3EDXA

Crystal structure of the w215a/e217a mutant of murine thrombin
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
42
structure length
42
Chain Sequence
FHTFFNEKTFGLGEADCGLRPLFEKKSLKDTTEKELLDSYID
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Molecular Basis for the Kinetic Differences of the W215A/E217A Mutant of Human and Murine Thrombin
rcsb
molecule keywords Thrombin light chain
molecule tags Hydrolase
source organism Mus musculus
total genus 3
structure length 42
sequence length 42
chains with identical sequence C, E
ec nomenclature ec 3.4.21.5: Thrombin.
pdb deposition date 2008-09-03
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.140.10 Few Secondary Structures Irregular Epsilon-Thrombin; Chain L Thrombin light chain domain 3edxA00
1A0HA 2B5TA 2ODYA 3BEFA 1TBRJ 3BEIA 4DY7A 1AVGL 2PGQA 2A1DA 1Z8JA 2PUXA 3GISA 1TBQJ 1TQ7A 3E6PL 3HK6A 2PV9A 3EDXA 3LU9A 3HKIA 1JMOL 4RKOA 1JOUA 3B9FL 1TB6L
chains in the Genus database with same CATH superfamily
1A0HA 2B5TA 2ODYA 3BEFA 1TBRJ 3BEIA 4DY7A 1AVGL 2PGQA 2A1DA 1Z8JA 2PUXA 3GISA 1TBQJ 1TQ7A 3E6PL 3HK6A 2PV9A 3EDXA 3LU9A 3HKIA 1JMOL 4RKOA 1JOUA 3B9FL 1TB6L
chains in the Genus database with same CATH topology
1A0HA 2B5TA 2ODYA 3BEFA 1TBRJ 3BEIA 4DY7A 1AVGL 2PGQA 2A1DA 1Z8JA 2PUXA 3GISA 1TBQJ 1TQ7A 3E6PL 3HK6A 2PV9A 3EDXA 3LU9A 3HKIA 1JMOL 4RKOA 1JOUA 3B9FL 1TB6L
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1A0H A;  2B5T A;  2ODY A;  3BEF A;  1TBR J;  3BEI A;  4DY7 A;  1AVG L;  2PGQ A;  2A1D A;  1Z8J A;  2PUX A;  3GIS A;  1TBQ J;  1TQ7 A;  3E6P L;  3HK6 A;  2PV9 A;  3EDX A;  3LU9 A;  3HKI A;  1JMO L;  4RKO A;  1JOU A;  3B9F L;  1TB6 L; 
#chains in the Genus database with same CATH topology
 1A0H A;  2B5T A;  2ODY A;  3BEF A;  1TBR J;  3BEI A;  4DY7 A;  1AVG L;  2PGQ A;  2A1D A;  1Z8J A;  2PUX A;  3GIS A;  1TBQ J;  1TQ7 A;  3E6P L;  3HK6 A;  2PV9 A;  3EDX A;  3LU9 A;  3HKI A;  1JMO L;  4RKO A;  1JOU A;  3B9F L;  1TB6 L; 
#chains in the Genus database with same CATH homology
 1A0H A;  2B5T A;  2ODY A;  3BEF A;  1TBR J;  3BEI A;  4DY7 A;  1AVG L;  2PGQ A;  2A1D A;  1Z8J A;  2PUX A;  3GIS A;  1TBQ J;  1TQ7 A;  3E6P L;  3HK6 A;  2PV9 A;  3EDX A;  3LU9 A;  3HKI A;  1JMO L;  4RKO A;  1JOU A;  3B9F L;  1TB6 L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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