3EDXA

Crystal structure of the w215a/e217a mutant of murine thrombin
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
42
structure length
42
Chain Sequence
FHTFFNEKTFGLGEADCGLRPLFEKKSLKDTTEKELLDSYID
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Molecular Basis for the Kinetic Differences of the W215A/E217A Mutant of Human and Murine Thrombin
rcsb
molecule tags Hydrolase
source organism Mus musculus
molecule keywords Thrombin light chain
total genus 3
structure length 42
sequence length 42
chains with identical sequence C, E
ec nomenclature ec 3.4.21.5: Thrombin.
pdb deposition date 2008-09-03
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.140.10 Few Secondary Structures Irregular Epsilon-Thrombin; Chain L Thrombin light chain domain 3edxA00
4DY7A 2PGQA 2PUXA 4RKOA 1JOUA 3HK6A 1TBQJ 3BEIA 2B5TA 3GISA 2PV9A 3E6PL 1JMOL 2A1DA 1TB6L 2ODYA 3HKIA 1TBRJ 1Z8JA 1TQ7A 3B9FL 1AVGL 3EDXA 3LU9A 1A0HA 3BEFA
chains in the Genus database with same CATH superfamily
4DY7A 2PGQA 2PUXA 4RKOA 1JOUA 3HK6A 1TBQJ 3BEIA 2B5TA 3GISA 2PV9A 3E6PL 1JMOL 2A1DA 1TB6L 2ODYA 3HKIA 1TBRJ 1Z8JA 1TQ7A 3B9FL 1AVGL 3EDXA 3LU9A 1A0HA 3BEFA
chains in the Genus database with same CATH topology
4DY7A 2PGQA 2PUXA 4RKOA 1JOUA 3HK6A 1TBQJ 3BEIA 2B5TA 3GISA 2PV9A 3E6PL 1JMOL 2A1DA 1TB6L 2ODYA 3HKIA 1TBRJ 1Z8JA 1TQ7A 3B9FL 1AVGL 3EDXA 3LU9A 1A0HA 3BEFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DY7 A;  2PGQ A;  2PUX A;  4RKO A;  1JOU A;  3HK6 A;  1TBQ J;  3BEI A;  2B5T A;  3GIS A;  2PV9 A;  3E6P L;  1JMO L;  2A1D A;  1TB6 L;  2ODY A;  3HKI A;  1TBR J;  1Z8J A;  1TQ7 A;  3B9F L;  1AVG L;  3EDX A;  3LU9 A;  1A0H A;  3BEF A; 
#chains in the Genus database with same CATH topology
 4DY7 A;  2PGQ A;  2PUX A;  4RKO A;  1JOU A;  3HK6 A;  1TBQ J;  3BEI A;  2B5T A;  3GIS A;  2PV9 A;  3E6P L;  1JMO L;  2A1D A;  1TB6 L;  2ODY A;  3HKI A;  1TBR J;  1Z8J A;  1TQ7 A;  3B9F L;  1AVG L;  3EDX A;  3LU9 A;  1A0H A;  3BEF A; 
#chains in the Genus database with same CATH homology
 4DY7 A;  2PGQ A;  2PUX A;  4RKO A;  1JOU A;  3HK6 A;  1TBQ J;  3BEI A;  2B5T A;  3GIS A;  2PV9 A;  3E6P L;  1JMO L;  2A1D A;  1TB6 L;  2ODY A;  3HKI A;  1TBR J;  1Z8J A;  1TQ7 A;  3B9F L;  1AVG L;  3EDX A;  3LU9 A;  1A0H A;  3BEF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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