3CCLJ

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation u2535c. density for anisomycin is visible but not included in model.
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
142
structure length
142
Chain Sequence
AEFDADVIVDARDCIMGRVASQVAEQALDGETVAVVNAERAVITGREEQIVEKYEKRVDIGNDNGYFYPKRPDGIFKRTIRGMLPHKKQRGREAFESVRVYLGNPYDEDGEVLDGTSLDRLSNIKFVTLGEISETLGANKTW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 40
structure length 142
sequence length 142
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
J PF00572 Ribosomal_L13 Ribosomal protein L13
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1180.10 Alpha Beta Alpha-Beta Complex Ribosomal Protein L13p; Chain: A; Ribosomal protein L13 3cclJ00
3PIPG 3CPWI 1S72J 1VQPJ 1K8AK 3PIOG 1NJIK 3J7YK 1KD1K 2QEXJ 1YJ9J 3CC2J 1Q82K 3CD6J 3CXCI 1YITJ 1YHQJ 1VQ4J 3I55J 1VQ6J 1KQSI 3CCJJ 1YI2J 3CCRJ 1VQ5J 3G4SJ 2ZJPG 1VQLJ 1YIJJ 1N8RK 3G71J 1M90K 1VQMJ 3CCMJ 1YJNJ 1K73K 1VQOJ 4IOCG 1W2BI 1VQNJ 3CCUJ 3I56J 1VQ7J 1QVFI 3G6EJ 3CC7J 1QVGI 3OW2I 1VQKJ 2QA4J 1Q86K 2ZJQG 2ZJRG 3CF5G 1YJWJ 3CMAJ 3CCVJ 1VQ9J 4IOAG 3CMEJ 3CCQJ 1VQ8J 3CCLJ 1J3AA 3CCEJ 1JJ2I 3CCSJ 3DLLG 4IO9G 1K9MK 2OTLJ 2OTJJ 4V19N 1M1KK 1KC8K 1Q81K 3CC4J 1Q7YK
chains in the Genus database with same CATH superfamily
3PIPG 3CPWI 1S72J 1VQPJ 1K8AK 3PIOG 1NJIK 3J7YK 1KD1K 2QEXJ 1YJ9J 3CC2J 1Q82K 3CD6J 3CXCI 1YITJ 1YHQJ 1VQ4J 3I55J 1VQ6J 1KQSI 3CCJJ 1YI2J 3CCRJ 1VQ5J 3G4SJ 2ZJPG 1VQLJ 1YIJJ 1N8RK 3G71J 1M90K 1VQMJ 3CCMJ 1YJNJ 1K73K 1VQOJ 4IOCG 1W2BI 1VQNJ 3CCUJ 3I56J 1VQ7J 1QVFI 3G6EJ 3CC7J 1QVGI 3OW2I 1VQKJ 2QA4J 1Q86K 2ZJQG 2ZJRG 3CF5G 1YJWJ 3CMAJ 3CCVJ 1VQ9J 4IOAG 3CMEJ 3CCQJ 1VQ8J 3CCLJ 1J3AA 3CCEJ 1JJ2I 3CCSJ 3DLLG 4IO9G 1K9MK 2OTLJ 2OTJJ 4V19N 1M1KK 1KC8K 1Q81K 3CC4J 1Q7YK
chains in the Genus database with same CATH topology
3PIPG 3CPWI 1S72J 1VQPJ 1K8AK 3PIOG 1NJIK 3J7YK 1KD1K 2QEXJ 1YJ9J 3CC2J 1Q82K 3CD6J 3CXCI 1YITJ 1YHQJ 1VQ4J 3I55J 1VQ6J 1KQSI 3CCJJ 1YI2J 3CCRJ 1VQ5J 3G4SJ 2ZJPG 1VQLJ 1YIJJ 1N8RK 3G71J 1M90K 1VQMJ 3CCMJ 1YJNJ 1K73K 1VQOJ 4IOCG 1W2BI 1VQNJ 3CCUJ 3I56J 1VQ7J 1QVFI 3G6EJ 3CC7J 1QVGI 3OW2I 1VQKJ 2QA4J 1Q86K 2ZJQG 2ZJRG 3CF5G 1YJWJ 3CMAJ 3CCVJ 1VQ9J 4IOAG 3CMEJ 3CCQJ 1VQ8J 3CCLJ 1J3AA 3CCEJ 1JJ2I 3CCSJ 3DLLG 4IO9G 1K9MK 2OTLJ 2OTJJ 4V19N 1M1KK 1KC8K 1Q81K 3CC4J 1Q7YK
