3G6EJ

Co-crystal structure of homoharringtonine bound to the large ribosomal subunit
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
142
structure length
142
Chain Sequence
AEFDADVIVDARDCIMGRVASQVAEQALDGETVAVVNAERAVITGREEQIVEKYEKRVDIGNDNGYFYPKRPDGIFKRTIRGMLPHKKQRGREAFESVRVYLGNPYDEDGEVLDGTSLDRLSNIKFVTLGEISETLGANKTW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S ribosomal RNA
total genus 42
structure length 142
sequence length 142
ec nomenclature
pdb deposition date 2009-02-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
J PF00572 Ribosomal_L13 Ribosomal protein L13
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1180.10 Alpha Beta Alpha-Beta Complex Ribosomal Protein L13p; Chain: A; Ribosomal protein L13 3g6eJ00
3PIPG 4IOAG 1YITJ 1KQSI 1K9MK 1VQKJ 2ZJPG 3CCLJ 1Q86K 1VQ4J 1VQ7J 3J7YK 1J3AA 1W2BI 3CCMJ 1VQ5J 1Q7YK 3CD6J 1M90K 2QEXJ 1QVGI 4IO9G 1VQPJ 3CCQJ 1YIJJ 1S72J 3CCRJ 1KD1K 3CCEJ 1VQMJ 3CPWI 3CMEJ 3PIOG 3OW2I 1KC8K 3I55J 3G4SJ 3CCVJ 3CC2J 3CMAJ 1Q81K 1YJ9J 1K8AK 2OTJJ 2ZJQG 1VQ9J 3CCJJ 3G71J 1VQOJ 1Q82K 1VQ8J 1YJNJ 1JJ2I 1YJWJ 4IOCG 1QVFI 3CCSJ 1VQNJ 3CC4J 1VQLJ 2OTLJ 1N8RK 1M1KK 1VQ6J 3CF5G 3CCUJ 2ZJRG 1YHQJ 1K73K 1YI2J 2QA4J 3I56J 3DLLG 1NJIK 3G6EJ 4V19N 3CXCI 3CC7J
chains in the Genus database with same CATH superfamily
3PIPG 4IOAG 1YITJ 1KQSI 1K9MK 1VQKJ 2ZJPG 3CCLJ 1Q86K 1VQ4J 1VQ7J 3J7YK 1J3AA 1W2BI 3CCMJ 1VQ5J 1Q7YK 3CD6J 1M90K 2QEXJ 1QVGI 4IO9G 1VQPJ 3CCQJ 1YIJJ 1S72J 3CCRJ 1KD1K 3CCEJ 1VQMJ 3CPWI 3CMEJ 3PIOG 3OW2I 1KC8K 3I55J 3G4SJ 3CCVJ 3CC2J 3CMAJ 1Q81K 1YJ9J 1K8AK 2OTJJ 2ZJQG 1VQ9J 3CCJJ 3G71J 1VQOJ 1Q82K 1VQ8J 1YJNJ 1JJ2I 1YJWJ 4IOCG 1QVFI 3CCSJ 1VQNJ 3CC4J 1VQLJ 2OTLJ 1N8RK 1M1KK 1VQ6J 3CF5G 3CCUJ 2ZJRG 1YHQJ 1K73K 1YI2J 2QA4J 3I56J 3DLLG 1NJIK 3G6EJ 4V19N 3CXCI 3CC7J
chains in the Genus database with same CATH topology
3PIPG 4IOAG 1YITJ 1KQSI 1K9MK 1VQKJ 2ZJPG 3CCLJ 1Q86K 1VQ4J 1VQ7J 3J7YK 1J3AA 1W2BI 3CCMJ 1VQ5J 1Q7YK 3CD6J 1M90K 2QEXJ 1QVGI 4IO9G 1VQPJ 3CCQJ 1YIJJ 1S72J 3CCRJ 1KD1K 3CCEJ 1VQMJ 3CPWI 3CMEJ 3PIOG 3OW2I 1KC8K 3I55J 3G4SJ 3CCVJ 3CC2J 3CMAJ 1Q81K 1YJ9J 1K8AK 2OTJJ 2ZJQG 1VQ9J 3CCJJ 3G71J 1VQOJ 1Q82K 1VQ8J 1YJNJ 1JJ2I 1YJWJ 4IOCG 1QVFI 3CCSJ 1VQNJ 3CC4J 1VQLJ 2OTLJ 1N8RK 1M1KK 1VQ6J 3CF5G 3CCUJ 2ZJRG 1YHQJ 1K73K 1YI2J 2QA4J 3I56J 3DLLG 1NJIK 3G6EJ 4V19N 3CXCI 3CC7J
