
 3BEI A;  4RKO A;  1Z8J A;  1TBR J;  3EDX A;  2ODY A;  1TB6 L;  3BEF A;  2PGQ A;  2PV9 A;  1JMO L;  3HK6 A;  1TBQ J;  3B9F L;  1A0H A;  2A1D A;  4DY7 A;  3LU9 A;  3HKI A;  1AVG L;  1JOU A;  1TQ7 A;  2B5T A;  3GIS A;  2PUX A;  3E6P L; 
#chains in the Genus database with same CATH homology
 3BEI A;  4RKO A;  1Z8J A;  1TBR J;  3EDX A;  2ODY A;  1TB6 L;  3BEF A;  2PGQ A;  2PV9 A;  1JMO L;  3HK6 A;  1TBQ J;  3B9F L;  1A0H A;  2A1D A;  4DY7 A;  3LU9 A;  3HKI A;  1AVG L;  1JOU A;  1TQ7 A;  2B5T A;  3GIS A;  2PUX A;  3E6P L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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