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PIP G;  3CPW I;  1S72 J;  1VQP J;  1K8A K;  3PIO G;  1NJI K;  3J7Y K;  1KD1 K;  2QEX J;  1YJ9 J;  3CC2 J;  1Q82 K;  3CD6 J;  3CXC I;  1YIT J;  1YHQ J;  1VQ4 J;  3I55 J;  1VQ6 J;  1KQS I;  3CCJ J;  1YI2 J;  3CCR J;  1VQ5 J;  3G4S J;  2ZJP G;  1VQL J;  1YIJ J;  1N8R K;  3G71 J;  1M90 K;  1VQM J;  3CCM J;  1YJN J;  1K73 K;  1VQO J;  4IOC G;  1W2B I;  1VQN J;  3CCU J;  3I56 J;  1VQ7 J;  1QVF I;  3G6E J;  3CC7 J;  1QVG I;  3OW2 I;  1VQK J;  2QA4 J;  1Q86 K;  2ZJQ G;  2ZJR G;  3CF5 G;  1YJW J;  3CMA J;  3CCV J;  1VQ9 J;  4IOA G;  3CME J;  3CCQ J;  1VQ8 J;  3CCL J;  1J3A A;  3CCE J;  1JJ2 I;  3CCS J;  3DLL G;  4IO9 G;  1K9M K;  2OTL J;  2OTJ J;  4V19 N;  1M1K K;  1KC8 K;  1Q81 K;  3CC4 J;  1Q7Y K; 
#chains in the Genus database with same CATH topology
 3PIP G;  3CPW I;  1S72 J;  1VQP J;  1K8A K;  3PIO G;  1NJI K;  3J7Y K;  1KD1 K;  2QEX J;  1YJ9 J;  3CC2 J;  1Q82 K;  3CD6 J;  3CXC I;  1YIT J;  1YHQ J;  1VQ4 J;  3I55 J;  1VQ6 J;  1KQS I;  3CCJ J;  1YI2 J;  3CCR J;  1VQ5 J;  3G4S J;  2ZJP G;  1VQL J;  1YIJ J;  1N8R K;  3G71 J;  1M90 K;  1VQM J;  3CCM J;  1YJN J;  1K73 K;  1VQO J;  4IOC G;  1W2B I;  1VQN J;  3CCU J;  3I56 J;  1VQ7 J;  1QVF I;  3G6E J;  3CC7 J;  1QVG I;  3OW2 I;  1VQK J;  2QA4 J;  1Q86 K;  2ZJQ G;  2ZJR G;  3CF5 G;  1YJW J;  3CMA J;  3CCV J;  1VQ9 J;  4IOA G;  3CME J;  3CCQ J;  1VQ8 J;  3CCL J;  1J3A A;  3CCE J;  1JJ2 I;  3CCS J;  3DLL G;  4IO9 G;  1K9M K;  2OTL J;  2OTJ J;  4V19 N;  1M1K K;  1KC8 K;  1Q81 K;  3CC4 J;  1Q7Y K; 
#chains in the Genus database with same CATH homology
 3PIP G;  3CPW I;  1S72 J;  1VQP J;  1K8A K;  3PIO G;  1NJI K;  3J7Y K;  1KD1 K;  2QEX J;  1YJ9 J;  3CC2 J;  1Q82 K;  3CD6 J;  3CXC I;  1YIT J;  1YHQ J;  1VQ4 J;  3I55 J;  1VQ6 J;  1KQS I;  3CCJ J;  1YI2 J;  3CCR J;  1VQ5 J;  3G4S J;  2ZJP G;  1VQL J;  1YIJ J;  1N8R K;  3G71 J;  1M90 K;  1VQM J;  3CCM J;  1YJN J;  1K73 K;  1VQO J;  4IOC G;  1W2B I;  1VQN J;  3CCU J;  3I56 J;  1VQ7 J;  1QVF I;  3G6E J;  3CC7 J;  1QVG I;  3OW2 I;  1VQK J;  2QA4 J;  1Q86 K;  2ZJQ G;  2ZJR G;  3CF5 G;  1YJW J;  3CMA J;  3CCV J;  1VQ9 J;  4IOA G;  3CME J;  3CCQ J;  1VQ8 J;  3CCL J;  1J3A A;  3CCE J;  1JJ2 I;  3CCS J;  3DLL G;  4IO9 G;  1K9M K;  2OTL J;  2OTJ J;  4V19 N;  1M1K K;  1KC8 K;  1Q81 K;  3CC4 J;  1Q7Y K; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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