2PV9A

Crystal structure of murine thrombin in complex with the extracellular fragment of murine par4
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
43
structure length
43
Chain Sequence
FHTFFNEKTFGLGEADCGLRPLFEKKSLKDTTEKELLDSYIDG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structures of murine thrombin in complex with the extracellular fragments of murine protease-activated receptors PAR3 and PAR4.
pubmed doi rcsb
molecule keywords Thrombin light chain
molecule tags Hydrolase
source organism Mus musculus
total genus 3
structure length 43
sequence length 43
ec nomenclature ec 3.4.21.5: Thrombin.
pdb deposition date 2007-05-09
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.140.10 Few Secondary Structures Irregular Epsilon-Thrombin; Chain L Thrombin light chain domain 2pv9A00
3HKIA 2ODYA 1AVGL 4RKOA 2PGQA 3LU9A 1TBQJ 2A1DA 3HK6A 3BEIA 3E6PL 3B9FL 2B5TA 1JOUA 3EDXA 3BEFA 1TQ7A 3GISA 1Z8JA 4DY7A 1A0HA 2PV9A 1TBRJ 1TB6L 1JMOL 2PUXA
chains in the Genus database with same CATH superfamily
3HKIA 2ODYA 1AVGL 4RKOA 2PGQA 3LU9A 1TBQJ 2A1DA 3HK6A 3BEIA 3E6PL 3B9FL 2B5TA 1JOUA 3EDXA 3BEFA 1TQ7A 3GISA 1Z8JA 4DY7A 1A0HA 2PV9A 1TBRJ 1TB6L 1JMOL 2PUXA
chains in the Genus database with same CATH topology
3HKIA 2ODYA 1AVGL 4RKOA 2PGQA 3LU9A 1TBQJ 2A1DA 3HK6A 3BEIA 3E6PL 3B9FL 2B5TA 1JOUA 3EDXA 3BEFA 1TQ7A 3GISA 1Z8JA 4DY7A 1A0HA 2PV9A 1TBRJ 1TB6L 1JMOL 2PUXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HKI A;  2ODY A;  1AVG L;  4RKO A;  2PGQ A;  3LU9 A;  1TBQ J;  2A1D A;  3HK6 A;  3BEI A;  3E6P L;  3B9F L;  2B5T A;  1JOU A;  3EDX A;  3BEF A;  1TQ7 A;  3GIS A;  1Z8J A;  4DY7 A;  1A0H A;  2PV9 A;  1TBR J;  1TB6 L;  1JMO L;  2PUX A; 
#chains in the Genus database with same CATH topology
 3HKI A;  2ODY A;  1AVG L;  4RKO A;  2PGQ A;  3LU9 A;  1TBQ J;  2A1D A;  3HK6 A;  3BEI A;  3E6P L;  3B9F L;  2B5T A;  1JOU A;  3EDX A;  3BEF A;  1TQ7 A;  3GIS A;  1Z8J A;  4DY7 A;  1A0H A;  2PV9 A;  1TBR J;  1TB6 L;  1JMO L;  2PUX A; 
#chains in the Genus database with same CATH homology
 3HKI A;  2ODY A;  1AVG L;  4RKO A;  2PGQ A;  3LU9 A;  1TBQ J;  2A1D A;  3HK6 A;  3BEI A;  3E6P L;  3B9F L;  2B5T A;  1JOU A;  3EDX A;  3BEF A;  1TQ7 A;  3GIS A;  1Z8J A;  4DY7 A;  1A0H A;  2PV9 A;  1TBR J;  1TB6 L;  1JMO L;  2PUX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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