3BEIA

Crystal structure of the slow form of thrombin in a self_inhibited conformation
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
41
structure length
41
Chain Sequence
YQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural identification of the pathway of long-range communication in an allosteric enzyme.
pubmed doi rcsb
molecule keywords Prothrombin
molecule tags Hydrolase
source organism Homo sapiens
total genus 3
structure length 41
sequence length 41
ec nomenclature ec 3.4.21.5: Thrombin.
pdb deposition date 2007-11-19
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.140.10 Few Secondary Structures Irregular Epsilon-Thrombin; Chain L Thrombin light chain domain 3beiA00
1TB6L 3EDXA 3E6PL 1A0HA 2ODYA 4RKOA 3B9FL 1JOUA 3HKIA 1TBQJ 3BEIA 3LU9A 1TBRJ 2PGQA 1TQ7A 1Z8JA 3BEFA 2PUXA 1AVGL 2A1DA 1JMOL 2B5TA 2PV9A 4DY7A 3HK6A 3GISA
chains in the Genus database with same CATH superfamily
1TB6L 3EDXA 3E6PL 1A0HA 2ODYA 4RKOA 3B9FL 1JOUA 3HKIA 1TBQJ 3BEIA 3LU9A 1TBRJ 2PGQA 1TQ7A 1Z8JA 3BEFA 2PUXA 1AVGL 2A1DA 1JMOL 2B5TA 2PV9A 4DY7A 3HK6A 3GISA
chains in the Genus database with same CATH topology
1TB6L 3EDXA 3E6PL 1A0HA 2ODYA 4RKOA 3B9FL 1JOUA 3HKIA 1TBQJ 3BEIA 3LU9A 1TBRJ 2PGQA 1TQ7A 1Z8JA 3BEFA 2PUXA 1AVGL 2A1DA 1JMOL 2B5TA 2PV9A 4DY7A 3HK6A 3GISA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TB6 L;  3EDX A;  3E6P L;  1A0H A;  2ODY A;  4RKO A;  3B9F L;  1JOU A;  3HKI A;  1TBQ J;  3BEI A;  3LU9 A;  1TBR J;  2PGQ A;  1TQ7 A;  1Z8J A;  3BEF A;  2PUX A;  1AVG L;  2A1D A;  1JMO L;  2B5T A;  2PV9 A;  4DY7 A;  3HK6 A;  3GIS A; 
#chains in the Genus database with same CATH topology
 1TB6 L;  3EDX A;  3E6P L;  1A0H A;  2ODY A;  4RKO A;  3B9F L;  1JOU A;  3HKI A;  1TBQ J;  3BEI A;  3LU9 A;  1TBR J;  2PGQ A;  1TQ7 A;  1Z8J A;  3BEF A;  2PUX A;  1AVG L;  2A1D A;  1JMO L;  2B5T A;  2PV9 A;  4DY7 A;  3HK6 A;  3GIS A; 
#chains in the Genus database with same CATH homology
 1TB6 L;  3EDX A;  3E6P L;  1A0H A;  2ODY A;  4RKO A;  3B9F L;  1JOU A;  3HKI A;  1TBQ J;  3BEI A;  3LU9 A;  1TBR J;  2PGQ A;  1TQ7 A;  1Z8J A;  3BEF A;  2PUX A;  1AVG L;  2A1D A;  1JMO L;  2B5T A;  2PV9 A;  4DY7 A;  3HK6 A;  3GIS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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