3BEFA

Crystal structure of thrombin bound to the extracellular fragment of par1
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
44
structure length
44
Chain Sequence
SEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYID
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural identification of the pathway of long-range communication in an allosteric enzyme.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Prothrombin
total genus 3
structure length 44
sequence length 44
chains with identical sequence D
ec nomenclature ec 3.4.21.5: Thrombin.
pdb deposition date 2007-11-17
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.140.10 Few Secondary Structures Irregular Epsilon-Thrombin; Chain L Thrombin light chain domain 3befA00
1TBQJ 2B5TA 3LU9A 3B9FL 1TB6L 1JMOL 1A0HA 3BEFA 4RKOA 3EDXA 3GISA 4DY7A 2PV9A 2A1DA 1TQ7A 3BEIA 2ODYA 2PGQA 2PUXA 1TBRJ 3HK6A 3E6PL 1JOUA 3HKIA 1AVGL 1Z8JA
chains in the Genus database with same CATH superfamily
1TBQJ 2B5TA 3LU9A 3B9FL 1TB6L 1JMOL 1A0HA 3BEFA 4RKOA 3EDXA 3GISA 4DY7A 2PV9A 2A1DA 1TQ7A 3BEIA 2ODYA 2PGQA 2PUXA 1TBRJ 3HK6A 3E6PL 1JOUA 3HKIA 1AVGL 1Z8JA
chains in the Genus database with same CATH topology
1TBQJ 2B5TA 3LU9A 3B9FL 1TB6L 1JMOL 1A0HA 3BEFA 4RKOA 3EDXA 3GISA 4DY7A 2PV9A 2A1DA 1TQ7A 3BEIA 2ODYA 2PGQA 2PUXA 1TBRJ 3HK6A 3E6PL 1JOUA 3HKIA 1AVGL 1Z8JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TBQ J;  2B5T A;  3LU9 A;  3B9F L;  1TB6 L;  1JMO L;  1A0H A;  3BEF A;  4RKO A;  3EDX A;  3GIS A;  4DY7 A;  2PV9 A;  2A1D A;  1TQ7 A;  3BEI A;  2ODY A;  2PGQ A;  2PUX A;  1TBR J;  3HK6 A;  3E6P L;  1JOU A;  3HKI A;  1AVG L;  1Z8J A; 
#chains in the Genus database with same CATH topology
 1TBQ J;  2B5T A;  3LU9 A;  3B9F L;  1TB6 L;  1JMO L;  1A0H A;  3BEF A;  4RKO A;  3EDX A;  3GIS A;  4DY7 A;  2PV9 A;  2A1D A;  1TQ7 A;  3BEI A;  2ODY A;  2PGQ A;  2PUX A;  1TBR J;  3HK6 A;  3E6P L;  1JOU A;  3HKI A;  1AVG L;  1Z8J A; 
#chains in the Genus database with same CATH homology
 1TBQ J;  2B5T A;  3LU9 A;  3B9F L;  1TB6 L;  1JMO L;  1A0H A;  3BEF A;  4RKO A;  3EDX A;  3GIS A;  4DY7 A;  2PV9 A;  2A1D A;  1TQ7 A;  3BEI A;  2ODY A;  2PGQ A;  2PUX A;  1TBR J;  3HK6 A;  3E6P L;  1JOU A;  3HKI A;  1AVG L;  1Z8J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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