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PIP G;  4IOA G;  1YIT J;  1KQS I;  1K9M K;  1VQK J;  2ZJP G;  3CCL J;  1Q86 K;  1VQ4 J;  1VQ7 J;  3J7Y K;  1J3A A;  1W2B I;  3CCM J;  1VQ5 J;  1Q7Y K;  3CD6 J;  1M90 K;  2QEX J;  1QVG I;  4IO9 G;  1VQP J;  3CCQ J;  1YIJ J;  1S72 J;  3CCR J;  1KD1 K;  3CCE J;  1VQM J;  3CPW I;  3CME J;  3PIO G;  3OW2 I;  1KC8 K;  3I55 J;  3G4S J;  3CCV J;  3CC2 J;  3CMA J;  1Q81 K;  1YJ9 J;  1K8A K;  2OTJ J;  2ZJQ G;  1VQ9 J;  3CCJ J;  3G71 J;  1VQO J;  1Q82 K;  1VQ8 J;  1YJN J;  1JJ2 I;  1YJW J;  4IOC G;  1QVF I;  3CCS J;  1VQN J;  3CC4 J;  1VQL J;  2OTL J;  1N8R K;  1M1K K;  1VQ6 J;  3CF5 G;  3CCU J;  2ZJR G;  1YHQ J;  1K73 K;  1YI2 J;  2QA4 J;  3I56 J;  3DLL G;  1NJI K;  3G6E J;  4V19 N;  3CXC I;  3CC7 J; 
#chains in the Genus database with same CATH topology
 3PIP G;  4IOA G;  1YIT J;  1KQS I;  1K9M K;  1VQK J;  2ZJP G;  3CCL J;  1Q86 K;  1VQ4 J;  1VQ7 J;  3J7Y K;  1J3A A;  1W2B I;  3CCM J;  1VQ5 J;  1Q7Y K;  3CD6 J;  1M90 K;  2QEX J;  1QVG I;  4IO9 G;  1VQP J;  3CCQ J;  1YIJ J;  1S72 J;  3CCR J;  1KD1 K;  3CCE J;  1VQM J;  3CPW I;  3CME J;  3PIO G;  3OW2 I;  1KC8 K;  3I55 J;  3G4S J;  3CCV J;  3CC2 J;  3CMA J;  1Q81 K;  1YJ9 J;  1K8A K;  2OTJ J;  2ZJQ G;  1VQ9 J;  3CCJ J;  3G71 J;  1VQO J;  1Q82 K;  1VQ8 J;  1YJN J;  1JJ2 I;  1YJW J;  4IOC G;  1QVF I;  3CCS J;  1VQN J;  3CC4 J;  1VQL J;  2OTL J;  1N8R K;  1M1K K;  1VQ6 J;  3CF5 G;  3CCU J;  2ZJR G;  1YHQ J;  1K73 K;  1YI2 J;  2QA4 J;  3I56 J;  3DLL G;  1NJI K;  3G6E J;  4V19 N;  3CXC I;  3CC7 J; 
#chains in the Genus database with same CATH homology
 3PIP G;  4IOA G;  1YIT J;  1KQS I;  1K9M K;  1VQK J;  2ZJP G;  3CCL J;  1Q86 K;  1VQ4 J;  1VQ7 J;  3J7Y K;  1J3A A;  1W2B I;  3CCM J;  1VQ5 J;  1Q7Y K;  3CD6 J;  1M90 K;  2QEX J;  1QVG I;  4IO9 G;  1VQP J;  3CCQ J;  1YIJ J;  1S72 J;  3CCR J;  1KD1 K;  3CCE J;  1VQM J;  3CPW I;  3CME J;  3PIO G;  3OW2 I;  1KC8 K;  3I55 J;  3G4S J;  3CCV J;  3CC2 J;  3CMA J;  1Q81 K;  1YJ9 J;  1K8A K;  2OTJ J;  2ZJQ G;  1VQ9 J;  3CCJ J;  3G71 J;  1VQO J;  1Q82 K;  1VQ8 J;  1YJN J;  1JJ2 I;  1YJW J;  4IOC G;  1QVF I;  3CCS J;  1VQN J;  3CC4 J;  1VQL J;  2OTL J;  1N8R K;  1M1K K;  1VQ6 J;  3CF5 G;  3CCU J;  2ZJR G;  1YHQ J;  1K73 K;  1YI2 J;  2QA4 J;  3I56 J;  3DLL G;  1NJI K;  3G6E J;  4V19 N;  3CXC I;  3CC7 J; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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